Annals of Internal Medicine tip sheet for Oct. 18, 2005

1. Two New Diabetes Treatments May Provide Options for Type 2 Diabetes. Lifestyle Changes Still First Defense

The Oct. 18 issue of Annals of Internal Medicine describes two new diabetes treatments: exenatide, an injected drug; and inhaled insulin. Both treatments have pluses and minuses and were tested on people with type 2 diabetes who were already taking two oral blood-sugar-lowering drugs but whose levels were not under control.

A 26-week trial comparing benefits and harms of exenatide and insulin glargine injections in 551 patients with type 2 diabetes found that both drugs improved overall sugar control, but patients in the exenatide group lost about five pounds, whereas patients in the insulin glargine group gained about four pounds (Article, p. 559).

Patients in the exenatide group had more bad side effects, such as nausea, vomiting and diarrhea, and more patients in this group dropped out of the study than in the insulin glargine group.

Neither drug helped patients achieve recommend fasting sugar levels; only 21.6 percent of the exenatide group and 8.6 percent of the insulin group achieved target blood sugar levels. Also the study participants included only a few African-Americans, a group with a high rate of type 2 diabetes.

A 12-week trial comparing effects of inhaled insulin (a fast-acting insulin) with oral drug therapy in 309 patients, assigned patients to one of three treatments: inhaled insulin alone, inhaled insulin added to two blood-sugar-lowing oral drugs, or oral drug therapy alone (Article, p. 549).

Researchers found that both groups receiving insulin therapy improved blood sugar levels. Patients receiving inhaled insulin gained more weight and had more episodes of hypoglycemia (abnormally low level of blood sugar or glucose) and cough than the oral therapy alone group.

The study didn't compare inhaled insulin with injected insulin and only lasted 12 weeks, so the drug's long-ter

Contact: Susan Anderson
American College of Physicians

Page: 1 2

Related medicine news :

1. Annals of Internal Medicine tip sheet for Aug. 7, 2007, issue
2. May/June Annals of Family Medicine tip sheet
3. Annals of Internal Medicine Tip Sheet for May 15, 2007
4. Tip sheet for Annals of Internal Medicine -- May 1, 2007, issue
5. Tip sheet Annals of Internal Medicine, April 17, 2007
6. Embargoed March/April Annals of Family Medicine tip sheet
7. Annals of Internal Medicine tip sheet for March 6, 2007
8. Annals of Internal Medicine tip sheet for Feb. 20, 2007, issue
9. Embargoed Jan./Feb. Annals of Family Medicine tip sheet
10. November/December 2006 Annals of Family Medicine tip sheet
11. Annals of Internal Medicine tip sheet for December 5, 2006

Post Your Comments:

(Date:10/13/2017)... ... 2017 , ... As health professionals work to improve their approach to healthcare, ... doing more than filling out a survey; in many cases health professionals and patients ... health care and research on the importance of active engagement with patients and members ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... ‘17, and Jennifer Huggins, PharmD ’17, along with clinical associate professor Janice ... of cardiovascular diseases during the 15th Annual Women’s Health Conference. The SIU ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for professional women, ... towards gender equality at their inaugural Summit in New York City in June. The ... social audience of over 3 million. To watch the Mobilize Women video, click ...
(Date:10/13/2017)... ... ... Journey: From the Mountains to the Mission Field”: the story of a missionary couple ... From the Mountains to the Mission Field” is the creation of published author, Carole ... and currently teaches a class of ladies at her church, which she has taught ...
(Date:10/12/2017)... WAUSAU, Wis. (PRWEB) , ... October 12, 2017 ... ... formulated standard products to meet the demand of today’s consumer and regulatory authorities ... team of probiotic experts and tested to meet the highest standard. , ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... -- West Pharmaceutical Services, Inc. (NYSE: WST), ... administration, today announced that it will release third-quarter 2017 ... 26, 2017, and will follow with a conference call ... a.m. Eastern Time. To participate on the call, please ... is 94093362. A ...
(Date:10/11/2017)... CHICAGO , Oct. 11, 2017  Hill-Rom Holdings, ... its Aspen Surgical facility in Las Piedras, ... surgical scalpels and blades. ... confirmed that the facility sustained minor structural damage, temporary ... Hurricane Maria. Repairs have been completed, manufacturing operations have ...
(Date:10/5/2017)...  In response to the nationwide opioid epidemic, ... (AAOMS) released prescribing recommendations that urge ibuprofen – ... a first-line therapy to manage a patient,s acute ... Recognizing the value and importance of the ... Acute and Postoperative Pain Management" stresses that practitioners ...
Breaking Medicine Technology:
Cached News: