HOME >> MEDICINE >> NEWS
Virus in babies may cause asthma later on

St. Louis, July 15, 2002 While most scientists believe that allergies cause asthma, researchers at Washington University School of Medicine in St. Louis are uncovering a second potential cause for this common respiratory illness. Their new model suggests that a viral infection in the first years of life may leave a lasting mark on the immune system, causing chronic respiratory problems later on.

"While the allergic response may increase during an asthma attack, our research suggests that the anti-viral response also increases," says Michael J. Holtzman, M.D., the Selma and Herman Seldin Professor of Medicine and professor of cell biology and physiology. "We think that a virus in infancy or childhood creates a hit-and-run effect, where a brief infection causes permanent changes in the body's anti-viral system."

Holtzman led the study, which appears in the July 15 issue of the Journal of Clinical Investigation.

The most common cause of lower respiratory illness in children is paramyxoviral infection, which often results in chronic wheezing regardless of whether the child develops allergies. But researchers have yet to figure out how the short-term influence of this viral infection leads to a long-term condition of respiratory inflammation and distress.

Holtzman's team examined mice with bronchiolitis inflamed airways caused by paramyxoviral infection. The mouse disease mimics paramyxoviral infection in humans. These mice responded immediately to the infection immune cells flooded the lining of the respiratory tract, attacking infectious cells and inflaming the tissues. Weeks after infection, the airways of the lung remained extremely sensitive, or hyperreactive, and the airway lining became populated with mucus-producing cells. Each of these changes airway hyperreactivity and cellular remodeling lasted for at least one year and perhaps indefinitely. "Since each of these changes also is a long-term symptom of asthma, these
'"/>

Contact: Gila Reckess
reckessg@msnotes.wustl.edu
314-286-0109
Washington University School of Medicine
10-Jul-2002


Page: 1 2

Related medicine news :

1. Virus that can infect both mice and humans is driven to extinction with cancer drug
2. Study Shows Three-Drug "Cocktail" Needed To Keep AIDS Virus Curbed
3. AIDS Treatments Seek To Eradicate Virus, Restore Immunity
4. Sunflower seed oil can protect low birth weight babies from infection
5. Three out of the four million newborn babies who die each year could be saved
6. Daily supplement may boost birthweight of babies in the developing world
7. Mothers exposure to air pollutants linked to chromosome damage in babies
8. Cooling lessens brain damage in sick newborn babies
9. New system may help babies avoid brain damage
10. Outlook is bleak for the smallest premature babies: 80 percent have impairment
11. Twenty-Year prospective study of pregnant women with inflammatory bowel disease finds healthy babies

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/5/2020)... Fla. (PRWEB) , ... August 05, 2020 , ... AdventHealth ... strategy for safely reopening for class on Monday, August 12, 2020. AdventHealth provided the ... the spread of COVID-19 in the classroom setting. , “We are taking extra ...
(Date:8/5/2020)... ... August 05, 2020 , ... ChronWell, a ... Director of Clinical Services and Myron Falchuk, M.D. as an Advisor, to further ... has achieved incredible growth as demand for remote care management services soared amidst ...
(Date:8/5/2020)... ... , ... Today, YPO Africa , a global leadership community of chief ... announced that they have entered into a unique bilateral alliance. The key aim of ... in their African impact efforts, with an initial focus on YPO’s Lead COVID-19 ...
(Date:8/5/2020)... ... , ... Today, Power to Decide’s One Key Question was recognized ... Station Best Practice Award. The One Key Question program is a transformative tool that ... have a child. One Key Question is used by thousands of health care, social ...
(Date:8/3/2020)... ... 03, 2020 , ... The process uses needlepoint bipolar ionization ... Arena, the Phoenix airport, the Mayo Clinic, Ramstein Air Force Base, Harvard University, ... Solutions (GPS), the manufacturers of the system, most viruses and other particles in ...
Breaking Medicine News(10 mins):
(Date:7/22/2020)... Ore. (PRWEB) , ... July 22, 2020 , ... ... safely re-open schools is a critical topic receiving national attention. A new 8 ... critical issue for creating and maintaining safe schools. , The Germ-Fogger™ disinfecting-fogger is ...
(Date:7/18/2020)... ... 17, 2020 , ... The Women’s Fund Miami-Dade has launched ... who are experiencing abuse know that services are available 24/7, and to encourage ... County’s Coordinated Victim’s Assistance Center (CVAC) helpline. Although there hasn’t been an overwhelming ...
(Date:7/10/2020)... ... 10, 2020 , ... Precision ADM, Inc. (“Precision ADM” or ... announced that their CANSWAB™ nasopharyngeal swabs are the first Canadian-made COVID-19 testing product ... swab design and has trademarked the name CANSWAB™ for distribution. The collection capability ...
Breaking Medicine Technology:
Cached News: