Animal model demonstrates course of epilepsy

A promising animal model of epilepsy became even more valuable with the demonstration that the course of the disorder closely parallels that of one of the most common forms of epilepsy in humans.

In an article published online June 6, 2005, in the Annals of Neurology, researchers at St. Justine Hospital at the University of Montreal in Canada report that prolonged fever-related seizures in rat pups with underlying brain malformations lead to epilepsy in the rats in adulthood. The article is available via Wiley InterScience at http://www.interscience.wiley.com/journal/ana.

Fever-related, or 'febrile,' seizures are not uncommon in young children and usually have no apparent lasting consequences. However, researchers have noted for a long time that people with temporal lobe epilepsy are more likely to have experienced atypical childhood febrile seizures--ones that occur at lower fever temperatures and last for a long time.

"Our results stress the importance of a careful evaluation of children with atypical febrile seizures. Early identification of children at risk of developing epilepsy could lead to neuroprotective treatments that could prevent the development of later epilepsy," said senior author Lionel Carmant, M.D., of the Sainte-Justine Hospital at the University of Montreal in Canada.

Doctors have long debated whether atypical childhood febrile seizures lead to epilepsy later in life. Researchers have had to consider the alternate possibility that these seizures are merely another manifestation of an underlying disease process that will lead to epilepsy with or without atypical febrile seizures.

The answer to this conundrum has profound treatment implications. Only with a better understanding of the relationship between febrile seizures and adult epilepsy would doctors be able to take aggressive measures to arrest or even prevent the consequences of febrile seiz

Contact: David Greenberg
John Wiley & Sons, Inc.

Page: 1 2

Related medicine news :

1. Animal study leading to new treatments for hemorrhagic shock and uncontrolled abdominal hemorrhage
2. Animal study identifies promising new target for brain tumor therapy
3. Animal BiP levels determine amount of recovery sleep needed following prolonged wakefulness
4. Animal studies suggest vegetables may reduce hardening of arteries
5. Animal models show that anabolic steroids flip the adolescent brains switch for aggression
6. Animal research suggests perimenopause is a critical time for womens health
7. Animal disease reports to be released at July 18 news conference at AVMA convention
8. Animal research suggests new treatment target for epilepsy
9. Test project of patient-centered medical home model endorsed by American College of Physicians
10. Chromatin remodeling complex connected to DNA damage control
11. Mouse model points to possible new strategy for treating rare muscle disease, kidney disorders

Post Your Comments:

(Date:10/13/2017)... ... , ... Global Healthcare Management’s 4th Annual Kids Fun Run brought out many ... event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed at getting kids ... of all ages; it is a non-competitive, non-timed event, which is all about having ...
(Date:10/13/2017)... ... ... “America On The Brink”: the Christian history of the United States and the loss ... author, William Nowers. Captain Nowers and his wife, Millie, have six children, ten ... the Navy. Following his career as a naval aviator and carrier pilot, he ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( https://isocomforter.com ), ... of an innovative new design of the shoulder pad. The shoulder pad provides ... while controlling your pain while using cold therapy. By utilizing ice and water that ...
(Date:10/12/2017)... ... ... HMP , a leader in healthcare events and education, today announced that ... for ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie & Ozzie Awards ... recognizes editorial and design excellence across a range of sectors. This year’s program included ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... $3,296 in property taxes a year. In some states—like New York, New Jersey, ... By contrast, many overseas retirement havens have extremely low property-tax rates, which contributes ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... , Sept. 18, 2017 EpiVax, ... of bioinformatics and immune engineering, today announced ... influenza A (H7N9) vaccine. ... to seasonal influenza and presents a challenge ... prior exposure to be effective. Using state-of-the-art ...
(Date:9/12/2017)... , Sept. 12, 2017   EcoVadis , the leading platform for ... the first annual edition of its Global CSR Risk and Performance Index. ... by EcoVadis, based on Scorecard Ratings that analyzed nearly 800,000 data points ... ... ...
(Date:9/12/2017)... SAN FRANCISCO , Sept. 12, 2017 /PRNewswire/ ... Lifecycle Management Solutions (VLMS), is pleased to announce ... as a member of its Board of Directors ... 2017. ValGenesis VLMS enables life science companies to ... eliminate the use of paper in this process. ...
Breaking Medicine Technology:
Cached News: