HOME >> MEDICINE >> NEWS
Are higher doses of cholesterol drugs worth the extra money? Only sometimes, study says

ANN ARBOR, Mich. -- When it comes to cholesterol-lowering drugs, more is better. At least, thats what heart doctors and heart patients have been hearing in recent years. And as a result, more patients are taking higher doses of drugs called statins leading to lower heart and stroke risk, but higher prescription drug costs and more frequent side effects.

Now, a new study looks at whether those higher doses, and higher costs, are really going to pay off for some patients. For those with a recent heart attack or what doctors call acute coronary syndrome, the answer is yes, the researchers say.

But the picture is less clear for those patients with known heart blockages who have stable symptoms. For them, the usual dose of their statin may provide adequate heart-protecting benefit, and the higher cost of high-dose statins may provide only marginal benefit at much greater cost, especially if they use generic statins.

The study, from a team at the University of Michigan Cardiovascular Center and the VA Ann Arbor Healthcare System, is published online in the journal Circulation, and will be in the May 8 print issue of the journal. Its based on a sophisticated computer analysis of data from thousands of patients.

The team finds that patients with a recent history of acute coronary syndrome (ACS) either a heart attack or hospital stay for chest pain get so much benefit from higher doses of statins (over four additional quality-adjusted months of life) that the extra cost of the increased dose is worthwhile, even if the difference is a few dollars a day.

But for patients with stable coronary artery disease (CAD), whose arteries have been narrowed by plaque but who havent had a recent heart attack or hospitalization for chest pain, the much smaller gain (about 5 weeks of quality-adjusted life) from a higher dose of a statin may not be sufficient to outweigh the extra cost.

The researchers also point out that
'"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
23-Apr-2007


Page: 1 2 3 4 5

Related medicine news :

1. Women with migraines and visual symptoms may have higher stroke risk
2. Study explains why patients with OSA are at higher risk for cardiovascular disease
3. Tiny newborns face higher risk of death at community hospitals, Stanford/VA study finds
4. Persistent smokers may have higher risk to become depressed than never smokers
5. Veterans exposed to Agent Orange have higher rates of prostate cancer recurrence
6. Exposure to mercury preservatives before birth is no higher in children with autism
7. Post-traumatic stress disorder 10 times higher in New Orleans than in the general public
8. Uveal melanoma patients at higher risk for colon cancer
9. Girls born with HIV infection at higher risk for cervical problems
10. Detection of melanoma by dermatologists linked with earlier tumor stage, higher survival rates
11. Adoption of health information technology will lead to higher standard of quality care

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/13/2016)... Springs, FL (PRWEB) , ... February 13, 2016 , ... ... the environmental impact of American businesses. , The increasingly modern world of instantaneous ... more often on non-renewable energy sources such as oil and coal, which pollutes our ...
(Date:2/13/2016)... ... February 13, 2016 , ... In the early or “honeymoon” stage of a ... go out of their way to be romantic, and may exaggerate a strength or ... any online dating profile. , A recent study from Queendom.com , however, ...
(Date:2/12/2016)... ... February 12, 2016 , ... The law firm of Morrow, Morrow, ... The purpose of these scholarships is to encourage applicants to pursue a degree ... employment within these two parishes. , “We have available jobs in St. Landry ...
(Date:2/12/2016)... ... February 12, 2016 , ... Fixed ... p.m. – 3:00 p.m. EST, http://www.fdanews.com/fixeddosecombination , Fixed ... pharmaceutical products, garnering increased attention from all stakeholders in the development of new ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... nominations have closed for the ISE Southeast Awards 2016. Finalists and winners of ... the ISE® Southeast Executive Forum and Awards Gala on March 15, 2016 at ...
Breaking Medicine News(10 mins):
(Date:2/11/2016)... 11, 2016 Laboratory glassware and ... laboratories. These may range from microscope slides to large ... made from borosilicate glass because of its low weight ... other hand, started gaining popularity over the past decade ... replace glass with plastic in several applications due to ...
(Date:2/11/2016)... , Feb. 11, 2016  Walgreens has committed ... 39 states and Washington, D.C. as ... move that was commended by shareholder advocacy organization As You ... As You Sow. "Many people hold on to unneeded drugs ... can have tragic consequences." --> Conrad MacKerron ...
(Date:2/11/2016)... FRANCISCO , Feb. 11, 2016   Health ... advancement of new health technologies, announced today " 10 ... achievements in health tech over the past ten years.   ... For nearly a decade, Health 2.0 has served as ... showcased and connected with thousands of technologies, companies, innovators, ...
Breaking Medicine Technology:
Cached News: