HOME >> MEDICINE >> NEWS
Bias in statin trials, failure to control malaria, and more

In this weeks press release:

  • Findings depend on who has funded the research

  • Vascular endothelial growth factor mediates intracrine survival in human breast carcinoma cells through internally expressed VEGFR 1/FLT1

  • Donors and international health agencies are failing Africa on malaria control

  • Teaching global health at the frontlines


Findings depend on who has funded the research

Research on the effectiveness of a major class of drug statins, used to reduce cholesterol has come under the spotlight in a new article published in PLoS Medicine. There are several statins now on the market and many research trials have compared different brands of statin head-to-head. The authors of the article looked at nearly 200 such trials, some were funded by governments, some by pharmaceutical companies, and in some cases the source of the funding had not been made clear. The authors found that trials of head-to-head comparisons were more likely to report results and conclusions favouring the sponsors own product than the drug with which it was compared

Lisa Bero and colleagues at the University of California, San Francisco argue that their findings show that the type of sponsorship available for randomized controlled trials of statins was strongly linked to the results and conclusions of those studies, even when other factors were taken into account. However, it is not clear from this study why sponsorship has such a strong link to the overall findings. There are many possible reasons why this might be. It has been suggested that drug companies may deliberately choose lower dosages for the comparison drug when they carry out head-to-head trials. Others have suggested that trials which produce unfavourable results are not published, or that unfavourable outcomes are suppressed. Whatever the reasons, the conclusions of this article are im
'"/>

Contact: Andrew Hyde
44-122-346-3330
Public Library of Science
4-Jun-2007


Page: 1 2 3 4 5 6

Related medicine news :

1. Could statins be a new option for hepatitis C patients?
2. Early statin therapy for patients with acute coronary syndromes reduces death, cardiovascular events
3. Patients can report statins adverse effects on new web site
4. UC Davis researchers find added benefit of statins in those at high risk for heart disease, diabetes
5. Popular statin reduces recurrent stroke risk
6. Cancer drug is first to alleviate devastating scleroderma symptoms
7. Early use of statins after coronary syndromes does not reduce risk of heart attack, stroke or death
8. Weekly religious attendance nearly as effective as statins and exercise in extending life
9. Very high-intensity statin therapy shows promise for inducing regression of coronary atherosclerosis
10. Intensive statin therapy may partially reverse plaque build-up in arteries
11. A protein fragment called 12.5 kda cystatin may generate first simple test for multiple sclerosis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:1/10/2019)... ... January 10, 2019 , ... Mount ... Chamber Music Society at the United Nations Staff Recreation Council in support of ... to provide complementary services including music, art, massage, and pet therapies to increase ...
(Date:1/10/2019)... (PRWEB) , ... January 10, 2019 , ... ... today that it has partnered with MD101, a regulatory consulting company that serves ... have core expertise in servicing companies in the medical device and healthcare industries. ...
(Date:1/10/2019)... ... 10, 2019 , ... GoGreen Hemp is excited to break ... CBD, or Cannabidiol, is one of many cannabinoids found in the hemp plant. ... that are naturally present in the body to produce desirable effects consistent with ...
(Date:1/8/2019)... NEW YORK (PRWEB) , ... January 08, 2019 , ... ... its new Hybrid-Responsive™ website: https://www.west10thdental.com . , According to Dr. Demetrios Sengos, founder ... striving to provide them with the latest in dental care by always keeping up ...
(Date:1/8/2019)... (PRWEB) , ... January 08, ... ... established leader in sterile compounding, announced that they now have Norepinephrine in ... Facility. These concentrated, sterile solutions (in concentrations that are not commercially available) ...
Breaking Medicine News(10 mins):
(Date:1/14/2019)... ... January 15, 2019 , ... Sigma Theta Tau International ... Book of the Year Awards. These awards are regarded as one of the most ... year, the AJN Book of the Year competition has recognized Sigma for the last ...
(Date:1/11/2019)... ... 11, 2019 , ... According to research, acupuncture can quickly and effectively treat ... now able to receive the respiratory treatment they need at its Houston clinic. , ... of imbalance as well. Acupuncture and Chinese Medicine can treat a wide range of ...
(Date:1/10/2019)... , ... January 10, 2019 , ... ... company providing nutrition and lifestyle solutions, will crown the U.S. winner of its ... 15 finalists include: Andrea Carrara of Palm Beach, Florida; Barbara Lingle of Winterville, ...
Breaking Medicine Technology:
Cached News: