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Women with PCOS and their siblings with hormone problems have same gene defect

naif said.

PCOS is a complex disorder that affects nearly 10 percent of premenopausal women and is associated with elevated levels of androgens, as well as irregular menstrual periods and reproductive problems. Other symptoms of PCOS include obesity, excess hair on the face and body, male-pattern baldness and severe, chronic acne.

Many women with PCOS are insulin-resistant, a condition that raises the level of insulin circulating in the body and is a precursor to type 2 diabetes. In fact, women with PCOS have seven times the risk of other women for developing adult-onset diabetes, which in turn greatly increases their chance of having cardiovascular disease, stroke and kidney problems. Dunaif's research also has shown that PCOS is an important risk factor for the adult form of diabetes in teenaged girls.


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Contact: Elizabeth Crown
e-crown@northwestern.edu
312-503-8928
Northwestern University
12-Aug-2002


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