HOME >> MEDICINE >> NEWS
Vitamin E may not prevent cancer or cardiovascular events, but may increase risk for heart failure

Patients who took vitamin E supplements for about 7 years did not have their risk of cancer or cardiovascular events significantly reduced, and in fact some had an increased risk of heart failure, according to a study in the March 16 issue of JAMA.

Experimental and epidemiological data have suggested that vitamin E supplementation may prevent cancer and cardiovascular events, according to background information in the article. Clinical trials have generally failed to confirm benefits, possibly due to their relatively short duration.

Eva Lonn, M.D., of the Population Health Research Institute and McMaster University, Hamilton Health Sciences Corporation, Hamilton, Ontario, Canada, and colleagues conducted a study to evaluate whether long-term supplementation with vitamin E decreases the risk of cancer, cancer death, and major cardiovascular events. The randomized, double-blind, placebo-controlled trial (Heart Outcomes Prevention Evaluation [HOPE]) was initially conducted between December 21, 1993, and April 15, 1999, and included patients at least 55 years old with vascular disease or diabetes mellitus. This trial was extended (HOPEThe Ongoing Outcomes [HOPE-TOO]) to between April 16, 1999, and May 26, 2003.

Of the initial 267 HOPE centers that had enrolled 9,541 patients, 174 centers participated in the HOPE-TOO trial. Of 7,030 patients enrolled at these centers, 916 were deceased at the beginning of the extension, 1,382 refused participation, 3,994 continued to take the study intervention, and 738 agreed to follow-up. Median duration of follow-up was 7.0 years. Patients received a daily dose of natural source vitamin E (400 IU) or matching placebo.

The researchers found: "In the HOPE and HOPE-TOO trials, the daily administration of 400 IU of natural source vitamin E for a median of 7.0 years had no clear impact on fatal and nonfatal cancers, major cardiovascular events, or deaths. We observed an increase in the risk of heart failu
'"/>

Contact: Veronica McGuire
905-525-9140
JAMA and Archives Journals
15-Mar-2005


Page: 1 2

Related medicine news :

1. Vitamin C reduces level of C-reactive protein, finds UC Berkeley-led study
2. Vitamins good for some older women/bad for others
3. Vitamin B-12 levels linked to bone loss in aging women
4. Vitamin supplement use may reduce effects of Alzheimers disease
5. Vitamins help treat depression
6. Vitamin D deficiency emerges as new epidemic
7. Vitamins C and E improve cardiovascular health in children with high cholesterol, study says
8. Vitamins C and E may enhance effectiveness of insulin for diabetes
9. Vitamins valuable for baby boomers eye disease
10. Vitamin E fails to join heart-health regimen
11. Vitamins C and E support breathing following an operation

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/15/2019)... ... , ... Heritage Woods of Rockford Administrator Jaclyn O’Keefe has been named Administrator ... is part of the NCAL Awards Program, which recognizes exemplary assisted living caregivers. Honorees ... year’s recipients is that they all go out of their way to ensure assisted ...
(Date:8/14/2019)... ... , ... New Hampshire-based Vera Roasting Company , makers of the only ... line of CBD-infused coffees with the release of a new higher-dosage organic Wellness ... “We are excited to expand our CBD-infused product lines to include a more potent ...
(Date:8/14/2019)... ... ... Today, consumers are taking a harder look at what goes into their bodies. ... levels. The trick is finding food and beverages that are delicious and nutritious to ... created Chase – a delicious, guilt free cocktail mixer that doesn’t compromise ...
(Date:8/12/2019)... ... August 12, 2019 , ... Injured ... to donations received through the 4th annual Lockton Warfighter Sports Charity Challenge being ... , Participating in the event again this year will be fifty ...
(Date:8/9/2019)... ... August 09, 2019 , ... ... its second opioid treatment program (OTP) in Ohio. MedMark Lebanon will provide medically-supervised ... The clinic, located at 1521 Walmart Drive, is now accepting patients. , ...
Breaking Medicine News(10 mins):
(Date:8/15/2019)... , ... August 15, 2019 , ... Men’s Health Memorial ... with health care experts and learn how to regain their strength and vitality. ... taking the first step to do something about it is not always easy,” said ...
(Date:8/15/2019)... ... 2019 , ... Inc. magazine revealed that Skysis is No. ... nation’s fastest-growing private companies. The list represents a unique look at the most ... Dell, Domino’s Pizza, Pandora, Timberland, LinkedIn, Yelp, Zillow, and many other well-known names ...
(Date:8/14/2019)... ANDOVER, Mass. (PRWEB) , ... August 14, 2019 ... ... Andover, Massachusetts, is continuing its research and development of its drug platform GVT ... Illness (GWI), ALS, and Parkinson’s disease among others. Overwhelming data from multiple animal ...
Breaking Medicine Technology:
Cached News: