HOME >> MEDICINE >> NEWS
Winning the battle of the bulge: We're a scrimmage closer to victory

ST. LOUIS -- Saint Louis University researchers believe they've won a major skirmish in the battle of the bulge, and their findings are published in the May issue of Diabetes.

"We figured out how obesity occurs," says William A. Banks, M.D., professor of geriatrics in the department of internal medicine and professor of pharmacological and physiological science at Saint Louis University School of Medicine. "The next step is coming up with the solution."

The scientists used mice to look at how leptin, a hormone secreted by fat cells that tells us to stop eating, gets into the brain. They found that in obese mice, high triglycerides, a type of fat in the bloodstream, prevents leptin from getting into the brain, where it can do its work in turning off feeding and burning calories.

"High triglycerides are blocking the leptin from getting into the brain. If leptin can't get into the brain, it can't tell you to stop eating," says Banks, who is principal investigator and a staff physician at Veterans Affairs Medical Center in St. Louis.

"This is a big deal. We now know what is keeping leptin from getting to where it needs to do its work."

Paradoxically high triglycerides occur in both fat and starving animals and make the brain think the body's starving so the animal keeps eating, which makes it gain more weight.

"We figured out why the troops aren't getting to the front. There is all of this leptin in the blood but it isn't getting to the brain because triglyerides are impairing the transportation system.

"We feel that we now understand what part of the system is broken - why leptin isn't working. We have a better understanding of why people are becoming obese," Banks says.

The research points scientists to a new direction in solving the obesity epidemic.

"Lowering triglyceride levels may very well be a big part of the answer," Banks says. "This is a reasonable deduction that should be tested."
'"/>

Contact: Nancy Solomon
solomonn@slu.edu
314-977-8017
Saint Louis University
27-Apr-2004


Page: 1 2

Related medicine news :

1. Chemists synthesize molecule that helps body battle cancers, malaria
2. Abandoned bones suggest TB wiped out leprosy in battle of killer diseases
3. Mayo Clinic recommends broadening treatment to battle recurrence of endometrial cancer
4. University of Manchester uses crystals to help battle deadly diseases
5. Study: Brain battles itself over short-term rewards, long-term goals
6. UCSD partners with Peru in NIH grant to battle malaria, worlds number 2 killer
7. New molecule may be basis for drugs that battle overeating and drug dependency
8. Univeristy of Utah anesthesiologists on front lines in battle against post-operative pain
9. Space science joins battle against cancer
10. Book explores how children use imagination to battle chronic illness
11. Researchers battle drug-resistant HIV on promising new ground

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Winning the battle the bulge scrimmage closer victory

(Date:3/5/2015)... At the 7th Annual Mississippi Addiction Conference ... met today in Jackson, Mississippi to listen to keynote ... numerous respected speakers will be William S. Jacobs, ... pain medications have had in today’s opiate overdose and ... is hard to believe that much of the current ...
(Date:3/5/2015)... University of Western States (UWS), ... has launched a new center of excellence to ... Northwest Center for Lifestyle and Functional Medicine aim ... and conduct research in the areas of lifestyle ... The center will target efforts on the UWS ...
(Date:3/5/2015)... NY (PRWEB) March 05, 2015 Dr. ... Surgeon ( http://www.orthopedicsurgeonnyc.com ) has been named by ... New York Metro area. Dr. Glashow has been selected ... authoritative guide to the top specialty care doctors in ... The prestigious Castle Connolly program, which carefully screens and ...
(Date:3/5/2015)... 05, 2015 Today, Earth Source ... on 100% pollution-free electricity through a partnership with ... As an Arcadia Power Clean Energy Partner, ESO ... Power Partnership requirements, joining national brands such as ... clean energy. Earth Source Organics joins a growing ...
(Date:3/5/2015)... Think it’s tough to get kids to ... them to brush their teeth. That’s a finding from a ... Delta Dental(1) in conjunction with National Parenting Month in March. ... kids to brush their teeth is one of the most ... higher than getting children to eat vegetables regularly (42 percent) ...
Breaking Medicine News(10 mins):Health News:National Addiction Treatment Expert William S. “Bill” Jacobs, Md Speaks At Prestigious 7th Annual Mississippi Addiction Conference 2Health News:National Addiction Treatment Expert William S. “Bill” Jacobs, Md Speaks At Prestigious 7th Annual Mississippi Addiction Conference 3Health News:University of Western States Launches Northwest Center for Lifestyle and Functional Medicine 2Health News:Dr. Jonathan Glashow, NYC Orthopedic Surgeon, Named Top Doctor: New York Metro Area 2Health News:Earth Source Organics to Run on Clean Energy from Arcadia Power 2Health News:Delta Dental Survey Says Parents Have Harder Time Getting Kids to Brush than to Eat Vegetables 2Health News:Delta Dental Survey Says Parents Have Harder Time Getting Kids to Brush than to Eat Vegetables 3
(Date:3/5/2015)... , March 5, 2015  ContraVir Pharmaceuticals, Inc. (NASDAQ: ... the development and commercialization of targeted antiviral therapies, announced ... Annual ROTH Conference, to be held March 8-11, ... James Sapirstein , Chief Executive Officer, ... his live presentation and will be available to participate ...
(Date:3/5/2015)... Calif. , March 5, 2015  Asterias Biotherapeutics, ... the emerging field of regenerative medicine, announced today that ... the nation,s top rehabilitation hospitals for spinal cord injury ... 1/2a clinical trial of AST-OPC1 (oligodendrocyte progenitor cells) in ... spinal cord injury (SCI). The Phase ...
(Date:3/5/2015)... YORK and VANCOUVER, British Columbia ... (CSE: BUX FSE: 20B OTCQB: BMKDF) -- The ultimate ... an assay that is capable of detecting tumors before ... forty years, the development of such an assay has ... in academia and industry. Although many breakthrough diagnostics have ...
Breaking Medicine Technology:ContraVir to Present at 27th Annual ROTH Conference 2Asterias Biotherapeutics Initiates Patient Enrollment for Phase 1/2a Clinical Trial of AST-OPC1 in Newly Injured People with Complete Cervical Spinal Cord Injury 2Asterias Biotherapeutics Initiates Patient Enrollment for Phase 1/2a Clinical Trial of AST-OPC1 in Newly Injured People with Complete Cervical Spinal Cord Injury 3Asterias Biotherapeutics Initiates Patient Enrollment for Phase 1/2a Clinical Trial of AST-OPC1 in Newly Injured People with Complete Cervical Spinal Cord Injury 4New Cancer Diagnostic Primed to Change the Industry 2New Cancer Diagnostic Primed to Change the Industry 3New Cancer Diagnostic Primed to Change the Industry 4
Cached News: