HOME >> MEDICINE >> NEWS
Are higher doses of cholesterol drugs worth the extra money? Only sometimes, study says

ANN ARBOR, Mich. -- When it comes to cholesterol-lowering drugs, more is better. At least, thats what heart doctors and heart patients have been hearing in recent years. And as a result, more patients are taking higher doses of drugs called statins leading to lower heart and stroke risk, but higher prescription drug costs and more frequent side effects.

Now, a new study looks at whether those higher doses, and higher costs, are really going to pay off for some patients. For those with a recent heart attack or what doctors call acute coronary syndrome, the answer is yes, the researchers say.

But the picture is less clear for those patients with known heart blockages who have stable symptoms. For them, the usual dose of their statin may provide adequate heart-protecting benefit, and the higher cost of high-dose statins may provide only marginal benefit at much greater cost, especially if they use generic statins.

The study, from a team at the University of Michigan Cardiovascular Center and the VA Ann Arbor Healthcare System, is published online in the journal Circulation, and will be in the May 8 print issue of the journal. Its based on a sophisticated computer analysis of data from thousands of patients.

The team finds that patients with a recent history of acute coronary syndrome (ACS) either a heart attack or hospital stay for chest pain get so much benefit from higher doses of statins (over four additional quality-adjusted months of life) that the extra cost of the increased dose is worthwhile, even if the difference is a few dollars a day.

But for patients with stable coronary artery disease (CAD), whose arteries have been narrowed by plaque but who havent had a recent heart attack or hospitalization for chest pain, the much smaller gain (about 5 weeks of quality-adjusted life) from a higher dose of a statin may not be sufficient to outweigh the extra cost.

The researchers also point out that
'"/>

Contact: Kara Gavin
kegavin@umich.edu
734-764-2220
University of Michigan Health System
23-Apr-2007


Page: 1 2 3 4 5

Related medicine news :

1. Women with migraines and visual symptoms may have higher stroke risk
2. Study explains why patients with OSA are at higher risk for cardiovascular disease
3. Tiny newborns face higher risk of death at community hospitals, Stanford/VA study finds
4. Persistent smokers may have higher risk to become depressed than never smokers
5. Veterans exposed to Agent Orange have higher rates of prostate cancer recurrence
6. Exposure to mercury preservatives before birth is no higher in children with autism
7. Post-traumatic stress disorder 10 times higher in New Orleans than in the general public
8. Uveal melanoma patients at higher risk for colon cancer
9. Girls born with HIV infection at higher risk for cervical problems
10. Detection of melanoma by dermatologists linked with earlier tumor stage, higher survival rates
11. Adoption of health information technology will lead to higher standard of quality care

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/23/2016)... ... 2016 , ... California State University Northridge (CSUN) psychology ... and is currently focusing on ways to improve how people treat under-represented groups. ... to find out whether watching them could have a significant anti-bias effect on ...
(Date:5/23/2016)... Wis. (PRWEB) , ... May 23, 2016 , ... ... April 29 on its Chesterfield, Missouri, campus, Standard Process Inc. awarded ... Cline, Stephanie Siewert and Chloe Tillman. Each student is in her fifth trimester ...
(Date:5/23/2016)... ... May 23, 2016 , ... Hospice of Westchester (HOW), an ... over 24 years, recently hosted its sixth annual Celebration of Life Memorial Butterfly ... ceremonies, each concluding with the release of Monarch butterflies that honored the memories ...
(Date:5/23/2016)... NY (PRWEB) , ... May 23, 2016 , ... ... the company’s top management team to meet the needs of its recent and ... to drive continued growth and business development across widening market segments. Max joined ...
(Date:5/23/2016)... PORT RICHEY, Fla. (PRWEB) , ... May 23, ... ... recently issued to address the nation’s prescription opioid epidemic (1), physicians are not ... are pursuing legislation at the state level (2, 3, 4). Novus Medical ...
Breaking Medicine News(10 mins):
(Date:5/23/2016)... , May 23, 2016 Global ... 163 pages, profiles 12 companies and the Paclitaxel analysis ... figures on the industry and its players. ... comprehensive in nature, details the current state of the ... including definitions, classifications, applications and industry chain structure. The ...
(Date:5/23/2016)... 2016 The World Health Organization (WHO) expanded the ... include adolescents aged 13 years, and above. Effective immediately, the ... adult and adolescent males in the 14 priority countries in ... the first male circumcision device to receive WHO Prequalification on ... Horowitz said: " The expanded use of ...
(Date:5/23/2016)... 2016   Purdue Pharma L.P.  today announced ... with Egalet Corporation and Acura Pharmaceuticals, Inc. that ... the agreement the companies will exchange valuable patent ... companies to develop and sell several opioid pain ... reflects the commitment of Purdue Pharma to seek ...
Breaking Medicine Technology:
Cached News: