HOME >> MEDICINE >> NEWS
Biopsy may underestimate prostate cancer in obese and overweight men

DURHAM, N.C. -- Obese and overweight men who are diagnosed with prostate cancer by biopsy are more likely than healthy weight men to actually have a more aggressive case of the disease than the biopsy results would indicate, according to a study led by a Duke University Medical Center researcher.

The finding suggests that misleading biopsy results may be causing many obese and overweight men to receive inadequate or inappropriate treatment that is not aggressive enough to combat the true nature of their disease, said study leader Stephen Freedland, M.D., an assistant professor in the Division of Urology and the Duke Prostate Center.

"We already know that its more difficult to diagnose prostate cancer in obese men because they have lower levels of prostate-specific antigen, or PSA, a common blood marker for prostate cancer, and because their larger-sized prostates make it more likely for a biopsy to miss the cancer," he said. "These findings further suggest that we could be missing even more high-grade disease among obese men."

Gaining a better understanding of links between biopsies and prostate cancer also may help physicians improve patient treatment, said Freedland, who also holds an appointment in surgery at the Durham Veterans Affairs Medical Center.

"If we can determine through additional biopsies that an obese or overweight man has more aggressive prostate cancer, we can discuss whether the cancer should be treated with more than one approach, such as combining hormonal therapy with radiation, to reduce the risk of the cancer spreading and improve the chances of cure," Freedland said. "We must also keep in mind that even if a well-done biopsy shows low-grade cancer in an obese patient, there is still a reasonable likelihood that the patient may have high-grade disease."

The researchers, from six universities, published the findings in the March 2007 issue of the journal Urology.

The study was fun
'"/>

Contact: Lauren Shaftel
lauren.shaftel@duke.edu
919-684-4966
Duke University Medical Center
27-Mar-2007


Page: 1 2 3

Related medicine news :

1. Mindless autopilot drives people to underestimate food decisions
2. Obesity levels in US are grossly underestimated
3. Snake bites should not be underestimated, say experts
4. Doctors and care providers often underestimate the full impact of head injuries
5. ESC emphasizes underestimated effects of tobacco use
6. Conventional prognostic factors fail to explain better prostate cancer survival in most Asian men
7. Trial shows circulating tumor cells predict how prostate cancer patients do with chemotherapy
8. African-American men understimate risk of prostate cancer
9. Treatment for early prostate cancer associated with type of specialist seen
10. Nonhormonal drug reduces hot flashes in men treated for prostate cancer
11. Flaxseed stunts the growth of prostate tumors

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:12/5/2018)... ... December 05, 2018 , ... Marking its seventh year, Pacifica ... “A Toast Heard ‘Round the World” on New Year’s Eve. Each year event ... community (alumni, students, faculty members, staff, families, and friends of the institution) to join ...
(Date:12/5/2018)... , ... December 05, 2018 , ... Northcentral University (NCU) ... of nursing. Available starting today and on a weekly rolling basis to registered nurses, ... Nursing Practice in Executive Leadership (DNP) will prepare degree candidates to become leaders ...
(Date:12/5/2018)... ... December 05, 2018 , ... To change the ... transformative conference at the DoubleTree Hilton Hotel in Newark, California. Led by world-renowned ... Founder/Director of Watson Caring Science Institute, participants and esteemed guests discussed the impact ...
(Date:11/29/2018)... ... ... “The total demand for technologies used in drug discovery reached approximately $4.9 billion ... project the market will grow at a healthy annual rate of 6.4% over the ... ages.” , This report details market activity in the areas of chromatography, sequencing, liquid ...
(Date:11/28/2018)... ... November 28, 2018 , ... CBD merchants throughout the United ... available. Previously, merchants were unable to obtain legitimate CBD processing accounts without being ... down their business after being put on the Visa and Mastercard processing blacklist. ...
Breaking Medicine News(10 mins):
(Date:11/28/2018)... CITY (PRWEB) , ... November 28, 2018 , ... nJoy ... high levels of myopia and astigmatism in one easy procedure following FDA approval of ... the Toric ICL, is scheduled at nJoy Vision OKC on November 29th by Edward ...
(Date:11/28/2018)... ATLANTA (PRWEB) , ... November 28, 2018 , ... ... to announce board certified reproductive endocrinologist Monica Best, M.D. has joined ... Mark Perloe, Desireé McCarthy-Keith, Anne Namnoum, and their most recent addition, Natalie Stentz. ...
(Date:11/28/2018)... ... November 28, 2018 , ... On ... Alliance of Pennsylvania, Ohio, and West Virginia (SimPOW) at their corporate headquarters in ... Suzan Kardong-Edgren and Dana Bargerstock were recognized in the opening session. Attendees enjoyed ...
Breaking Medicine Technology:
Cached News: