A new metal detector to study human disease

Zinc may be a familiar dietary supplement to millions of health-conscious people, but it remains a mystery metal to scientists who study zincs role in Alzheimers disease, stroke and other health problems.

They are just beginning to fathom how the body keeps levels of zinc under the precise control that spells the difference between health and disease.

Researchers now have developed a biochemical metal detector to help crack the mystery. It is a biosensor that has yielded the first measurements of the tiny amounts of zinc ordinarily present inside living cells.

The study appears in the current issue of ACS Chemical Biology, the newest of 34 journals published by the American Chemical Society, the worlds largest scientific organization.

It was conducted by Rebecca A. Bozym and Richard B. Thompson, Ph.D. of the department of biochemistry and molecular biology, University of Maryland School of Medicine, Baltimore, and Andrea K. Stoddard and Carol A. Fierke, Ph.D. of the Department of Chemistry, University of Michigan, Ann Arbor.

The question of how much zinc is available in a cell has emerged at the forefront of chemical biology, Amy R. Barrios, Ph.D., of the University of Southern California, Los Angeles, wrote in an accompanying Point of View in ACS Chemical Biology.

Barrios described the new research as a critical step forward, and predicted many more exciting breakthroughs in measuring levels of metals in human cells.

Just 2-3 grams of zinc (the weight of a penny coin) exist in the entire human body. The metal is a key building block in enzymes and other substances involved in functioning of the nervous system, the immune response, and the reproductive system.

We believe this new technique can help us understand how zinc is involved in plaque formation in Alzheimers disease, how prolonged seizures or stroke kill brain cells, and how the cell normally

Contact: Michael Bernstein
American Chemical Society

Page: 1 2

Related medicine news :

1. Researchers link metal ions to neurodegenerative disease
2. Bare-metal stents are better for some heart patients
3. Drug-eluting stents outperform radiation treatment for coronary restenosis in bare metal stents
4. MIT thinks small to find safer metals
5. Journal of Alzheimers Disease is devoted to metal ions and neurodegenerative diseases
6. Watching metals melt, nanometer-scale views inside cells
7. New accreditation program for radiation detector labs
8. Anthrax detector developed
9. Early myocardial enhancement defects on multidetector CT predicts future myocardial viability
10. Breast cancer detector that uses electricity instead of X-rays under study
11. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals

Post Your Comments:

(Date:11/26/2015)... ... 2015 , ... The Catalent Applied Drug Delivery Institute today ... dose form selection in early phase drug development. The first of these is ... together the UK’s emerging life sciences companies, corporate partners, and investors, at Milton ...
(Date:11/26/2015)... ... November 26, 2015 , ... PRMA Plastic Surgery is updating ... our surgeons performed their 6,000th free flap breast reconstruction surgery! , “What an accomplishment ... day excited to rebuild lives and it’s an honor to have served all of ...
(Date:11/26/2015)... ... 26, 2015 , ... Pixel Film Studios brings Final Cut ... Vintage. This newly styled ProTrailer pack comes with 30 all-new vintage-inspired designs, with ... users limitless opportunities to stylize and create designs quickly and easily, all within ...
(Date:11/26/2015)... , ... November 26, 2015 , ... Indosoft Inc., developer ... of an application server to improve system efficiency and reliability. , The new Q-Suite ... of these standards, the system avoids locking itself into a specific piece of software ...
(Date:11/25/2015)... ... November 25, 2015 , ... As part of a global ... attracts volunteers together who want to combine talents and resources to help create ... the process. The non-profit launched its first major fundraiser on November 6, 2015 ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... , November 26, 2015 ... addition of the "2016 Future Horizons ... of Abuse Testing Market: Supplier Shares, Country ... report to their offering. --> ... the "2016 Future Horizons and Growth ...
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Drug Monitoring (TDM) Market: Supplier Shares, ... Opportunities"  report to their offering.  ... the addition of the  "2016 Future ...
(Date:11/26/2015)... Nov. 26, 2015 Research and Markets ... the "2016 Future Horizons and Growth Strategies ... Supplier Shares, Country Segment Forecasts, Competitive Intelligence, Emerging ... --> --> This ... the Italian therapeutic drug monitoring market, including emerging ...
Breaking Medicine Technology:
Cached News: