HOME >> MEDICINE >> NEWS
Angioplasty reduces long-term cardiac risk among heart patients with 'silent' ischemia

When compared with intensive drug therapy, percutaneous coronary intervention (PCI, angioplasty) was more beneficial in reducing the long-term risk of major cardiac events among heart attack survivors with "silent ischemia", according to a study in the May 9 issue of JAMA.

Cardiac ischemia is caused by insufficient blood flow to the heart muscle tissue. Silent ischemia can occur without accompanying signs or symptoms of angina (chest pain due to inadequate supply of oxygen to the heart muscle), but can be detected by electrocardiogram (ECG) and other techniques. Silent ischemia has been shown to predict adverse prognosis in patients after myocardial infarction (MI, heart attack), coronary artery bypass graft surgery, and PCI, with or without stenting, according to background information in the article. However, the effect of PCI on the long-term prognosis of patients with silent ischemia after a heart attack is not known.

Paul Erne, M.D., of the Division of Cardiology, Kantonsspital Luzern, Luzern, Switzerland, and colleagues conducted a randomized, unblinded, controlled trial from May 2, 1991, to February 25, 1997, to determine whether PCI compared with drug therapy improves long-term outcome of asymptomatic patients with silent ischemia after a heart attack. A total of 201 patients with a recent heart attack, silent myocardial ischemia verified by stress imaging, and one- or two-vessel coronary artery disease took part in the study. Ninety-six patients underwent PCI, and 105 patients received intensive anti-ischemic drug therapy. All patients received 100 mg. per day of aspirin and a statin (cholesterol-lowering) drug. Follow-up ended on May 23, 2006.

Patients in the PCI group experienced 27 major adverse cardiac events during an average follow-up of 10.2 years. During the same period, 67 adverse cardiac events occurred in the anti-ischemic drug group. This corresponds to an absolute event reduction of 6.3 percent per year
'"/>

Contact: Paul Erne
Paul.Erne@ksl.ch
JAMA and Archives Journals
8-May-2007


Page: 1 2

Related medicine news :

1. Nonhormonal drug reduces hot flashes in men treated for prostate cancer
2. Circumcision reduces HIV infection risk
3. Retinol lotion reduces the fine wrinkles from natural aging of skin
4. Improving communication with families of dying patients reduces stress, anxiety and depression
5. New study: Pycnogenol reduces heart failure
6. Drinking farm milk reduces childhood asthma and allergies but raw consumption remains unsafe
7. Once-yearly treatment significantly reduces bone fractures in women with postmenopausal osteoporosis
8. Once-a-year drug reduces fractures from osteoporosis
9. Studies suggest investigational agent reduces disease activity in MS
10. Smoking ban dramatically reduces air pollution in Irish pubs
11. Penn researchers find treatment for MS also reduces vision loss in MS patients

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/17/2019)... ... ... Milwaukee-area dealership Hall Cars has hosted an annual event each fall for years in an ... Cancer,” entails that for every vehicle purchased from Sept. 17 to Nov. 14, the dealership ... days, it has also been referred to as, “50 for 50.” , Though the ...
(Date:9/17/2019)... ... September 17, 2019 , ... Dr. Jacqueline Subka ... laser dentistry . A minimally invasive approach to gum surgery, laser dentistry is ... Laser dentistry is gentle and effective because it simply uses laser light to ...
(Date:9/17/2019)... ... September 17, 2019 , ... Dr. Perry Patel, ... been certified by the American Academy of Facial Esthetics (AAFE) to administer Botox ... range of orofacial conditions such as tooth clenching and grinding, tongue tension, temporomandibular ...
(Date:9/17/2019)... , ... September 17, 2019 ... ... the October 18 "Pacifica Experience" Open House day on Pacifica's Lambert Campus, ... degree programs in Depth Psychology, the Humanities, Clinical Psychology, Counseling Psychology, and ...
(Date:9/11/2019)... ... September 11, 2019 , ... Workplace injuries cost individuals, ... solve injury risks which lead to musculoskeletal disorders (MSDs). , Starting with ... the team at Soter Analytics helps avoid ergonomic injury by coaching ...
Breaking Medicine News(10 mins):
(Date:9/17/2019)... ... , ... Summer is a time for barbecues, parties and picnics and lots of delicious food ... Douglas Ng, family dentist in San Luis Obispo has some tips for healthy ... popsicles and ice-filled cold drinks to go along with the hot dogs, hamburgers, corn on ...
(Date:9/17/2019)... ... 2019 , ... Dr. Babis Rammos, a renowned plastic surgeon ... Beauty Network, well known for its exclusive and luxurious lifestyle publication Haute Living ... newest addition to the Haute Beauty members-only network. , Haute Beauty offers a ...
(Date:9/14/2019)... ... September 13, 2019 , ... ... in Montreal provided a plethora of breakthrough research studies including several cancer ... to detect breast cancer, response prediction of cancer immunotherapies and whole body, ...
Breaking Medicine Technology:
Cached News: