HOME >> MEDICINE >> NEWS
Antidepressants might reduce risk of colorectal cancer

Use of some antidepressants might reduce the risk of developing colorectal cancer, according to researchers reporting in the April issue of The Lancet Oncology. The antidepressants known as selective serotonin reuptake inhibitors (SSRI) "might inhibit the growth of colorectal tumours", says lead investigator Prof Jean-Paul Collet (Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada).

Results from studies of antidepressant use and cancer risk have been inconsistent and focused mainly on cancers of the breast and ovaries. The risk associated with colorectal cancers is unknown. In the USA, about 100 million prescriptions of antidepressants are written every year and SSRI are the most commonly used. Animal studies have suggested that SSRI reduce the growth of colorectal tumours. Therefore, researchers postulated that these drugs might reduce the risk of colorectal cancer in humans.

In the study, researchers identified 3367 cases with colorectal cancer and matched them for age, sex, and calendar time with controls without cancer. After adjustment for non-steroidal antiflammatory use during the same period and SSRI use 6-10 years before diagnosis, they found a decreased risk of cancer for those taking a high (>6.0x10-6 mol per day) SSRI dose 0-5 years before diagnosis.

Prof Collet states: "Further investigation is needed, with more complete assessment of confounders such as lifestyle factors, use of drugs, and comorbidity that might affect the occurence of colorectal cancer".

In an accompanying Reflection and Reaction, Prof Henrik Toft Srensen (Aarhus University Hospital, Aarhus, Denmark) comments that data from the study "provide interesting insights, but until trial data is available, clinicians should not consider SSRI use solely for chemopreventive purposes".


'"/>

Contact: Joe Santangelo
j.santangelo@elsevier.com
212-633-3810
Lancet
26-Mar-2006


Page: 1

Related medicine news :

1. Antidepressants safe for children and adolescents
2. Antidepressants improve post-stroke thinking outside the box
3. CIHR-funded research: Antidepressants help men decrease alcohol consumption, but not women
4. Antidepressants associated with increased risk for suicide attempts, decreased risk for death
5. Antidepressants may be associated with modestly increased risk of suicidality in children
6. Antidepressants and electroconvulsive therapy are the best treatment options for depression
7. Antidepressants should be first-line approach for nerve tissue pain
8. Antidepressants may lower risk of recurrent heart attack in depressed heart attack patients
9. Antidepressants lessen risk of heart attack, Stanford researcher says
10. Snoring in children might be an allergic type disease
11. New imaging compound might see Alzheimers earlier

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... ... 03, 2020 , ... MemoryCare.com, a comprehensive resource for caregivers ... Facilities in Louisville, KY. The guide identifies 17 memory care communities based on ... Alzheimer’s Association , 5.6 million people age 65 and older are living ...
(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... ... it has completed $3 million convertible note financing, which will be used to ... With the funds from this financing, the company will continue to expand its ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... are joining biomedical engineers from Carnegie Mellon University (CMU) to develop a new ... who have undergone open heart surgery. , The AGH/CMU team was recently awarded ...
(Date:8/31/2020)... ... 31, 2020 , ... Want to get moving, break up your routine, and ... is thrilled to launch its fourth annual STEPtember campaign in the United States to ... everyone wherever they are at this moment — encouraging people to move in the ...
(Date:8/31/2020)... ... August 31, 2020 , ... The pandemic and topsy-turvy economic outlook continues to put financial ... look for ways to trim the fat from our monthly expenses and put more into ... also important that you have a financial safety net in place in case something were ...
Breaking Medicine News(10 mins):
(Date:8/28/2020)... ... August 28, 2020 , ... Dr. Mark Surrey has ... surgeon and serves as a clinical professor in the Department of OBGYN at UCLA’s ... Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical Director of Fellowship ...
(Date:8/27/2020)... ... August 27, 2020 , ... The flu season is right round the corner and the ... with all the necessary measures before it begins to harbor its effects on us. Already ... is leaving a huge impact on our lives. Hence it has become even more relevant ...
(Date:8/27/2020)... ... , ... The GHT Companies , a leading developer and distributor of ... Diego with a press conference at its manufacturing facility in Vista. Here ... representing an overall donation result exceeding $30,000 to Feeding San Diego, Who: Jim ...
Breaking Medicine Technology:
Cached News: