HOME >> MEDICINE >> NEWS
Breath test offers hope for early detection of lung-bacteria growth in cystic fibrosis

atory deterioration and mortality. Over time, the bacteria transforms into treatment-resistant variants, and early detection is seen as key for aggressive antibiotic treatments to delay its growth.

In the study, graduate student Michael Kambourse, working with Blake and Rowland, examined exhaled breath from people with and without cystic fibrosis using laboratory methods developed for their atmospheric chemistry work. In that work, they measure the levels of trace gases in excess of the parts-per-billion range that contribute to local and regional air pollution. Their research group is one of the few in the world recognized for its ability to measure accurately at such small amounts.

In analyzing the breath samples, the researchers monitored levels of three sulfides in the cystic fibrosis patients -- carbonyl sulfide, dimethylsulfide and carbon disulfide. Significantly, they found that cystic fibrosis patients exhaled carbonyl sulfide (OCS) at rates up to 2 times higher than people who don't have the disease, making it an attractive target for future breath analysis.

The study determined that the regular air the test subjects breathed in had about 600 parts-per-trillion volume (pptv) of OCS. The non-cystic fibrosis subjects exhaled a mean average of 350 pptv of OCS, meaning that about 250 pptv of OCS was removed from the inhaled air. The cystic fibrosis subjects exhaled a mean average 490 pptv of OCS, and the three individuals with the weakest pulmonary function exhaled as much as 800 pptv, producing an excess of OCS. This suggests a substantial OCS source, probably bacterial, exists in their lungs, in addition to poorer processing of inhaled gas.

The researchers are continuing their breath-analysis work in areas of autism, diabetes and oral glucose tolerance testing. Most relevant are ongoing studies in which they are testing the profile of gases produced by bacteria, like P. aeruginosa.

"The ultra-trace gas breath analysis tec
'"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
17-Oct-2005


Page: 1 2 3

Related medicine news :

1. Breathing problems during sleep increase risk of depression
2. Breathing exercises can significantly cut inhaler use in mild asthma
3. Breath of the dragon: ERS-2 and Envisat reveal impact of economic growth on Chinas air quality
4. Breathing disorders during sleep are common among asthmatics, may help predict severe asthma
5. Hormone therapy offers new hope for ovarian cancer patients
6. TB test offers patients quicker and easier diagnosis
7. Panel offers guidelines on skin reactions to new class of cancer drugs
8. Supersize me mice research offers grim warning for Americas fast food consumers
9. New treatment offers relief from chronic back pain
10. Commonly used drug offers promise for premature babies
11. Stenting of abdominal arteries offers welcome relief for intestinal angina

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... June 27, 2016 , ... ... health professionals, announced today its affiliation with Tennessee Counseling Association. This ... the network of the Tennessee Counseling Association, adding exclusive benefits and promotional offers. ...
(Date:6/26/2016)... ... June 26, 2016 , ... On June 10-11, 2016, A ... 2016 Cereal Festival and World’s Longest Breakfast Table in Battle Creek, MI, where the ... history as home to some of the world’s leading providers of cereal and other ...
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... ... June 25, 2016 , ... As a lifelong Southern Californian, Dr. Omkar Marathe ... from the David Geffen School of Medicine at UCLA. He trained in Internal Medicine ... his fellowship in hematology/oncology at the UCLA-Olive View-Cedars Sinai program where he had the ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Research and ... Market for Companion Diagnostic Tests" report to their offering. ... for Companion Diagnostics The World Market for ... personalized medicine diagnostics. Market analysis in the report includes the ... Market (In Vitro Diagnostic Kits) by Region (N. America, EU, ...
(Date:6/23/2016)... , June 23, 2016  MedSource announced ... as its e-clinical software solution of choice.  This ... best possible value to their clients by offering ... The preferred relationship establishes nowEDC as the EDC ... for MedSource,s full-service clients.  "nowEDC has long been ...
(Date:6/23/2016)... , June 23, 2016 Roche (SIX: RO, ... clearance for its Elecsys BRAHMS PCT (procalcitonin) assay as ... or septic shock. With this clearance, Roche is the ... fully integrated solution for sepsis risk assessment and management. ... bacterial infection and PCT levels in blood can aid ...
Breaking Medicine Technology:
Cached News: