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Anxious and pessimistic personalities linked to Parkinson's disease later in life

ase later in life. Previous work done at Mayo Clinic and at other medical centers had given Dr. Bower's team hints that there might be psychiatric conditions or personality types that might put some people at increased risk for Parkinson's disease.

From an initial group of 7,216 people who took the Minnesota Multiphasic Personality Inventory (MMPI) between 1962 and 1965, the investigators were able to find information on 4,741 of them; 128 had developed Parkinson's disease. The researchers then looked at the MMPI scales for the categories of depression, anxiety, social introversion and pessimism. They found that those who had scored in the top 25 percent in the anxiety and pessimism scales were more likely to have developed Parkinson's disease than those in the bottom 75 percent.

Parkinson's disease is a disorder that affects nerve cells (neurons) in the part of the brain controlling muscle movement. People with Parkinson's often experience trembling, muscle rigidity, difficulty walking, and problems with balance and coordination. These symptoms generally develop after age 50, although the disease affects a small percentage of younger people as well.


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Contact: Lisa Lucier
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
13-Apr-2005


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