HOME >> MEDICINE >> NEWS
Wistar Scientist Awarded American Cancer Society Grant For Study Of Tumor,,Suppressor Proteins

Philadelphia -- Wistar scientist, Ronen Marmorstein, Ph.D., has been awarded a $322,000 three-year grant from the American Cancer Society. The funds will be used to support his research into the structure and function of proteins involved in the development of a variety of human cancers.

Lung, breast, brain, bone, skin, bladder, kidney and ovarian cancers all share a common characteristic -- the gene regulating the activity of P16INK4, which fastens itself to the CDK4 inhibitory protein, is either deleted or mutated. The consequence of this genetic alteration is that the P16INK4 protein does not interfere as it should with tumor growth.

"Because of its key role in the development of tumors," explains Dr. Marmorstein, "the CDK4 protein is an excellent target for anti-cancer therapies." His laboratory's findings on the structural properties of the P16INK4 protein are expected to provide a framework for the design of P16INK4 imitations that can be used in the treatment of cancers caused by abnormal CDK4 activity.

The Wistar Institute, established in 1892, was the first independent medical research facility in the country. For more than 100 years, Wistar scientists have been making history and improving world health through their development of vaccines for diseases that include rabies, German measles, infantile gastroenteritis (rotavirus), and cytomegalovirus; discovery of molecules like interleukin-12, which are helping the immune system fight bacteria, parasites, viruses and cancer; and location of genes that contribute to the development of diseases like breast, lung and prostate cancer. Wistar is a National Cancer Institute Cancer Center.


'"/>

Contact: Diana Cutshall
dcutshall@wista.wistar.upenn.edu
(215) 898-3716
The Wistar Institute
22-May-1998


Page: 1

Related medicine news :

1. Director of AIDS Research Center to give Wistar Institutes 1999 Jonathan Lax Memorial Lecture
2. Wistar scientist receives Arthritis Foundation award
3. Wistar Institute Facility distinguished as center of excellence by Ben Franklin Technology PArtners of Southeastern Pennsylvania for second year
4. National Cancer Institute awards Wistar Institute $6.6 million for melanoma research
5. Wistar scientist awarded American Cancer Society grant for research on tumor killing cells
6. Research Grant To Wistar Institute Involves Linda Creed Breast Cancer Foundation In Breast Cancer Research
7. Lupus Foundation Of America Awards Summer Internship To Student Working At Wistar Institute
8. Scientist works on innovative treatments for brain tumors
9. Scientists replicate hepatitis C virus in laboratory
10. Scientists identify brain regions that decide where we look
11. Scientists uncover new mechanism for the amygdala in fear recognition

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/14/2020)... ... February 14, 2020 , ... ... , further strengthening the company’s support for healthcare organizations using Amazon Web Services ... have the resources or experience to do so,” explained Cloudticity Founder & CEO, ...
(Date:2/13/2020)... ... February 13, 2020 , ... The ... committed to achieving health equity for all Americans will unveil its new Status ... 26th event at the National Press Club. , The event will feature a ...
(Date:2/13/2020)... ... 13, 2020 , ... The largest fertility center in the ... Fairfax, Fredericksburg, Leesburg, and Woodbridge, as well as two locations in the District, ... named as Top Docs for Infertility by Northern Virginia Magazine. , Each ...
(Date:2/13/2020)... HILLS, Calif. (PRWEB) , ... February 13, 2020 , ... ... and cosmetic procedures that people will be discussing in 2020. It also reports on ... cosmetic and surgical procedures. Dr. Jazayeri says that his patients are increasingly knowledgeable and ...
(Date:2/11/2020)... ... 11, 2020 , ... Soterius, Inc., a global provider of ... a new, significantly larger business premises in Lawrenceville, NJ. The move supports the ... of digital technology platforms. , “As our customer base and offerings continue to ...
Breaking Medicine News(10 mins):
(Date:2/19/2020)... ... February 19, 2020 , ... ... the best colleges and universities for people with disabilities. , The Edvocate ... people with disabilities succeed in higher education. AIC placed in the top ten ...
(Date:2/15/2020)... , ... February 14, 2020 , ... Dr. Ray Lopez, ... Haute Beauty Network. , The Haute Beauty Network, well known for its exclusive and ... foot and ankle and our newest addition to the Haute Beauty members-only network. , ...
(Date:2/14/2020)... ... February 14, 2020 , ... American International College (AIC) will ... 2020, the first of its kind in this region. , The 30-credit, ... cannabis industry and will provide students with an understanding of the science, business, ...
Breaking Medicine Technology:
Cached News: