Wayne State and Virginia chemist wins national award for work with drugs

Carl R. Johnson of Hartfield, Va., will be honored August 20 by the world's largest scientific society for helping develop more efficient ways to invent and produce pharmaceutical drugs. He will receive the 2002 Arthur C. Cope Senior Scholar Award from the American Chemical Society at its national meeting in Boston.

During his 40-year career at Wayne State University in Detroit, Johnson's work took a number of twists but maintained a common theme. "Throughout my career," he said, "I've tried to relate chemistry to biology, to do things of interest to the pharmaceutical industry."

He began with studying sulfur-based compounds and how he could use them to tailor-make starting materials and methods to build biologically active compounds. That was more than 200 research papers, seven books and some 200 doctorate and post-doctorate students ago.

In the last decade, said Johnson, researchers have learned that sugar molecules -- in addition to providing energy for humans and other organisms, as does glucose, and structural support, as does cellulose -- serve as "ID tags" on the surface of cells. Hormones use them to identify their target tissue, for example. But so do infectious organisms, like viruses.

"So we began to look at groups of molecules that would mimic the sugars in hopes they might complex with the parasite, virus or bacterium -- and by 'complexing' with it would prevent it from attacking the host cell," said Johnson. "And we tried to make those molecules using unusual chemistry." For instance, he and his group would assemble a complex sugar unit using bacterial enzymes and simple organic starting materials, he added.

Growing up in the small town of Orange, Va., "the closest thing we had to a scientist was our local pharmacist. That's largely why I went to pharmacy school," said Johnson. "But I soon found the thing that was very interesting to me was a chemistry course I took. I knew then what I really wanted to do was be

Contact: Allison Byrum
American Chemical Society

Page: 1 2

Related medicine news :

1. Wayne State chemist wins national award for new ways to make natures molecules
2. International breast cancer prevention study launches in the United States and Canada
3. Statement on the findings of the Womens Health Study
4. States find alternate routes to health coverage
5. State policies decrease youth smoking, drinking and sex
6. State of the heart news conference
7. CDC: Update on current influenza season and vaccine supply in the United States
8. Immigrants, beware: Living in the United States is fattening
9. NIH panel issues State-of-the-Science statement on end-of-life care
10. Landmark survey reveals asthma in children remains significantly out of control in the United States
11. NIH convenes State-of-the-Sceince Conference on Improving End-of-Life Care

Post Your Comments:

(Date:10/13/2017)... ... October 13, 2017 , ... ProVest Insurance Group, ... Dallas, Miami, and Raleigh regions, is organizing an extended charity drive to benefit ... deadly chromosome abnormality. , After struggling since birth with several health challenges, T.J. ...
(Date:10/13/2017)... , ... October 13, 2017 , ... ... the certification process to promote standards of excellence for the field of eating ... for March 22 – 25, 2018 in Orlando, Florida at the Omni Resort ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Many families have ... many long-term care insurance companies have a waiver for care if the client has ... period, when the family pays for care, is often waived, so the benefits from ...
(Date:10/13/2017)... ... October 13, 2017 , ... Talented host, actor Rob ... sciatica in a new episode of "Success Files," which is an award-winning educational ... and investigates each subject in-depth with passion and integrity. , Sciatica occurs when ...
(Date:10/12/2017)... ... October 12, 2017 , ... CitiDent and San ... using cutting-edge Oventus O2Vent technology. As many as 18 million Americans are ... cessation in breathing. Oral appliances can offer significant relief to about 75 percent ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... , Oct. 6, 2017   Provista, ... more than $100 billion in purchasing power, today announced ... and information. The Newsroom is the online ... industry trends, infographics, expert bios, news releases, slideshows and ... access to a wealth of resources at their fingertips, ...
(Date:10/2/2017)... , Oct. 2, 2017 Diplomat Pharmacy, Inc. ... Day Software and Consulting, LLC , and named its ... Software, based in Tennessee , will ... Day expands EnvoyHealth,s service offerings for health care partners ... "In an interoperable world, ...
(Date:9/28/2017)... , Sept. 28, 2017 Hill-Rom Holdings, ... 2017 earnings conference call and webcast on Friday, November ... a.m. (EDT) and ending at approximately 8:30 a.m. (CDT) ... discussing the company,s 2017 financial performance and guidance for ... opportunities, initiatives to enhance operational performance, and long-range financial ...
Breaking Medicine Technology:
Cached News: