evelopment of obesity provides a framework for evidence-based treatment the disease. As new and exciting research continues into the causes, prevention and treatments for obesity, the role played by the gastrointestinal (GI) tract is becoming more defined. This understanding will lead to novel endoscopic, pharmacological and nutritional therapies for obesity as well as changes in policies and societal practices related to obesity.

Due to the widespread effects of obesity on a persons health, it is urgent that the AGA Institute collaborates with other leading medical organizations to encourage a multidisciplinary approach to the treatment of our patients to most affectively address their health needs, said Dr. Kaplan.

The research found in this special issue of Gastroenterology was chosen to emphasize the multidimensional problems of obesity and to outline the integrated approach needed to understand the extent of the problem, causes and health and socioeconomic consequences of obesity. Several papers of note include:

• The Epidemiology of Obesity - Katherine M. Flegal, PhD, National Center for Health Statistics, and colleagues review the epidemiology of obesity, highlighting controversies surrounding adiposity (quality or state of being fat) measurement, ethnic differences, childhood obesity and diseases associated with obesity.
• "Gut Hormones and Appetite Control - Stephen R. Bloom, MD, Imperial College of London and colleagues review the role played by gut hormones in appetite and weight by regulating when and how much individuals eat for every meal.
• Obesity, Inflammation and Insulin Resistance - Steven E. Shoelson, MD, PhD, Joslin Diabetes Center and Harvard Medical School and colleagues discuss the potential roles for inflammation in the development of insulin resistance and type 2 diabetes.
• The Role of Obesity and Related Metabolic Disturbances in Cancers of the Colon, Prostate and Pancreas - Edwa
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Contact: Aimee Frank
media@gastro.org
301-941-2620
American Gastroenterological Association
14-May-2007


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