HOME >> MEDICINE >> NEWS
Winning the battle of the bulge: We're a scrimmage closer to victory

ST. LOUIS -- Saint Louis University researchers believe they've won a major skirmish in the battle of the bulge, and their findings are published in the May issue of Diabetes.

"We figured out how obesity occurs," says William A. Banks, M.D., professor of geriatrics in the department of internal medicine and professor of pharmacological and physiological science at Saint Louis University School of Medicine. "The next step is coming up with the solution."

The scientists used mice to look at how leptin, a hormone secreted by fat cells that tells us to stop eating, gets into the brain. They found that in obese mice, high triglycerides, a type of fat in the bloodstream, prevents leptin from getting into the brain, where it can do its work in turning off feeding and burning calories.

"High triglycerides are blocking the leptin from getting into the brain. If leptin can't get into the brain, it can't tell you to stop eating," says Banks, who is principal investigator and a staff physician at Veterans Affairs Medical Center in St. Louis.

"This is a big deal. We now know what is keeping leptin from getting to where it needs to do its work."

Paradoxically high triglycerides occur in both fat and starving animals and make the brain think the body's starving so the animal keeps eating, which makes it gain more weight.

"We figured out why the troops aren't getting to the front. There is all of this leptin in the blood but it isn't getting to the brain because triglyerides are impairing the transportation system.

"We feel that we now understand what part of the system is broken - why leptin isn't working. We have a better understanding of why people are becoming obese," Banks says.

The research points scientists to a new direction in solving the obesity epidemic.

"Lowering triglyceride levels may very well be a big part of the answer," Banks says. "This is a reasonable deduction that should be tested."
'"/>

Contact: Nancy Solomon
solomonn@slu.edu
314-977-8017
Saint Louis University
27-Apr-2004


Page: 1 2

Related medicine news :

1. Chemists synthesize molecule that helps body battle cancers, malaria
2. Abandoned bones suggest TB wiped out leprosy in battle of killer diseases
3. Mayo Clinic recommends broadening treatment to battle recurrence of endometrial cancer
4. University of Manchester uses crystals to help battle deadly diseases
5. Study: Brain battles itself over short-term rewards, long-term goals
6. UCSD partners with Peru in NIH grant to battle malaria, worlds number 2 killer
7. New molecule may be basis for drugs that battle overeating and drug dependency
8. Univeristy of Utah anesthesiologists on front lines in battle against post-operative pain
9. Space science joins battle against cancer
10. Book explores how children use imagination to battle chronic illness
11. Researchers battle drug-resistant HIV on promising new ground

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Winning the battle the bulge scrimmage closer victory

(Date:5/3/2015)... It is not too late to register to take part ... Lissa Anne Been in Arnold, Missouri on May 9, 2015. ... honor her loving memory. It has benefited the renowned Brain Aneurysm ... 37, Lissa suffered a brain aneurysm . After two operations ... event is designed to serve as a remembrance of her and ...
(Date:5/2/2015)... Ticket Down has secured additional inventories of authentic ... event today, Saturday, May 2nd at the MGM Grand Garden ... able to secure tickets for both the actual fight and ... have wanted for more than five years was finally been ... step inside the ring to fight Manny “Pac-Man” Pacquiao in ...
(Date:5/2/2015)... ProText Kinetic 2 is a set of typography ... X. ProText Kinetic 2 features 40 animation presets ... X . Easily create interactive text videos without having ... Kinetic 2. , Using ProText Kinetic is as easy as ... presets in the FCPX timeline. Playback the default animation ...
(Date:5/2/2015)... Peachtree Audio ” was featured on NewsWatch as part ... and coolest technology products available to consumers. Scott Steinberg, ... the review and shared with viewers how this is ... important part of people’s lives – and as such, ... Peachtree Audio does just that with high-end audio equipment ...
(Date:5/2/2015)... 02, 2015 As a nonsurgical ... of the face, neck and décolleté, radiofrequency energy ... real potential for the success of vulvovaginal rejuvenation. ... Clinical Advisory Council, ThermiGyn’s Women’s Health Clinical Advisory ... concluded that ThermiGyn’s temperature controlled radio frequency, specifically ...
Breaking Medicine News(10 mins):Health News:Renowned Brain Aneurysm Foundation to Benefit from Arnold, Missouri’s 3rd Annual Brain Aneurysm Walk in Memory of Lissa Anne Been 2Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 2Health News:Cheap Floyd Mayweather vs. Manny Pacquiao Tickets: Ticket Down Has Last Minute Tickets for Mayweather vs. Pacquiao at the MGM Grand Garden Arena in Las Vegas 3Health News:Pixel Film Studios Announced the Release of Protext Kinetic 2 for FPCX. 2Health News:Affordable High-End Audio Equipment was Featured on NewsWatch Television 2Health News:Study Demonstrates Efficacy of Temperature Controlled Radiofrequency for Vulvovaginal Laxity 2Health News:Study Demonstrates Efficacy of Temperature Controlled Radiofrequency for Vulvovaginal Laxity 3
(Date:5/1/2015)... 2015  Legendary actor and director Danny Glover ... campaign designed to educate and encourage patients with neurologic ... Affect (PBA) and to speak with their physician. The ... the ability to cry and laugh on cue and ... by people living with PBA episodes. While ...
(Date:5/1/2015)... 1, 2015  Boston Scientific Corporation (NYSE: BSX ... momentum and long-term growth strategies at a meeting with ... City . President and Chief Executive Officer ... company has to bring forward meaningful innovation to transform ... deliver shareholder value. "We are focused ...
(Date:5/1/2015)... 2015  Misonix, Inc. (NASDAQ: MSON ), ... and markets innovative therapeutic ultrasonic products for spine ... laparoscopic surgery and other surgical applications, announced today ... third quarter fiscal year 2015 on Thursday, May ... call that same day, Thursday, May 7, 2015, ...
Breaking Medicine Technology:Danny Glover Joins PBA Facts Campaign, to Educate and Build Awareness of Pseudobulbar Affect (PBA), a Little Known but Widespread Neurologic Condition 2Danny Glover Joins PBA Facts Campaign, to Educate and Build Awareness of Pseudobulbar Affect (PBA), a Little Known but Widespread Neurologic Condition 3Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 2Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 3Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 4Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 5Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 6Boston Scientific Outlines Growth And Expansion Strategy At 2015 Investor Day 7Misonix, Inc. To Report Third Quarter Fiscal Year 2015 Financial Results On Thursday, May 7, 2015 2
Cached News: