HOME >> MEDICINE >> NEWS
Widely used anti-bacterial inhibits parasites that cause malaria and toxoplasmosis

Triclosan, a common antiseptic used in household products such as toothpaste, skin creams, and deodorants, kills the parasites responsible for malaria and toxoplasmosis, even at very low concentrations, reports a team of researchers from the United States and the United Kingdom in the February issue of the International Journal for Parasitology.

Triclosan has been used as an antiseptic since the 1960s. It blocks an enzyme, known as "FabI," that bacteria need to manufacture the fatty acids used in cell membranes. Because animals possess a very different set of enzymes, triclosan does not interfere with this process in humans. This has led to its widespread use in over-the-counter preparations used on the skin or in the mouth.

This common, inexpensive antimicrobial is remarkably effective against these parasites at concentrations that have no detectable toxicity, said first author Rima McLeod, M.D., the Jules and Doris Stein Research to Prevent Blindness Professor of Ophthalmology and Visual Sciences at the University of Chicago.

"That's good news because we urgently need new and better medicines to treat malaria and toxoplasmosis," she added. "The parasites that cause malaria are resistant to many of the available drugs, and there is no medication that affects the latent life-cycle stages of the parasite that causes toxoplasmosis."

"This finding gives us a blueprint to design an effective and safe new drug," said Craig Roberts of the University of Strathclyde, UK.

Malaria affects more than 300 million people worldwide and kills an estimated 3,000 people, mostly children, each day. Although most cases originate in the tropics, there has been a steady increase in U.S. and European repo
'"/>

Contact: John Easton
jeaston@uchospitals.edu
773-702-6241
University of Chicago Medical Center
5-Feb-2001


Page: 1 2 3

Related medicine news :

1. Widely used breast cancer drug not linked to stroke
2. Widely used treatment for head injuries found to be harmful
3. Widely used anti-nausea drug may interfere with cancer chemotherapy
4. Newest Depression Medications Widely Prescribed For Children
5. Widely Used Therapy May Not Be Effective In Treatment Of Acute Stroke
6. Personality, Thought To Be Stable Over Time, Changes In Healthy People Who Take A Widely Used Anti-Depressant
7. Stat5 protein inhibits spread of breast cancer cells
8. Scripps Research Institute group designs DNA vaccine that inhibits growth of cancerous tumors
9. Signal identified that enables malarial parasites to target blood cells
10. A little blue and purple helps body fend off deadly parasites
11. Exercise-induced shortness of breath not always caused by asthma

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/16/2019)... ... June 14, 2019 , ... ... Security solutions, today announced it has received the coveted “2019 Best DLP Solution ... that Works Platform along with the latest additions to its Data Security Portfolio ...
(Date:6/14/2019)... , ... June 14, 2019 , ... ... Tempur-Pedic® Mattress & Pink Bag Event® scheduled for Saturday, July 13th. UBCF is ... men and children directly impacted by breast cancer. This second event was added ...
(Date:6/13/2019)... ... June 13, 2019 , ... MMJ BioPharma Cultivation, a premier ... memorandum of understanding (MOU) with MMJ International Holdings to grow cannabis and supply ... BioPharma Cultivation will be supplying MMJIH with extracts from the marijuana plant to ...
(Date:6/13/2019)... ... June 13, 2019 , ... Pure Ratios, the ... cannabis delivery company, Driven Deliveries, Inc., the only publicly traded cannabis delivery service ... the population of California with overnight cannabis delivery to major thriving markets such ...
(Date:6/13/2019)... ... June 13, 2019 , ... ... everyone in healthcare, today announced that Jon Elwell, the company’s CEO, has been ... DirectTrust is a non-profit health care industry alliance created to support ...
Breaking Medicine News(10 mins):
(Date:6/13/2019)... ... June 13, 2019 , ... Homecare Homebase ... the new Smart Scheduling product, part of the HCHB Intelligence Suite, at the ... uses complex algorithms to create highly efficient routing, mapping and scheduling for home ...
(Date:6/13/2019)... ... 13, 2019 , ... Access Healthcare , a leading provider of healthcare ... at the HFMA Annual Conference 2019 which will be held on June ... Access Healthcare, says, “HFMA Annual Conference has inspired us in many ways – right ...
(Date:6/13/2019)... ... , ... RxNT announced today that it has been named by ... RxNT is a leader in healthcare technology solutions. This is the fourth time RxNT ... highlight the best software products from North American small businesses. RxNT won the FrontRunner ...
Breaking Medicine Technology:
Cached News: