HOME >> MEDICINE >> NEWS
American Thoracic Society publishes new statement on hepatotoxicity of antituberculosis therapy

The American Thoracic Society (ATS) has published a new statement on the pathogenesis, prevention and treatment of liver damage caused by anti-tuberculosis (TB) medications.

The statement, which appeared in the October 15 issue of the American Journal of Respiratory and Critical Care Medicine, gives a review of current national and international literature on drug-induced liver injury (DILI) or hepatotoxicity, a potential side effect of more than 700 drugs approved for use in the United States. The document also provides recommendations for minimizing a patient's risk of developing liver damage and identifies directions for future research.

"Hepatotoxicity has been a long-standing and often treatment-limiting concern for physicians caring for patients infected with active and latent TB," said Jussi J. Saukkonen, M.D., who chaired the statement writing committee, which included 12 members of the ATS Assembly on Microbiology, Tuberculosis and Pulmonary Infections.

The multi-disciplinary writing committee looked carefully at this issue in the new guidelines, which provide clinicians with all of the current evidence-based and clinical information available on identifying risk factors, recognizing symptoms, weighing the benefits with the risks and developing safe treatment programs.

As noted in "Treatment of Tuberculosis," a 2003 statement published by the ATS, Centers for Disease Control and Prevention and Infectious Diseases Society of America, some TB treatment regimens can infrequently cause serious damage to the liver, especially in people who chronically consume alcohol, have preexisting liver disease, are pregnant or who take other hepatotoxic medications.

Unlike the 2003 guidelines, which were much broader in scope, the new statement focuses solely on DILI related to TB medications. "To help clinicians understand and recognize DILI, we documented the metabolism of these drugs, mechanisms of injury and clin
'"/>

Contact: Suzy Martin
smartin@thoracic.org
212-315-8631
American Thoracic Society
7-Nov-2006


Page: 1 2 3

Related medicine news :

1. Test project of patient-centered medical home model endorsed by American College of Physicians
2. Drug-eluting stent controversy explored in the American Heart Hospital Journal
3. Highlights from the August 2007 Journal of the American Dietetic Association
4. American Cancer Society to hold third annual Virtual Relay For Life in Second Life
5. High-Need Physician Workforce Incentives Act endorsed by American College of Physicians
6. African-American men understimate risk of prostate cancer
7. Highlights from the June 2007 Journal of the American Dietetic Association
8. Susan G. Komen for the Cure and American Society of Clinical Oncology partner in national initiative
9. Limiting eligibility for medical studies can omit women and African-Americans
10. African-Americans perceive people with extreme health problems as less productive and valuable
11. News from American Psychiatric Association 2007 Annual Meeting

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/30/2021)... , ... March 29, 2021 , ... ... the 21st Century , A Virtual Workshop Presented by WCG FDAnews and Cerulean ... 4:30 pm EDT, https://wcg.swoogo.com/modern-sop-and-quality-systems , Are one’s SOPs written for the ...
(Date:3/30/2021)... ... March 29, 2021 , ... According to data released ... reproductive age (13-44) in need of publicly funded contraception live in counties impacted by ... Colorado’s 64 counties have lost some of their Title X resources. , The ...
(Date:3/30/2021)... ... March 29, 2021 , ... Health Literacy Innovations (HLI), a ... confusion due to low health literacy today announces a new partnership with the ... work with ACAP’s member Safety Net Health Plans, those that provide comprehensive health ...
(Date:3/30/2021)... ... ... Dr. Colin Campbell is proud to announce the 1 year anniversary in their new state ... internal medicine and is a primary care specialist who has been practicing for 23 years. ... keep South Jersey healthy one patient at a time. , “Over the past year, Dr. ...
(Date:3/30/2021)... ... March 30, 2021 , ... The COVID-19 ... and survivors; their families; and their caregivers. Crossroads4Hope is addressing the needs of ... emotional support system, MyGo2Support, which meets needs of people impacted by cancer, no ...
Breaking Medicine News(10 mins):
(Date:3/30/2021)... ... March 29, 2021 , ... The University of Texas Health Science Center ... San Antonio Multispecialty and Research Hospital, a destination center for research and treatment of ... In a nod to the COVID-19 pandemic, the ceremony was held virtually. , William ...
(Date:3/30/2021)... ... March 29, 2021 , ... Iora Health ... primary care, has partnered with Devoted Health , one of the fastest-growing ... across Maricopa County and provides seniors with the highest-quality care and experience possible, ...
(Date:3/30/2021)... CITY (PRWEB) , ... March 29, 2021 , ... ... has joined the Vaccine Credential Initiative (VCI), a group bringing together leading health ... record of vaccination status, based on open, interoperable standards. By joining the VCI ...
Breaking Medicine Technology:
Cached News: