Accelerating weight loss may signal development of Alzheimer's disease

The slow, steady weight loss associated with aging may speed up prior to the onset of Alzheimer's disease and related dementias, according to an article in the September issue of Archives of Neurology, one of the JAMA/Archives journals.

Changes that occur with aging, such as reduced appetite and diminishing height, may induce weight loss in older adults, according to background information in the article. Alzheimer's disease has also been linked to age-related weight loss. Those in the late stages of the disease can lose up to 2 pounds per year; those who lose more weight are more likely to progress quickly and to be placed in a nursing home.

David K. Johnson, Ph.D., and colleagues at Washington University School of Medicine, St. Louis, studied weight loss before the development of dementia in 449 healthy adults (192 men, 257 women). At the beginning of the study and then yearly for an average of six years, the participants were assessed for dementia, weighed and asked questions about their medical history.

Over the course of the study, 125 participants developed dementia related to Alzheimer's disease. Those who did weighed about eight pounds less at the beginning of the study than those who did not develop Alzheimer's disease. In addition, "an acceleration in the rate of weight loss was a harbinger of the change from non-demented status to dementia of the Alzheimer's type," the authors write. "Participants lost about .6 pounds per year while without dementia, but one year before the first symptomatic detection of dementia of the Alzheimer's type, the rate of weight loss in individuals doubled to 1.2 pounds per year." This association held when the researchers controlled for other factors that might influence weight loss, including age, sex, health status, hypertension (high blood pressure) and stroke history.

It is unclear exactly why weight loss is associated with dementia, the authors write. Some have hypothesized tha

Contact: Michael Purdy
JAMA and Archives Journals

Page: 1 2

Related medicine news :

1. How to lose weight and not go hungry: HU researcher develops drug that mimics feeling of fullness
2. Born to lose: How birth weight affects adult health and success
3. Studies show role of age, gender, race and weight on cancer risk and treatment
4. Healthy body weight throughout adulthood may help delay disability
5. Full-term, low-birth-weight babies at significantly greater risk for early respiratory symptoms
6. Alzheimers weight gain initiative also improved patients intellectual abilities
7. Low physical activity can improve fitness levels for sedentary, overweight postmenopausal women
8. Calcium plus vitamin D supplements may help prevent weight gain in postmenopausal women
9. Eggs promote weight loss and help close nutrient consumption gap
10. Free weight training gets workers with rotator cuff injuries back on the job
11. Simple system accurately predicts weight-loss surgery risk

Post Your Comments:

(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: