HOME >> MEDICINE >> NEWS
Are higher doses of cholesterol drugs worth the extra money? Only sometimes, study says

ANN ARBOR, Mich. -- When it comes to cholesterol-lowering drugs, more is better. At least, thats what heart doctors and heart patients have been hearing in recent years. And as a result, more patients are taking higher doses of drugs called statins leading to lower heart and stroke risk, but higher prescription drug costs and more frequent side effects.

Now, a new study looks at whether those higher doses, and higher costs, are really going to pay off for some patients. For those with a recent heart attack or what doctors call acute coronary syndrome, the answer is yes, the researchers say.

But the picture is less clear for those patients with known heart blockages who have stable symptoms. For them, the usual dose of their statin may provide adequate heart-protecting benefit, and the higher cost of high-dose statins may provide only marginal benefit at much greater cost, especially if they use generic statins.

The study, from a team at the University of Michigan Cardiovascular Center and the VA Ann Arbor Healthcare System, is published online in the journal Circulation, and will be in the May 8 print issue of the journal. Its based on a sophisticated computer analysis of data from thousands of patients.

The team finds that patients with a recent history of acute coronary syndrome (ACS) either a heart attack or hospital stay for chest pain get so much benefit from higher doses of statins (over four additional quality-adjusted months of life) that the extra cost of the increased dose is worthwhile, even if the difference is a few dollars a day.

But for patients with stable coronary artery disease (CAD), whose arteries have been narrowed by plaque but who havent had a recent heart attack or hospitalization for chest pain, the much smaller gain (about 5 weeks of quality-adjusted life) from a higher dose of a statin may not be sufficient to outweigh the extra cost.

The researchers also point out that
'"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
23-Apr-2007


Page: 1 2 3 4 5

Related medicine news :

1. Women with migraines and visual symptoms may have higher stroke risk
2. Study explains why patients with OSA are at higher risk for cardiovascular disease
3. Tiny newborns face higher risk of death at community hospitals, Stanford/VA study finds
4. Persistent smokers may have higher risk to become depressed than never smokers
5. Veterans exposed to Agent Orange have higher rates of prostate cancer recurrence
6. Exposure to mercury preservatives before birth is no higher in children with autism
7. Post-traumatic stress disorder 10 times higher in New Orleans than in the general public
8. Uveal melanoma patients at higher risk for colon cancer
9. Girls born with HIV infection at higher risk for cervical problems
10. Detection of melanoma by dermatologists linked with earlier tumor stage, higher survival rates
11. Adoption of health information technology will lead to higher standard of quality care

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... ... August 31, 2020 , ... Ocean ... face masks to medical first responders across the United States. Since the start ... personal protective equipment (PPE) medical centers , hospitals , firefighters ...
(Date:8/31/2020)... , ... August 31, 2020 , ... ... business management solution for chiropractors, announced today the launch of its integrated, HIPAA ... can start running their virtual practice in under 90 seconds. , According ...
(Date:8/31/2020)... ... August 31, 2020 , ... Smile Brands Inc., one ... the United States, today announced the grand opening of another affiliated Bright ... will enjoy convenient hours, a comfortable office, and full-service care at the new ...
(Date:8/31/2020)... ... ... “PTS” with Mediation & Hypnosis , At this very turbulent time in the world, ... immense stress, and right now are needing serious relief from a constant state of endless ... experiencing a great degree of emotional discomfort, be it fear or worrying about their income ...
(Date:8/31/2020)... PASADENA, Calif. (PRWEB) , ... August 31, 2020 ... ... and leadership experience working, both directly with persons with autism and other developmental ... clinical expertise includes early intervention, parent education, adolescents with autism, school consultation, and ...
Breaking Medicine News(10 mins):
(Date:9/2/2020)... ... September 02, 2020 , ... ... technology, will moderate a roundtable discussion among industry professionals about successes and challenges ... hosted by American Pharmaceutical Review and will take place on October ...
(Date:9/1/2020)... ... September 01, 2020 , ... ... host the Agilent Science and Technology Virtual Symposium 2020 (ASTVS 2020) ... will open a suite of Live webinars and Networking sessions, with a vast ...
(Date:9/1/2020)... (PRWEB) , ... September 01, 2020 , ... While coronavirus ... alarming rate as businesses, schools and community organizations remain closed. Because about 80% of ... needs the help of both blood donors and blood drive hosts to ensure blood ...
Breaking Medicine Technology:
Cached News: