Wilmington chemist wins national award for drug development

Chemist Paul S. Anderson of Lansdale, Pa., will be honored April 3 by the world's largest scientific society for directing the development of such drugs as Zocor for high cholesterol, Trusopt for glaucoma, and Crixivan and Sustiva for HIV. He will receive the 2001 Award in Industrial Chemistry from the American Chemical Society at its 221st national meeting in San Diego.

In a career that has involved shepherding Merck and DuPont pharmaceuticals from laboratory to market, Anderson concludes it's "a strong sense of community values" that makes the difference in drug discovery.

"That's what makes teams of researchers thrive," explained Anderson, the senior vice president of chemical and physical sciences at DuPont Pharmaceuticals Co. "You know somewhere in that sea of possibilities there is an answer. It comes when different people make little discoveries, share information, and work together to add it all up."

The discoveries of Crixivan and Sustiva, drugs that attack human immunodeficiency virus, each required the teamwork of over 100 experts, Anderson said from his Wilmington, Del., office.

"Both discovery processes were incredibly frustrating. Some molecules we made weren't soluble enough, others not potent enough, broke down too rapidly or couldn't get blood levels high enough to really attack HIV," he said.

Each project team tried and discarded about 1,000 drug candidates before Crixivan, a protease inhibitor, and Sustiva, a reverse transcriptase inhibitor, made it to market in 1996 and 1998, respectively.

Himself a medicinal chemist, Anderson said the project groups he directs are now developing the second generation of AIDS-fighting drugs. One is in Phase I and another in Phase II clinical trials.

Anderson said it was his father, a school superintendent, who sparked his career interest: "I remember we used to do kitchen-sink experiments at home while I was still in grade school," he said. "It got me really comfort

Contact: Rodney Pearson
American Chemical Society

Page: 1 2

Related medicine news :

1. NJIT chemistry professor edits text outlining best laboratory practices
2. Changing chemistry helps explain estrogen threat to the heart
3. Sealing corneal incisions with a drop of chemistry, BU researchers develop gel for cataract surgery
4. Herbal supplements testing topic of discussion at chemistry meeting March 30
5. Hopkins Peter Agre receives 2003 Nobel Prize in chemistry
6. Three Abbott chemists honored as Heroes for development of HIV therapy for children
7. Oregon State chemist wins national award for synthesizing molecules in nature
8. Chicago chemist wins national award for insights into how cells communicate
9. Irvine chemist wins national award for new drug techniques
10. Chicago chemist wins national award for new ways to make drug candidates
11. Illinois chemist wins national award for new drug research

Post Your Comments:

(Date:6/27/2016)... ... June 27, 2016 , ... ... industry today announced its strategic partnership with Connance, a healthcare industry leader ... two companies’ proven, proprietary technology combine to provide health systems, hospitals and ...
(Date:6/26/2016)... ... June 27, 2016 , ... Quality metrics are proliferating in ... ways they remain in the eye of the beholder, according to experts who offered ... The American Journal of Managed Care. For the full issue, click here . ...
(Date:6/26/2016)... ... ... PawPaws brand pet supplements owned by Whole Health Supply is ... of felines. The formula is all-natural and is made from Chinese herbs that have ... Kidney Support Supplement Soft Chews are Astragalus Root Extract and Rehmannia Root Extract ...
(Date:6/25/2016)... ... 2016 , ... Experts from the American Institutes for Research ... June 26-28, 2016, at the Hynes Convention Center in Boston. , AIR experts ... planning, healthcare costs and patient and family engagement. , AIR researchers will be ...
(Date:6/25/2016)... ... 2016 , ... "With 30 hand-drawn hand gesture animations, FCPX users can easily ... of Pixel Film Studios. , ProHand Cartoon’s package transforms over 1,300 hand-drawn pictures ... . Simply select a ProHand generator and drag it above media or text in ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... 2016  MedSource announced today that it has ... solution of choice.  This latest decision demonstrates MedSource,s ... their clients by offering a state-of-the-art electronic data ... nowEDC as the EDC platform of choice in ... "nowEDC has long been a preferred EDC platform ...
(Date:6/23/2016)... -- In a startling report released today, National Safety Council ... comprehensive, proven plan to eliminate prescription opioid overdoses. Prescription ... are tackling the worst drug crisis in recorded U.S. history, assigned ... Kentucky , New Mexico , ... 28 failing states, three – Michigan , ...
(Date:6/23/2016)... 23, 2016 Research and Markets has ... 52" report to their offering. ... creates a favourable commercial environment for MedImmune to enter. The ... that will serve to drive considerable growth for effective anti-influenza ... to cap sales considerably, but development is still in its ...
Breaking Medicine Technology:
Cached News: