HOME >> MEDICINE >> NEWS
Blood clots can be treated by injections at home

Treatment of blood clots in the deep veins of the legs or the lungs with an older, less expensive form of the anticoagulant medication heparin can be just as safe and effective as similar treatment with a newer and more expensive heparin, according to a study led by Clive Kearon, professor of medicine at McMaster University, published in the August 23 issue of JAMA (The Journal of the American Medical Association).

When injected subcutaneously (beneath the skin), unfractionated (regular) heparin was shown in a randomized trial to work just as well as subcutaneous injection of the more expensive, low-molecular weight heparin in the treatment of venous thromboembolism. Traditionally, when unfractionated heparin is used in treatment, it is administered intravenously and accompanied by coagulation monitoring, which requires hospitalization. This standard approach includes ongoing dose adjustment in response to measurement of the APTT, a test that measures how fast the blood clots in a test tube under certain conditions.

The newer low-molecular weight heparins, which are administered by injection in fixed-weight doses, have gradually been replacing unfractionated heparin.

Kearon and colleagues conducted a randomized trial to study how fixed-dose, subcutaneous injection of unfractionated heparin compared to injection with the newer heparin in the treatment of blood clots in the legs or lungs.

The study was conducted from September 1998 through February 2004 at six university-affiliated clinical centres in Canada and New Zealand. Patients in the trial received either unfractionated or low-molecular-weight heparin administered subcutaneously every 12 hours. About 70 per cent of both groups were treated as outpatients. All patients received three months of warfarin (an anticoagulant drug) therapy.

Recurrent thromboembolism occurred in 3.8 per cent of the 345 patients in the unfractionated heparin group, and in 3.4 perce
'"/>

Contact: Veronica McGuire
vmcguir@mcmaster.ca
90-552-591-402-2169
McMaster University
22-Aug-2006


Page: 1 2

Related medicine news :

1. Blood inflammation plays role in Alzheimers disease
2. Blood-thinning drugs need closer monitoring
3. Blood transfusions from precancerous blood donors do not increase risk of cancer
4. Blood marker helps predict prognosis among those with abdominal infection
5. Blood transfusions raise heart patients infection and death risk -- especially women
6. Blood pressure drugs could help halt pancreatic cancer spread, Jefferson researchers find
7. Blood cells linked to heart attacks, other inflammatory diseases
8. Blood transfusion-transmitted infections: A global perspective
9. Blood pressure variability increases risk for stroke death
10. Blood pressure drugs associated with reduced risk of esophageal, pancreatic and colon cancers
11. Canadian Blood Services scientist invents potential alternative for high-demand blood product

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/19/2019)... ... 2019 , ... In one of the first research studies ... team led by a Worcester Polytechnic Institute professor found that women who experience ... weight gain during pregnancy, and weight retention after their baby is born. , ...
(Date:2/19/2019)... ... 19, 2019 , ... Pneumatic Vacuum Elevators, LLC has published ... on how-to make a house handicap accessible. , With this infographic , ... house handicap accessible. To accurately educate consumers on handicap accessibility, the infographic ...
(Date:2/19/2019)... ... February 19, 2019 , ... Hospice of Westchester (HOW) ... The funds will support the heart of its operation, the organization’s Home Care Services. ... years, and we are grateful for their ongoing generosity,” said Mary K. Spengler, MS, ...
(Date:2/19/2019)... ... February 19, 2019 , ... ... Endorsed Program that offers competitive student loan refinancing as a new member benefit. ... dentist may face. The average educational debt for all indebted graduates in the ...
(Date:2/19/2019)... ... February 19, 2019 , ... NCPDP announced today that ... patient engagement, will deliver the luncheon keynote on Tuesday, May 7, at ... medicine and empowering partnerships between patients and their medical providers to NCPDP’s Annual ...
Breaking Medicine News(10 mins):
(Date:2/19/2019)... ... February 19, 2019 , ... ... and the International Dyslexia Association estimates that there are 1 billion people with ... Global Search for Education and founder of CMRubinWorld, Fredrik Wetterhall, the co-founder of ...
(Date:2/19/2019)... ... February 19, 2019 , ... TopConsumerReviews.com recently gave its best-in-class 5 star ... prevent Lice. , Lice outbreaks are surprisingly common, especially in schools and other environments ... lice is not a sign of uncleanliness; in fact, lice prefer to live on ...
(Date:2/19/2019)... N.J. (PRWEB) , ... February ... ... applications and infrastructure solutions provider for global service providers, enterprises, and developers, ... and orchestration platform with the Arvizio MR Studio mixed reality visualization and ...
Breaking Medicine Technology:
Cached News: