HOME >> MEDICINE >> NEWS
A potential new affordable diagnostic test for TB

A technique that identifies proteins* in the blood particular to tuberculosis (TB) could be used to develop a new diagnostic test for the disease, according to an Online/Article published today (Thursday September 14, 2006) by The Lancet.

At present sputum smear microscopy is often the only available and affordable diagnostic test in most developing countries where TB is endemic, but at best it can detect 50-60% of positive cases. This test, which looks for Mycobacterium tuberculosis, is the diagnostic gold standard as it is sensitive and specific in cases of smear positive tuberculosis but it takes 2-6 weeks to give a result and is not routinely used in countries with high prevalence of TB because of cost.

Sanjeev Krishna (St George's Hospital Medical School, London, UK) and colleagues used a new technique called SELDI-ToF, ** to identify diagnostic combinations of proteins in the blood for TB. They used blood from patients with the disease and controls from several different countries, including the UK, The Gambia, Uganda and Angola, representing at least four ethnic backgrounds.

Using a combination of four biomarkers from this technique, they achieved a diagnostic accuracy for TB of up to 78%. The authors identified two of the possible 20 most discriminatory proteins that could be adapted for use in the field.


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
13-Sep-2006


Page: 1

Related medicine news :

1. DNA vaccine against multiple sclerosis appears safe, potentially beneficial
2. Electric fields have potential as a cancer treatment
3. STAMP system can help professionals to identify potentially violent individuals
4. AMPAKINE compounds a new potential treatment for respiratory depression
5. Herb shows potential to reduce cancer-related fatigue
6. Clinical data suggest potential versatility of ALIMTA-based regimens in lung cancer
7. Women with breast cancer do not get potentially life-saving information, survey reveals
8. Eating cured meats frequently can lead to lower lung function and potential COPD
9. Clinical studies evaluate potential treatments for mouth ulcers
10. Synthetic production of potential pharmaceuticals dramatically simplified by Scripps research team
11. Obesity and environmental chemicals -- New research probes potential link

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: potential new affordable diagnostic test for

(Date:5/5/2015)... The brains of people with type 1 diabetes ... information processing, according to research led by the ... , The findings indicate that clinicians should consider ... difficulties. If progressive, these changes could influence their ability ... National Institutes of Health (NIH), is online ...
(Date:5/5/2015)... Okyanos, the leader in cell ... study was conducted to determine the emotional impact and ... and sports-related injuries have had on those affected. The ... prevalent symptom reported at 73%, followed by 66% of ... bending over. Over half of respondents, 56%, said they ...
(Date:5/5/2015)... Rare Genomics Institute (RG) today announced ... determining how crowdfunding can promote scientific research to help ... rare disease patients with access to state of the ... and help for payment of these services through grants, ... how crowdfunding will not only help raise much needed ...
(Date:5/5/2015)... On May, 5, 2015, My Positive Perspective host Jason Deierlein ... for youngsters to do this summer. As the episode began, ... starting a summer camp and how is it going to ... Upon a Party and I come to children’s birthday parties ... We play games, sing, and dance and have a great ...
(Date:5/5/2015)... New Jersey (PRWEB) May 05, 2015 ... today announced the launch of a new healthy cooking ... a season two semi-finalist on Bravo’s Top Chef, teamed ... that promote wellness and healthy living. In support ... enhanced Wellness Website and the videos will be showcased ...
Breaking Medicine News(10 mins):Health News:Accelerated Brain Aging in Type 1 Diabetes Related to Cognitive Complications 2Health News:Accelerated Brain Aging in Type 1 Diabetes Related to Cognitive Complications 3Health News:Accelerated Brain Aging in Type 1 Diabetes Related to Cognitive Complications 4Health News:Okyanos Study Finds Orthopedic Patients Plagued with Pain 2Health News:Okyanos Study Finds Orthopedic Patients Plagued with Pain 3Health News:Rare Genomics Institute to Study Impact of Crowdfunding on Rare Diseases 2Health News:My Positive Perspective Hosts Episode Informing People of a True Princess Summer Camp With Irene Rose 2Health News:Barnabas Health Teams Up With Celebrity Chef Sam Talbot To Launch "Life Is Better Healthy" Cooking Video Series 2Health News:Barnabas Health Teams Up With Celebrity Chef Sam Talbot To Launch "Life Is Better Healthy" Cooking Video Series 3
(Date:5/5/2015)...  Image Stream Medical, a leader in OR video ... of the largest group purchasing organizations, serving four out ... of the three-year agreement, Image Stream,s portfolio of EasySuite™ ... available to MedAssets members beginning on July 1, 2015. ... CEO Eddie Mitchell said, ...
(Date:5/5/2015)... 5, 2015 E-QURE (Electric Quick ... a premier provider of innovative medical devices in the ... update to shareholders and the investment community, covering 2014 ... of the proprietary Bioelectrical Signal Therapy™ (BST) Device for ... S-1, as well as its plans for commercialization and ...
(Date:5/5/2015)... Faced with fast economy and population growth, an aging population, ... medical device industry has been growing rapidly in recent ... Beijing , Shanghai , ... the entry of a large number of medical device companies ... cities increasingly saturated. How do medical device enterprises look for ...
Breaking Medicine Technology:Image Stream Medical Announces Agreement with MedAssets 2E-QURE Corp. Issues 2014 - 2015 Update to Shareholders 2E-QURE Corp. Issues 2014 - 2015 Update to Shareholders 3E-QURE Corp. Issues 2014 - 2015 Update to Shareholders 4E-QURE Corp. Issues 2014 - 2015 Update to Shareholders 5MEDITEXPO JIANGSU 2015 is to Help Medical Device Companies Explore Business Opportunities in Wider Markets 2MEDITEXPO JIANGSU 2015 is to Help Medical Device Companies Explore Business Opportunities in Wider Markets 3MEDITEXPO JIANGSU 2015 is to Help Medical Device Companies Explore Business Opportunities in Wider Markets 4
Cached News: