HOME >> MEDICINE >> NEWS
A potential new affordable diagnostic test for TB

A technique that identifies proteins* in the blood particular to tuberculosis (TB) could be used to develop a new diagnostic test for the disease, according to an Online/Article published today (Thursday September 14, 2006) by The Lancet.

At present sputum smear microscopy is often the only available and affordable diagnostic test in most developing countries where TB is endemic, but at best it can detect 50-60% of positive cases. This test, which looks for Mycobacterium tuberculosis, is the diagnostic gold standard as it is sensitive and specific in cases of smear positive tuberculosis but it takes 2-6 weeks to give a result and is not routinely used in countries with high prevalence of TB because of cost.

Sanjeev Krishna (St George's Hospital Medical School, London, UK) and colleagues used a new technique called SELDI-ToF, ** to identify diagnostic combinations of proteins in the blood for TB. They used blood from patients with the disease and controls from several different countries, including the UK, The Gambia, Uganda and Angola, representing at least four ethnic backgrounds.

Using a combination of four biomarkers from this technique, they achieved a diagnostic accuracy for TB of up to 78%. The authors identified two of the possible 20 most discriminatory proteins that could be adapted for use in the field.


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
13-Sep-2006


Page: 1

Related medicine news :

1. DNA vaccine against multiple sclerosis appears safe, potentially beneficial
2. Electric fields have potential as a cancer treatment
3. STAMP system can help professionals to identify potentially violent individuals
4. AMPAKINE compounds a new potential treatment for respiratory depression
5. Herb shows potential to reduce cancer-related fatigue
6. Clinical data suggest potential versatility of ALIMTA-based regimens in lung cancer
7. Women with breast cancer do not get potentially life-saving information, survey reveals
8. Eating cured meats frequently can lead to lower lung function and potential COPD
9. Clinical studies evaluate potential treatments for mouth ulcers
10. Synthetic production of potential pharmaceuticals dramatically simplified by Scripps research team
11. Obesity and environmental chemicals -- New research probes potential link

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/2/2016)... ... 2016 , ... In honor of National Physical Fitness and Sports Month in ... their fitness journey on social media. , The foot care company, which specializes ... product voucher each week during May to one winner. , “Whether the goal is ...
(Date:5/2/2016)... ... May 02, 2016 , ... East Los Angeles dentist ... patients can visit Dr. Assili to receive any dental extraction treatment for $40 off ... expires June 30, 2016. With the lower price, patients can more easily afford extractions ...
(Date:5/2/2016)... Orange County, CA (PRWEB) , ... May 02, 2016 , ... ... study now linking dental health and cognitive decline. According to the research, which was ... seniors have some degree of cognitive decline, and about 5.4 million Americans have Alzheimer’s ...
(Date:5/2/2016)... ... 2016 , ... Pregnancy Awareness Month offers a great time to get familiar ... you are ready to have a baby, it’s best to get started before age ... your Personal Conception & Pregnancy Organizer, written for women who plan on becoming pregnant ...
(Date:5/2/2016)... ... ... Kulbersh of Carolina Facial Plastics isn’t surprised that Charlotte, NC, the city where he and ... Cities with the Highest Plastic Rates .” The other cities that made the list ... a survey by RealSelf and combining that data with the number of board-certified ...
Breaking Medicine News(10 mins):
(Date:4/29/2016)... Glycotope GmbH, a clinical-stage immuno-oncology company built ... Dr. Alfredo Zurlo as Chief Medical Officer. ... years clinical experience and a proven track record in ... at Mologen AG where he was Chief Medical Officer ... held various positions at F Hoffmann La Roche and ...
(Date:4/28/2016)... 28, 2016  While Abbott,s announced purchase of ... valve repair and stent business, healthcare research firm ... more firmly into patient monitoring.  Kalorama said that ... device areas, with double-digit growth expected the next ... Advanced Remote Patient Monitoring . Abbott Laboratories ...
(Date:4/28/2016)... Dr. ... und Stephen Schmidt werden Teil ... ein führender Anbieter cloudbasierter Softwarelösungen für den ... neue Führungskräfte zum Team Sicherheit und Pharmakovigilanz ... Erfahrungen mitbringen.  Dies wird die Geschäftseinheit Sicherheit ...
Breaking Medicine Technology:
Cached News: