HOME >> MEDICINE >> NEWS
Antidepressants safe for children and adolescents

OCD and anxiety in children and adolescents under the age of 19. Fifteen trials were of major depressive disorder and included a total of 3,430 participants; six trials were of OCD, with 718 participants; and six trials were of anxiety, with 1,162 participants. The drugs used were the selective serotonin reuptake inhibitors (SSRIs) nefazodone, venlafaxine and mirtazapine; all of the studies were randomized and placebo-controlled.

Researchers found that one in 100 participants in the studies included in the meta-analysis had new-onset suicidal ideation, or suicidal thoughts, while on medication. Even fewer acted on these thoughts, and there were no completed suicides.

The results showed that antidepressants were most effective in treating anxiety, moderately effective for OCD and modestly effective for depression. The number needed to treat (NNT) a statistical term meaning the number of patients a clinician would need to treat to prevent an adverse outcome in one was 10 for major depressive disorder, six for OCD and four for anxiety. The number needed to harm (NNH) the number of patients who would need to be treated for one to be harmed was 112 for major depressive disorder, 200 for OCD and 143 for anxiety. These numbers indicate that the increased risk, while not unimportant, is not enough to outweigh the benefits of taking the medications.

"While I support the FDAs role in monitoring the safety of medications, in this case, the FDA should reconsider the black box warning on these medications," said Dr. Brent. "Our study supports the cautious and well-monitored use of antidepressant medications as a first-line treatment for anxiety, OCD and depression."


'"/>

Contact: Jocelyn Uhl Duffy
UhlJH@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
17-Apr-2007


Page: 1 2

Related medicine news :

1. Antidepressants improve post-stroke thinking outside the box
2. CIHR-funded research: Antidepressants help men decrease alcohol consumption, but not women
3. Antidepressants associated with increased risk for suicide attempts, decreased risk for death
4. Antidepressants might reduce risk of colorectal cancer
5. Antidepressants may be associated with modestly increased risk of suicidality in children
6. Antidepressants and electroconvulsive therapy are the best treatment options for depression
7. Antidepressants should be first-line approach for nerve tissue pain
8. Antidepressants may lower risk of recurrent heart attack in depressed heart attack patients
9. Antidepressants lessen risk of heart attack, Stanford researcher says
10. Chinese children with hearing devices benefit from new speech test
11. Seat belt injuries could signal more serious trauma in children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/16/2018)... ... November 16, 2018 , ... ... offer treatment options to patients suffering from chronic pelvic pain. In addition ... treatment of various pelvic pain disorders including endometriosis, menorrhagia (abnormal heavy bleeding ...
(Date:11/16/2018)... ... ... The Colorado Rural Health Center (CRHC) is proud to recognize the innovation, quality ... Rural Health Day 2018. National Rural Health Day falls on the third Thursday in ... over 60 million people across the nation. , This year, CRHC is celebrating ...
(Date:11/16/2018)... OVIEDO, Fla. (PRWEB) , ... November 16, 2018 , ... ... a benefit matching skin care product called Lipo-6 Defining Gel . Utilizing TopiSorbTM ... organ, the skin. Stubborn cellulite and fatty deposits have met their match. , ...
(Date:11/16/2018)... ... November 16, 2018 , ... ... Framework (RMF) approved, cloud-based Force Protection and Emergency Management solutions who announced today ... contract to provide these services Army-wide. , Under the contract, E-9 will expand ...
(Date:11/16/2018)... SEATTLE (PRWEB) , ... November 16, 2018 , ... ... of their Best Online Master's in Educational Psychology Programs for 2019. They have ... areas of curriculum quality, program flexibility, affordability, and graduate outcomes. , Leveraging an ...
Breaking Medicine News(10 mins):
(Date:11/15/2018)... BOCA RATON, Fla. (PRWEB) , ... November 15, ... ... it has begun accepting CBD merchant account applications in the U.S. and Canadian ... card present setting. This change comes after a thorough review and understanding of ...
(Date:11/15/2018)... ... 15, 2018 , ... Catalent Pharma Solutions, the leading global ... health products, today announced that Pete Young, Director of Quality at Catalent’s Bolton, ... (PCT) conference at the CCIB Convention Centre Barcelona, Barcelona, Spain on Nov. 27 ...
(Date:11/15/2018)... ... 15, 2018 , ... Registration is now open for the ... case management conference enriching the entire healthcare continuum. The conference is scheduled for ... professionals will convene to elevate their careers and experience an event designed for ...
Breaking Medicine Technology:
Cached News: