Antidepressants improve post-stroke 'thinking outside the box'

Antidepressant treatment appears to help stroke survivors with the kind of complex mental abilities often referred to as "thinking outside the box," according to a University of Iowa study.

The antidepressants' effects on study participants' abilities were independent of any changes in depression. In addition, the improvements in complex mental abilities were not seen immediately but during the course of 21 months after the treatment ended. The study results appear in the March 2007 issue of the British Journal of Psychiatry.

Antidepressant treatment already was known to improve mood in depressed post-stroke patients, but such therapy had not been examined on executive function in people with clinically diagnosed stroke, said Sergio Paradiso, M.D., Ph.D., the study's corresponding author and assistant professor of psychiatry at the UI Carver College of Medicine.

"We found that people diagnosed with stroke who often have a decline in 'executive function', that is, those mental abilities that enable us to respond appropriately to unfamiliar or complex situations, and support several cognitive, emotional and social capacities, showed improvement after receiving a 12-week treatment with antidepressants," Paradiso said.

Executive functions come into play, for instance, when we plan to take an alternative route home due to unexpected detours. This brain function involves stopping ingrained behavior, such as trying to take your usual route home. People with stroke often show impairments in executive function and may not be able to respond well to non-routine situations. This impairment may affect rehabilitation efforts.

The UI team included Kenji Narushima, M.D, Ph.D., UI resident physician in psychiatry, who contributed significantly to the study.

The study began with 47 patients who had had a stroke during the previous six months. These individuals were divided into three groups and randomly assigned (with

Contact: Becky Soglin
University of Iowa

Page: 1 2 3

Related medicine news :

1. Antidepressants safe for children and adolescents
2. CIHR-funded research: Antidepressants help men decrease alcohol consumption, but not women
3. Antidepressants associated with increased risk for suicide attempts, decreased risk for death
4. Antidepressants might reduce risk of colorectal cancer
5. Antidepressants may be associated with modestly increased risk of suicidality in children
6. Antidepressants and electroconvulsive therapy are the best treatment options for depression
7. Antidepressants should be first-line approach for nerve tissue pain
8. Antidepressants may lower risk of recurrent heart attack in depressed heart attack patients
9. Antidepressants lessen risk of heart attack, Stanford researcher says
10. Early-childhood intervention may improve well-being through young adulthood
11. U of M report says early-childhood intervention improves well-being through young adulthood

Post Your Comments:

(Date:10/13/2015)... ... October 13, 2015 , ... According to an article ... has shown that women who successfully lose weight with a bariatric procedure are much ... each year. The article notes that anywhere from 40 to 50 percent of all ...
(Date:10/13/2015)... ... , ... Symposium Chairman, Dr. Rod J. Rohrich is pleased to announce that ... March 2nd and 3rd, 2016. The annual meeting, along with the Dallas Rhinoplasty ... around the world. , Key topics at this year's event will include discussions on ...
(Date:10/13/2015)... ... October 13, 2015 , ... Relay (relaynetwork.com), ... application, announced today a significant contract that will provide its award-winning private messaging ... build on the growing success of its Relay program, IBX Wire™, which now ...
(Date:10/13/2015)... ... October 13, 2015 , ... NavaFit Inc. today announced the launch of its ... with, participate in local fitness & sporting events, and stay motivated. Users ... medical costs drive us to get more serious about fitness and wellness, individuals are ...
(Date:10/13/2015)... ... 13, 2015 , ... Protein is essential to good health. You need it ... But how much protein does the average man need in order to stay healthy? ... October 2015 issue of Harvard Men's Health Watch . Most Americans get about ...
Breaking Medicine News(10 mins):
(Date:10/13/2015)... , Oct. 13, 2015  XiMo AG ( ... Aspira Scientific, Inc. ( Milpitas, California ) ... for metathesis chemistry. The importance of metathesis chemistry was ... the pioneers of this application. This industrially-relevant application has ... such as pharmaceuticals, specialty chemicals, and polymers. ...
(Date:10/12/2015)... LONDON , Oct. 12, 2015 ... performance, the setbacks and the needs of the medical ... strategies of membrane devices within the different medical membrane ... filters, blood microfilters/apheresis systems and membrane diagnostic devices. - ... alerts in this market. --> Use this ...
(Date:10/12/2015)... 12, 2015 Zimmer Biomet Holdings, Inc. (NYSE ... sales and earnings conference call will be broadcast live ... 8 a.m. Eastern Time.  A news release detailing the ... Eastern Time the morning of the conference call. ... following the conference call. --> http://investor.zimmerbiomet.com .  ...
Breaking Medicine Technology:
Cached News: