Annals of Internal Medicine tip sheet for Oct. 18, 2005

1. Two New Diabetes Treatments May Provide Options for Type 2 Diabetes. Lifestyle Changes Still First Defense

The Oct. 18 issue of Annals of Internal Medicine describes two new diabetes treatments: exenatide, an injected drug; and inhaled insulin. Both treatments have pluses and minuses and were tested on people with type 2 diabetes who were already taking two oral blood-sugar-lowering drugs but whose levels were not under control.

A 26-week trial comparing benefits and harms of exenatide and insulin glargine injections in 551 patients with type 2 diabetes found that both drugs improved overall sugar control, but patients in the exenatide group lost about five pounds, whereas patients in the insulin glargine group gained about four pounds (Article, p. 559).

Patients in the exenatide group had more bad side effects, such as nausea, vomiting and diarrhea, and more patients in this group dropped out of the study than in the insulin glargine group.

Neither drug helped patients achieve recommend fasting sugar levels; only 21.6 percent of the exenatide group and 8.6 percent of the insulin group achieved target blood sugar levels. Also the study participants included only a few African-Americans, a group with a high rate of type 2 diabetes.

A 12-week trial comparing effects of inhaled insulin (a fast-acting insulin) with oral drug therapy in 309 patients, assigned patients to one of three treatments: inhaled insulin alone, inhaled insulin added to two blood-sugar-lowing oral drugs, or oral drug therapy alone (Article, p. 549).

Researchers found that both groups receiving insulin therapy improved blood sugar levels. Patients receiving inhaled insulin gained more weight and had more episodes of hypoglycemia (abnormally low level of blood sugar or glucose) and cough than the oral therapy alone group.

The study didn't compare inhaled insulin with injected insulin and only lasted 12 weeks, so the drug's long-ter

Contact: Susan Anderson
American College of Physicians

Page: 1 2

Related medicine news :

1. Annals of Internal Medicine tip sheet for Aug. 7, 2007, issue
2. May/June Annals of Family Medicine tip sheet
3. Annals of Internal Medicine Tip Sheet for May 15, 2007
4. Tip sheet for Annals of Internal Medicine -- May 1, 2007, issue
5. Tip sheet Annals of Internal Medicine, April 17, 2007
6. Embargoed March/April Annals of Family Medicine tip sheet
7. Annals of Internal Medicine tip sheet for March 6, 2007
8. Annals of Internal Medicine tip sheet for Feb. 20, 2007, issue
9. Embargoed Jan./Feb. Annals of Family Medicine tip sheet
10. November/December 2006 Annals of Family Medicine tip sheet
11. Annals of Internal Medicine tip sheet for December 5, 2006

Post Your Comments:

(Date:10/13/2017)... ... October 13, 2017 , ... Global Healthcare Management’s 4th Annual Kids Fun Run ... This free event, sponsored by Global Healthcare Management’s CEO, Jon Letko, is aimed ... geared towards children of all ages; it is a non-competitive, non-timed event, which is ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: ... “America On The Brink” is the creation of published author, William Nowers. ... As a WWII veteran, he spent thirty years in the Navy. Following ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( ... today the introduction of an innovative new design of the shoulder pad. The ... get maximum comfort while controlling your pain while using cold therapy. By utilizing ice ...
(Date:10/12/2017)... ... , ... HMP , a leader in healthcare events and education, today announced ... Award for ‘Best B-to-B Healthcare Website.’ Winners were announced during the Eddie & Ozzie ... competition recognizes editorial and design excellence across a range of sectors. This year’s program ...
(Date:10/12/2017)... ... 12, 2017 , ... In the United States, single-family home ... states—like New York, New Jersey, Massachusetts, Texas, Virginia, Connecticut, and California—the average is ... low property-tax rates, which contributes to the relatively lower cost of living in ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... --  Divoti USA will engrave and process all ... the latest FDA requirements, which stipulates new criteria regarding medical device ... of Medical ID jewelry such as Medical ID Bracelets, can rest ... terms of the new FDA requirements . ... Divoti offers this dark mark fiber laser engraving ...
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ... on fulfilling the promise of precision medicine, today announced ... joined Caris, Precision Oncology Alliance™ (POA) as its 17 ... centers, the St. Jude Crosson Cancer Institute will help ... the use of tumor profiling, making cancer treatment more ...
(Date:10/10/2017)... ORANGE COUNTY, Calif. , Oct. 10, 2017  NDS received ... Mobile  — a medical-grade battery-powered display stand specifically designed for ... aims to transform technology into a clinical solution to support the ... costs. Innovative Design ... NDS ZeroWire Mobile Wireless Solution ...
Breaking Medicine Technology:
Cached News: