Young breast cancer patients who chose lumpectomies need indefinite follow-up

Young breast cancer patients who have breast conserving treatment are at higher risk of recurrence many years later than are older women who have the same treatment or women who have mastectomies, according to research published today (Monday 3 November) in Annals of Oncology.[1]

The researchers are definitely not saying that breast conservation treatment should be used less in younger patients, but they are saying that extra care should be taken with this treatment in younger women and that they should be followed up indefinitely. They also emphasised that the patients in their research study were diagnosed in the 1970s and therefore did not receive tamoxifen the anti-oestrogen drug now widely given to women whose tumours are hormone-sensitive.

The study, by a team from the Institut Gustave-Roussy and INSERM in Villejuif, France, followed 179 patients recruited to a trial in the 1970s for a mean duration of 22 years after diagnosis the longest follow-up of any trial comparing lumpectomy with breast irradiation against mastectomy. The 91 mastectomy and 88 conservation treatment patients were comparable in terms of age, tumour size (under 20 mm) and grade and the number of negative lymph nodes.

To verify the validity of their findings the researchers then analysed the results of 1,847 patients from the Institut Gustave-Roussy's database (632 who had conservation surgery and 1,215 who had mastectomies) who also had small tumours (under 25mm) and had followed a comparable radiotherapy protocol.

"What we found in the trial of 179 patients was that there was no difference over time on survival or on metastasis (secondary cancer)," said lead researcher Dr Rodrigo Arriagada. "The risk of local recurrence was actually five-fold less in the breast conservation patients during the first five years than in the mastectomy group. However, after five years it was 12-fold greater. The age range of the patients who developed local recurrence was s

Contact: Margaret Willson
European Society for Medical Oncology

Page: 1 2 3

Related medicine news :

1. 2005 Young Investigator Award
2. Study: Young adults can be motivated to eat fruits, veggies
3. Young blood revives aging muscles, Stanford researchers find
4. Young people face increasing risk of suicide in Scotland
5. Younger children in the child welfare system could benefit from specialty mental health services
6. Younger men lead surge in Viagra use, study reveals
7. Young breast cancer survivors suffer more long-term after effects
8. 2004 Young Investigator Award to Fleming
9. Young people prone to type 2 diabetes exhibit alterations in mitochondrial activity
10. Young men with conduct disorders are more likely to carry guns
11. Young adult fitness protects heart health in middle age

Post Your Comments:

(Date:1/7/2020)... ... 2020 , ... R3 Stem Cell is now offering access to all regenerative ... available 24/7 and includes all the stem cell and exosome courses. , For several ... person. For the online regenerative training courses, R3 assembled all of the presentations and ...
(Date:1/5/2020)... ... 2020 , ... NJ Top Dentist, Dr. Irvin B. Sherman has been reviewed ... infants, children, teens and the special needs patient. The practice is located in Avon ... health. , Dr. Sherman and his practice will be addressing issues that mothers are ...
(Date:1/3/2020)... ... 02, 2020 , ... Isagenix International , a global ... round of U.S. finalists for its annual total-body transformation program, the IsaBody ... Ashley Pederson of St. Paul, Minnesota; Kim Nase of Lynnwood, Washington; Tim Brown ...
(Date:1/3/2020)... ... January 03, 2020 , ... Liz Barlowe, MA, CMC ... Directors (ALCA). Aging Life Care Professionals® have advanced degrees and are experts in ... disabled, and work with the family to provide recommendations for needed goods and ...
(Date:1/2/2020)... PLEASANTON, Calif. (PRWEB) , ... January 02, 2020 ... ... (NYSE:TFX) focused on addressing unmet needs in the field of urology, today announced ... as a UroLift® Center of Excellence. The designation recognizes that Dr. Jain has ...
Breaking Medicine News(10 mins):
(Date:1/7/2020)... (PRWEB) , ... January 07, 2020 , ... ... first calibration-free blood pressure (BP) sensor system for integration in hearables and wearables. ... device and consumer electronics manufacturers for inclusion in their products. Embedded in an ...
(Date:1/7/2020)... FALLS CHURCH, Va. (PRWEB) , ... January 07, ... ... QMS-PMS Focus, An FDAnews Webinar, Tuesday, Jan. 21, 2020, 11:00 a.m.-12:30 p.m. EST, ... diagnostic (IVD) industry market globally. It is the only market with a 20 ...
(Date:1/3/2020)... Texas (PRWEB) , ... January 03, 2020 , ... In ... provide free dental services for low-income, underinsured individuals at its Burleson, TX office on ... and x-rays, fillings , cleanings and extractions . For more ...
Breaking Medicine Technology:
Cached News: