HOME >> MEDICINE >> NEWS
Antidepressant use during pregnancy appears associated with withdrawal symptoms in newborns

Almost one-third of 60 newborn infants whose mothers took antidepressants during pregnancy experienced neonatal abstinence syndrome, a type of withdrawal with symptoms that include high-pitched crying, tremors and disturbed sleep, according to a study in the February issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

Between one-tenth and one-fourth of women will develop depression in their lifetimes, according to background information in the article. The stress of pregnancy can worsen the condition and increase the need for medications. Selective serotonin reuptake inhibitors (SSRIs) are a commonly used class of antidepressants; they are known to cross the placenta, prompting research into their effects on infants.

Rachel Levinson-Castiel, M.D., of the Children's Medical Center of Israel, Petah Tiqwa, and colleagues examined 120 babies born between Jan. 1, 2002, and Aug. 31, 2004, at Rabin Medical Center in Israel. Sixty of the infants' mothers took SSRIs for prolonged periods of time, including during the third trimester. These infants and 60 control infants without exposure to SSRIs were assessed two hours after birth and again at regular intervals if they displayed withdrawal symptoms.

Of the 60 infants with exposure to SSRIs, 18 (30 percent) had neonatal abstinence syndrome and eight of those cases were severe. The most common symptoms were tremor, gastrointestinal problems, an abnormal increase in muscle tone (hypertonicity), sleep disturbances and high-pitched cries. None of the infants with symptoms required treatment, and none of the 60 infants without exposure to SSRIs developed the syndrome.

"The high prevalence of neonatal abstinence syndrome in infants exposed to SSRIs in utero should be brought to the attention of family physicians, psychiatrists, gynecologists, pediatricians and mothers," the authors write. "Because maternal depression during pregnancy also entails a risk to
'"/>

Contact: Gil Klinger, M.D.
gilkl@post.tau.ac.il
JAMA and Archives Journals
6-Feb-2006


Page: 1 2

Related medicine news :

1. Antidepressant does not improve symptoms in advanced cancer patients without major depression
2. Antidepressants safe for children and adolescents
3. Antidepressants improve post-stroke thinking outside the box
4. CIHR-funded research: Antidepressants help men decrease alcohol consumption, but not women
5. Antidepressants associated with increased risk for suicide attempts, decreased risk for death
6. Antidepressant drug may prevent recurrence of depression in patients with diabetes
7. Antidepressant medication may prevent recurring depression in diabetics
8. Antidepressants might reduce risk of colorectal cancer
9. Antidepressants may be associated with modestly increased risk of suicidality in children
10. Antidepressant therapy for major depression in children and adolescents
11. Antidepressants and electroconvulsive therapy are the best treatment options for depression

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/11/2019)... ... ... Early praise for A Nurse’s Step-by-Step Guide to Publishing a Dissertation or ... key insight and vital guidance for publishing dissertations or DNP projects. A Nurse’s Step-by-Step ... my bookshelf and will be shared with new graduates and colleagues alike.” , ...
(Date:11/11/2019)... ... 11, 2019 , ... Smile Brands Inc., one of the ... States, today announced the grand opening of another affiliated Bright Now! Dental ... hours, comfortable offices and full-service care at the new location. The newest Bright ...
(Date:11/11/2019)... ... November 11, 2019 , ... Last year’s expo was ... countries including big box buyers like Costco, Walmart, and GNC. Exhibitors included some ... name a few. , This year, CBD.io and partners, are once ...
(Date:11/11/2019)... ... November 11, 2019 , ... ... for improved foodborne illness prevention and urges increased adoption of compliance technology in ... series of vegetable products sold to select retailers in the United States and ...
(Date:11/11/2019)... ... November 11, 2019 , ... PracticeLink Live! Atlanta Physician Career Fair will ... begin at 5:00 p.m. and continue until 8:00 p.m. A free, optional seminar for ... begin at 6:30 p.m. , Both the career fair and seminar are open to ...
Breaking Medicine News(10 mins):
(Date:11/12/2019)... (PRWEB) , ... November 12, 2019 , ... ... opening of a new medication-assisted treatment (MAT) facility in the Cincinnati, OH suburb ... including medication, counseling and support services. The clinic, located at 749C State Route ...
(Date:11/11/2019)... CHARLOTTE, N.C., and GREENSBORO, N.C. (PRWEB) , ... November 11, 2019 ... ... that delivers value-based care to adults on Medicare, has opened two new centers in ... healthcare as it should be, Oak Street Health offers an entirely different model of ...
(Date:11/11/2019)... ... November 11, 2019 , ... ... facilitate the coordination and implementation of joint projects for the benefit of ... undertakings will empower biomedical professionals to leverage their roles in the research, ...
Breaking Medicine Technology:
Cached News: