Virco establishes comprehensive set of clinical cutoffs for the vircoTYPE HIV-1 resistance test

Washington, D.C., October 31, 2004 Investigators from Virco today presented data that establishes a comprehensive set of clinical cutoffs -- a newly established threshold for optimal selection and evaluation of antiretroviral regimens -- for the virco®TYPE HIV-1 resistance test. These reference values are derived from the largest clinical outcomes database used to generate clinical cutoffs, and apply a consistent and clinically relevant approach to help physicians better evaluate HIV drug resistance information. These clinical cutoffs are available for a wider range of antiretroviral drugs than those offered by other HIV resistance tests.

In her presentation today at the 44th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Lee Bacheler, PhD, vice president, Clinical Virology, at Virco, demonstrated how clinical cutoffs for the virco®TYPE HIV-1 assay, based on a large and high-quality outcomes database that incorporates more than 3,000 therapeutic regimens, provide physicians with clinically relevant resistance information. She and her colleagues employed virco®TYPE analysis of viral genotypes to predict quantitative phenotypic resistance levels. Mathematical models of virologic response to antiretroviral drugs at eight and 24 weeks versus baseline fold change in IC50 (concentrations of drugs that inhibit 50% of viral replication) were constructed using linear regression. Clinical cutoffs (CCOs) were defined as virco®TYPE-predicted fold change values for 20% and 80% loss of viral load response.

"Our study supports the value of clinical cutoffs in facilitating rational selection of antiretroviral treatment," commented Dr. Bacheler. "The clinical cutoffs enhance the value of the virco®TYPE HIV-1 test by applying consistent definitions across antiretroviral drugs. The results are more closely related to actual treatment practices, with the potential to improve medical management of people with HIV." <

Contact: Catherine Collins
Sensei Health

Page: 1 2 3

Related medicine news :

1. Virco first to introduce drug-specific biological cut-offs for its HIV resistance tests
2. NIA establishes new demography centers to enhance knowledge about older americans
3. U of MN establishes nations first endowed chair in sexual health
4. Mayo Clinic establishes landmark research program to predict and prevent alcoholism
5. UCL study establishes common biological ground for maternal and romantic love in humans
6. Gene therapy establishes a TRAIL to arthritis treatment
7. New program establishes distinguished scholar in thrombosis
8. U of Washington establishes $9 million center to study hepatitis-induced liver disease
9. Cancer revealed: New $10M grant establishes cancer imaging center
10. Wake Forest establishes Maya Angelou Research Center on minority health
11. Fogarty International Center establishes Sheldon M. Wolff, MD Fellowship On International Health

Post Your Comments:

(Date:2/13/2019)... ... February 13, 2019 , ... Today, leaders ... four days of programming occurring at SXSW 2019 in Austin, TX. Organizers ... and philanthropy to innovate, collaborate and activate initiatives aimed at increasing health ...
(Date:2/13/2019)... ... February 13, 2019 , ... That wintry landscape outside the window appears, oh, ... and driveways. Then, the snow can quickly become a pain in the “back, shoulder, ... remove it,” says noted orthopaedic surgeon Kevin D. Plancher, MD, MPH , who ...
(Date:2/13/2019)... , ... February 13, 2019 , ... Dr. Jig ... welcome Dr. Muizz Merchant, an exceptionally talented and knowledgeable dentist from St. ... of modern dental techniques, such as CEREC same-day dentistry, root canals and emergency treatment. ...
(Date:2/13/2019)... ... 13, 2019 , ... Asana Recovery is accepting applications from college-bound or current ... a medical-related course of study in California, the $1,000 scholarship will be awarded to ... health treatment, and how it has led them to their chosen field of study. ...
(Date:2/12/2019)... Neb. (PRWEB) , ... February ... ... healthcare market research and consulting organization, devoted to helping hospital leaders, staff, ... website at http://www.prccustomresearch.com . The website now features a streamlined design, ...
Breaking Medicine News(10 mins):
(Date:2/13/2019)... PARK, Texas (PRWEB) , ... February 13, 2019 ... ... new CD8801 and CD8826 Thin Clients at HIMSS 2019 US in Orlando, Florida. ... manufacturing industries at low prices of $199 and $520 and above respectively. ...
(Date:2/13/2019)... ... February 13, 2019 , ... Gastro Health, LLC (“Gastro ... Gastroenterology Center, P.A. DBA Gastroenterology Specialists (“Gastroenterology Specialists”), a leading physician group with ... acquisition in the Central Florida market, after it acquired Central Florida Gastroenterology in ...
(Date:2/13/2019)... Utah (PRWEB) , ... February 13, 2019 , ... Published ... Music to Reduce Auditory Hypersensitivity in Children appears in Vol 11, No 1 ... and Alex Doman founder of Advanced Brain Technologies .     , ...
Breaking Medicine Technology:
Cached News: