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Anti-malarials most effective in lupus patients genetically at risk of high levels of TNF-alpha

rial drugs. For patients who do not have the polymorphisms, the difference in TNF-alpha levels was much less significant between patients who were on anti-malarial therapy and patients who were not. Patients with both polymorphisms had a four times higher probability to respond well to anti-malarial therapy (and not need any other therapy) than other patients.


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BioMed Central
12-Feb-2006


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