HOME >> MEDICINE >> NEWS
Antidepressants safe for children and adolescents

OCD and anxiety in children and adolescents under the age of 19. Fifteen trials were of major depressive disorder and included a total of 3,430 participants; six trials were of OCD, with 718 participants; and six trials were of anxiety, with 1,162 participants. The drugs used were the selective serotonin reuptake inhibitors (SSRIs) nefazodone, venlafaxine and mirtazapine; all of the studies were randomized and placebo-controlled.

Researchers found that one in 100 participants in the studies included in the meta-analysis had new-onset suicidal ideation, or suicidal thoughts, while on medication. Even fewer acted on these thoughts, and there were no completed suicides.

The results showed that antidepressants were most effective in treating anxiety, moderately effective for OCD and modestly effective for depression. The number needed to treat (NNT) a statistical term meaning the number of patients a clinician would need to treat to prevent an adverse outcome in one was 10 for major depressive disorder, six for OCD and four for anxiety. The number needed to harm (NNH) the number of patients who would need to be treated for one to be harmed was 112 for major depressive disorder, 200 for OCD and 143 for anxiety. These numbers indicate that the increased risk, while not unimportant, is not enough to outweigh the benefits of taking the medications.

"While I support the FDAs role in monitoring the safety of medications, in this case, the FDA should reconsider the black box warning on these medications," said Dr. Brent. "Our study supports the cautious and well-monitored use of antidepressant medications as a first-line treatment for anxiety, OCD and depression."


'"/>

Contact: Jocelyn Uhl Duffy
UhlJH@upmc.edu
412-647-3555
University of Pittsburgh Schools of the Health Sciences
17-Apr-2007


Page: 1 2

Related medicine news :

1. Antidepressants improve post-stroke thinking outside the box
2. CIHR-funded research: Antidepressants help men decrease alcohol consumption, but not women
3. Antidepressants associated with increased risk for suicide attempts, decreased risk for death
4. Antidepressants might reduce risk of colorectal cancer
5. Antidepressants may be associated with modestly increased risk of suicidality in children
6. Antidepressants and electroconvulsive therapy are the best treatment options for depression
7. Antidepressants should be first-line approach for nerve tissue pain
8. Antidepressants may lower risk of recurrent heart attack in depressed heart attack patients
9. Antidepressants lessen risk of heart attack, Stanford researcher says
10. Chinese children with hearing devices benefit from new speech test
11. Seat belt injuries could signal more serious trauma in children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... ... October 13, 2017 , ... Lori R. Somekh, founder of the ... national organization of elder law and special needs planning attorneys. “Membership in ElderCounsel helps ... provides a forum to network with elder law attorneys nationwide,” said Somekh. , ...
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... York, NY (PRWEB) , ... October 13, 2017 , ... ... influential people in business to advocate for action towards gender equality at their inaugural ... views from around the globe, and reached a social audience of over 3 million. ...
(Date:10/13/2017)... ... 13, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House of ... popular and least understood books in the Holy Scriptures, Revelation. The Book of Revelation ... scholars for centuries. Many have tossed it off as mere rubbish, but Yisrayl Hawkins ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Software Development, has been awarded a contract by the Center for Medicare and ... aims to accelerate the enterprise use of Agile methodologies in a consistent and ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... received FDA 510(k) clearance in May 2017 for its highly anticipated ... for endoscopy environments. An innovative secondary monitor solution, ZeroWire Mobile ... the improvement of patient outcomes, procedural efficiency, and the lowering of ... ... By ...
(Date:10/7/2017)... 6, 2017   Provista, a proven leader ... billion in purchasing power, today announced a new resource ... The Newsroom is the online home for case ... expert bios, news releases, slideshows and events. ... wealth of resources at their fingertips, viewers can also ...
(Date:10/4/2017)... , Oct. 4, 2017  South Korean-based healthcare product ... training aide "cprCUBE" on Kickstarter. The device will educate ... cardiac arrests with better efficiency compared to the dated ... real-time feedback on efficacy of the compression for a ... has a goal to raise $5,000. ...
Breaking Medicine Technology:
Cached News: