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BIDMC's Terry Strom, M.D., honored by American Society of Nephrology

vexing problem of organ rejection, the bodys natural immune response when faced with a "foreign invader." Through his work studying activated immune T-cells, Strom has been a leader in developing new approaches to overcome rejection without the use of highly toxic immunosuppressive drugs.

Beginning with basic studies of lymphocyte growth and development, Strom identified and characterized T-cell growth factors, produced reagents to block the action of these growth factors, studied them in experimental small animal models, evaluated them in primates, and participated in clinical trials.

His most recent work has focused on the influence of inflammation on the texture of transplant rejection and autoimmunity and on investigation of a family of T-cell proteins known as TIM (T-cell immunoglobulin Mucin domain), which serve as "checkpoints" for the survival or activation of T-cell subsets. To date, these findings have been published in the journals Nature, Nature Immunology and the Journal of Experimental Medicine.

A graduate of the University of Illinois School of Medicine, Strom went on to receive training in medicine at the University of Illinois Hospitals, at the former Beth Israel Hospital in Boston and at Bostons Peter Bent Brigham Hospital, where he later became medical director of the hospitals kidney transplant program. Strom is currently Professor of Medicine and Surgery at Harvard Medical School, where he has been teaching for more than three decades.

Throughout his career, Strom has contributed to more than 600 publications and has been honored with numerous awards including the Lilly Lectureship of the Royal College of Physicians (London), the 1997 Sandoz Transplant Established Investigator Award of the American Society of Transplant Physicians, and the 2001 Roche American Society of Transplantation Distinguished Achievement Award. A member of more than 15 professonal societies, Strom presently serves as a Councilor
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Contact: Bonnie Prescott
bprescot@bidmc.harvard.edu
617-667-7306
Beth Israel Deaconess Medical Center
4-Dec-2006


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