HOME >> MEDICINE >> NEWS
Brain structure changes years before memory loss begins

ST. PAUL, Minn People who develop dementia or Alzheimer's disease experience brain structure changes years before any signs of memory loss begin, according to a study published in the April 17, 2007, issue of Neurology, the scientific journal of the American Academy of Neurology. Researchers say these findings may help identify people at risk of developing mild cognitive impairment (MCI), which leads to Alzheimer's disease.

Researchers performed brain scans and cognitive tests on 136 people over the age of 65 who were considered cognitively normal at the beginning of the five-year study. Participants were then followed annually with neurologic examination and extensive mental status testing. By the end of the study, 23 people had developed MCI, and nine of the 23 went on to be diagnosed with Alzheimer's disease. The brain scans of the 23 people with memory loss were then compared to the 113 people who remained cognitively normal.

Compared to the group that didn't develop memory problems, the 23 people who developed MCI or Alzheimer's disease had less gray matter in key memory processing areas of their brains even at the beginning of the study when they were cognitively normal.

"We found that changes in brain structure are present in clinically normal people an average of four years before MCI diagnosis," said study author Charles D. Smith, MD, with the University of Kentucky Medical Center in Lexington and member of the American Academy of Neurology. "We knew that people with MCI or Alzheimer's disease had less brain volume, but before now we didn't know if these brain structure changes existed, and to what degree, before memory loss begins."

In addition, the study found those people destined to develop MCI had lower cognitive test scores at the beginning of the study compared to the group that didn't develop memory problems, even though these scores were still within normal range.

"These findings of structural
'"/>

Contact: Angela Babb
ababb@aan.com
651-695-2789
American Academy of Neurology
16-Apr-2007


Page: 1 2

Related medicine news :

1. Brain-boosting pill alleviates post-chemotherapy fogginess
2. Brain inflammation may be friend, not foe, for Alzheimers patients
3. Brain activity reflects differences in types of anxiety
4. Brain research poised to dramatically advance global society
5. Elsevier announces launch of Brain Stimulation
6. Brains scans of symptomatic Gulf War veterans show differences
7. Brain studies reveal the mechanisms of the voluntary control of visual attention
8. Brains can recover from alcoholic damage but patients should stop drinking as soon as possible
9. Brain images show hysteria not an imaginary disorder
10. Brain changes in patients with migraine
11. Brain cell and face perception research wins Eppendorf/Science Prize

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, CA ... the Road To Recovery® program to drive cancer patients to and from their cancer ... ensure the highest quality of life and ongoing independence. Getting to and from ...
(Date:6/24/2016)... ... June 24, 2016 , ... People across the U.S. are sharpening their ... Award, an essay contest in which patients and their families pay tribute to a ... the 2016 National Society of Genetic Counselors (NSGC) Annual Education Conference (AEC) this September. ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... ... Living, is proud to recognize Dr. Barry M. Weintraub as a prominent plastic ... most beautiful women in the world, and the most handsome men, look naturally ...
(Date:6/24/2016)... Maryland (PRWEB) , ... June 24, 2016 , ... ... Angels is actively feeding the Frederick area economy by obtaining investment capital for ... over the past 2½ years that have already resulted in more than a ...
(Date:6/24/2016)... ... ... Venture Construction Group (VCG) sponsors Luke’s Wings 5th ... Woodmont Country Club at 1201 Rockville Pike, Rockville, Maryland, 20852. The event raised ... have been wounded in battle and their families. Venture Construction Group is a 2016 ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... ANGELES , June 23, 2016 ... CAPR ), a biotechnology company focused ... therapeutics, today announced that patient enrollment in its ... in Duchenne) has exceeded 50% of its 24-patient ... enrollment in the third quarter of 2016, and ...
(Date:6/23/2016)... , , , WHEN: , , ... , , , LOCATION: , , , Online, with free registration ... PANELISTS:  , , , Frost & Sullivan,s Global Vice President of ... Analyst, Divyaa Ravishankar and Unmesh Lal, Program Manager , ... witnessing an exceptional era. Several new demand spaces, such as innovative ...
(Date:6/23/2016)... , June 23, 2016 ... Oticon , industry leaders in advanced ... launch of Oticon Opn ™, the world,s first ... of possibilities for IoT devices.      (Photo: ... Oticon introduces a number of ,world firsts,: ...
Breaking Medicine Technology:
Cached News: