HOME >> MEDICINE >> NEWS
Arranon cancer drug receives advisory committee support

HOUSTON Oncology patients received a small dosage of hope last week when Arranon (nelarabine) Injection, a cancer-fighting drug, was recommended for accelerated approval by the Oncologic Drugs Advisory Committee (ODAC) to the U.S. Food and Drug Administration (FDA). Arranon is targeted towards adult and pediatric patients fighting T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL), -- blood cancers that affect how the body makes blood and provides immunity from other diseases. The new drug, developed by GlaxoSmithKline (GSK), would be an option for patients whose disease has not responded to or has relapsed following at least two chemotherapy regimens.

Dr. Stacey Berg, co-director for Texas Children's Cancer Center clinical pharmacology group in Houston, led the Children's Oncology Group's (COG) phase 2 trial that played a major role in last week's recommendation for approval.

"The recommendation for accelerated approval is encouraging, particularly to pediatric oncologists," said Berg, who is an associate professor of pediatrics at Baylor College of Medicine. "There simply are not enough treatment options available for children with these particular cancers that often resist frontline therapy. If approved by the FDA, Arranon will give us the ability to offer more hope to our patients and their families."

In addition to the study in pediatric patients, a phase 2 study was conducted in adult patients by Cancer and Leukemia Group B (CALGB) in association with the Southwest Oncology Group (SWOG). Both of the adult and pediatric studies were sponsored by the Cancer Therapy Evaluation Program of the National Cancer Institute (NCI), under a Clinical Trials Agreement between NCI and GSK.

Pediatric cancer continues to be the second leading cause of death among children, behind accidental injury. Each school day, nine children die from the disease.

Texas Children's Cancer Center, located w
'"/>


29-Sep-2005


Page: 1 2

Related medicine news :

1. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
2. Survival differences by race most apparent in advanced stages of breast cancer
3. Stomach cancer rate set to fall further 25 percent over next decade
4. MRI finds breast cancer before it becomes dangerous
5. Investigators uncover intriguing clues to why persistent acid reflux sometimes turns into cancer
6. New cause of tamoxifen resistance in breast cancer cells discovered at Lombardi
7. Pathway links inflammation, angiogenesis and breast cancer
8. Using MRI for diagnosis could help prevent breast cancer progression
9. Electric fields have potential as a cancer treatment
10. Shining light on pancreatic cancer
11. Method shows promise for early detection of pancreatic cancer

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/6/2019)... ... ... TIME For Kids (TFK) revealed the first-ever list of the ... destinations that are tailored to the interests of kids. The list identifies The Children’s ... list, TIME for Kids gathered nominations from its network of TFK Kid Reporters ...
(Date:12/5/2019)... ... December 05, 2019 , ... Abide, the #1 Christian meditation and sleep ... year using Bible-based bedtime stories. Listeners have recovered from bad dreams and night terrors, ... for Disease Control, one third of Americans suffer from poor sleep, which is linked ...
(Date:12/5/2019)... ... December 05, 2019 , ... It’s been an impactful year ... help people embrace, achieve, and maintain a healthy lifestyle to giving generously to ... our mission of impacting world health, so it’s gratifying to look back on ...
(Date:12/4/2019)... ... December 04, 2019 , ... ... Extract®, provides protection from disruptions to cells and tissue and inflammation that leads ... Jet Lag, is available in a dietary supplement product called Prepair™ . ...
(Date:12/4/2019)... ... 2019 , ... While the holidays are a time for joy and sharing, ... AgriLife Extension Service specialists. , “There are many behavioral and logistical ... wellness,” said Joyce Cavanagh, AgriLife Extension specialist in family economics, College Station. , Prioritize ...
Breaking Medicine News(10 mins):
(Date:12/5/2019)... ... December 05, 2019 , ... nView, a leading behavioral ... the role of Chief Product Officer. As the company expands its portfolio of ... the behavioral health market into nView’s product and company growth strategy. Rosenbaum will ...
(Date:12/4/2019)... ... December 04, 2019 , ... Tenex ... minimally invasive technologies to treat chronic pain in soft and hard tissue, recently ... TX® technology. , Dr. Bernard Morrey, Chief Medical Officer of Tenex ...
(Date:12/4/2019)... ... December 04, 2019 , ... HGE Health, ... COPD patient’s symptoms, joined forces nearly a year ago with RespirCare, an operator ... care at times when the attention is most needed. The patient-satisfaction scores ...
Breaking Medicine Technology:
Cached News: