HOME >> MEDICINE >> NEWS
Arteries bio-engineered from elderly cells

DURHAM, N.C. Researchers from Duke University's Medical Center and Pratt School of Engineering have demonstrated that they can grow new human blood vessels from cells taken from patients who especially need such assistance older adults with cardiovascular disease.

The researchers said the results of their latest experiments represent a "proof of principle" for an approach that could be clinically applicable within five to ten years. The first to benefit from such bio-engineered arteries, according to lead researcher Laura Niklason, M.D., Ph.D., could be older patients with cardiovascular disease who need blockages in their arteries "bypassed" but do not have their own natural vessels available.

The results of the Duke experiments were published June 18, 2005, in the Lancet. The research was supported by the National Institutes of Health and the American Federation for Aging Research.

"There is a great need for viable alternatives to our current available options for treating patients with coronary artery or peripheral arterial disease," said Niklason, an associate professor of both anesthesiology and biomedical engineering. "In this current study, we took vascular cells from four elderly men with heart disease and engineered new blood vessels.

"The ability to grow new vessels from older cells represents a crucial initial step towards growing blood vessels from a patient's own cells that can be used to treat that patient's vascular disease," she continued.

In 1999, Niklason demonstrated she could grow new blood vessels in animal models by using a novel bioreactor she developed that mimics the fetal environment. When implanted back into the animals, the bioengineered vessels functioned like natural arteries. Unlike the cells in these experiments, however, human artery cells do not possess enough life cycles to be grown into functional arteries.

In collaboration with Duke cancer researcher Christopher Counter, Ph.D., an
'"/>

Contact: Richard Merritt
Merri006@mc.duke.edu
919-684-4148
Duke University Medical Center
16-Jun-2005


Page: 1 2 3

Related medicine news :

1. Warfarin better than aspirin at stroke prevention in elderly people with atrial fibrillation
2. Preventive treatments in elderly people needs rethinking
3. Refusal of medical and surgical interventions common among chronically ill elderly
4. Adding medication improves recovery for elderly with depression, says Pitt School of Medicine study
5. Research shows aerobic exercise helps maintain muscle in elderly
6. Spanish project AmIVital creates intelligent communication devices for elderly and disabled people
7. Decision making by the growing elderly population is uncharted territory
8. Study reveals depressed elderly risk early death
9. High-normal uric acid linked with mild cognitive impairment in the elderly
10. Nursing home or hospital: State policy has big impact on elderly
11. Treating prostate cancer in elderly men associated with longer survival, compared to non-treatment

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Apple ... care services, staged a mock evacuation of the facility as part of a disaster ... Fire Department, Echo Hose EMS and Shelton City Emergency Manager, as well as the ...
(Date:10/13/2017)... , ... October 13, 2017 , ... Global Healthcare Management’s ... Alexandria Park in Milford, NJ. This free event, sponsored by Global Healthcare Management’s ... The fun run is geared towards children of all ages; it is a ...
(Date:10/13/2017)... ... October 13, 2017 , ... “The Journey: From the ... danger possible to save lost souls in the Philippines. “The Journey: From the Mountains ... a dedicated teacher of the Bible. She has taught all ages and currently teaches ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and ... plans to open a flagship location in Covington, LA at 401 N. U.S. Highway ... store next to Office Depot in the Holiday Square shopping center. Its location allows ...
(Date:10/12/2017)... ... 2017 , ... Asante, a nationally recognized health system in ... existing home health joint venture through an agreement, effective October 1, 2017, to ... home health company with Asante, delivering clinically integrated care, for the past eight ...
Breaking Medicine News(10 mins):
(Date:10/10/2017)... -- NDS received FDA 510(k) clearance in May 2017 for its highly ... designed for endoscopy environments. An innovative secondary monitor solution, ZeroWire ... support the improvement of patient outcomes, procedural efficiency, and the lowering ... ... ...
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017  Eli Lilly and Company (NYSE: ... third quarter of 2017 on Tuesday, October 24, 2017. ... day with the investment community and media to further ... call will begin at 9 a.m. Eastern time. Investors, ... webcast of the conference call through a link that ...
Breaking Medicine Technology:
Cached News: