HOME >> MEDICINE >> NEWS
Breath test offers hope for early detection of lung-bacteria growth in cystic fibrosis

atory deterioration and mortality. Over time, the bacteria transforms into treatment-resistant variants, and early detection is seen as key for aggressive antibiotic treatments to delay its growth.

In the study, graduate student Michael Kambourse, working with Blake and Rowland, examined exhaled breath from people with and without cystic fibrosis using laboratory methods developed for their atmospheric chemistry work. In that work, they measure the levels of trace gases in excess of the parts-per-billion range that contribute to local and regional air pollution. Their research group is one of the few in the world recognized for its ability to measure accurately at such small amounts.

In analyzing the breath samples, the researchers monitored levels of three sulfides in the cystic fibrosis patients -- carbonyl sulfide, dimethylsulfide and carbon disulfide. Significantly, they found that cystic fibrosis patients exhaled carbonyl sulfide (OCS) at rates up to 2 times higher than people who don't have the disease, making it an attractive target for future breath analysis.

The study determined that the regular air the test subjects breathed in had about 600 parts-per-trillion volume (pptv) of OCS. The non-cystic fibrosis subjects exhaled a mean average of 350 pptv of OCS, meaning that about 250 pptv of OCS was removed from the inhaled air. The cystic fibrosis subjects exhaled a mean average 490 pptv of OCS, and the three individuals with the weakest pulmonary function exhaled as much as 800 pptv, producing an excess of OCS. This suggests a substantial OCS source, probably bacterial, exists in their lungs, in addition to poorer processing of inhaled gas.

The researchers are continuing their breath-analysis work in areas of autism, diabetes and oral glucose tolerance testing. Most relevant are ongoing studies in which they are testing the profile of gases produced by bacteria, like P. aeruginosa.

"The ultra-trace gas breath analysis tec
'"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
17-Oct-2005


Page: 1 2 3

Related medicine news :

1. Breathing problems during sleep increase risk of depression
2. Breathing exercises can significantly cut inhaler use in mild asthma
3. Breath of the dragon: ERS-2 and Envisat reveal impact of economic growth on Chinas air quality
4. Breathing disorders during sleep are common among asthmatics, may help predict severe asthma
5. Hormone therapy offers new hope for ovarian cancer patients
6. TB test offers patients quicker and easier diagnosis
7. Panel offers guidelines on skin reactions to new class of cancer drugs
8. Supersize me mice research offers grim warning for Americas fast food consumers
9. New treatment offers relief from chronic back pain
10. Commonly used drug offers promise for premature babies
11. Stenting of abdominal arteries offers welcome relief for intestinal angina

Post Your Comments:
(Date:7/23/2014)... or itchy skin lesions could be a warning sign ... multiple lesions that are suspicious looking, and those that ... non-melanoma skin cancers," study author Dr. Gil Yosipovitch, chairman ... in a Temple University Health System news release. ... who were confirmed to have skin cancer lesions between ...
(Date:7/23/2014)... Agricultural and Forestry University in Shaanxi province, and the ... agreement that lays the groundwork for establishing the Sino-U.S. ... The signing ceremony was held in the city of ... the U.S. Department of Agriculture and China,s Ministry of ... event for UC Davis and for our World Food ...
(Date:7/23/2014)... 2014 The American Telemedicine Association ... twentieth annual meeting and tradeshow focused exclusively on ... attract over 5,000 attendees and more than 250 ... 3-5, 2015, in Los Angeles. , ATA’s annual ... professionals from researchers, clinicians, hospital and university administrators, ...
(Date:7/23/2014)... Bodybuilding.com, the Internet’s most-visited bodybuilding and ... supplements, has officially opened the polls for their tenth ... fastest growing sports nutrition company, is up for eight ... Year, Best Tasting Protein of the Year- Whey-HD™, Most ... year - Whey-HD™, Pre-workout Supplement of the Year - ...
(Date:7/23/2014)... The voice on the recording was low and calm as the ... infected with the human immunodeficiency virus (HIV) that causes AIDS: “My ... know I was on the floor flat on my face boohooing, ... the recording ended less than 10 minutes later. “Don’t feel like ... it is just God setting you up for something greater,” the ...
Breaking Medicine News(10 mins):Health News:Painful, Itchy Patches Could Be Sign of Skin Cancer 2Health News:Global food safety research agreement signed by China and UC Davis 2Health News:Global food safety research agreement signed by China and UC Davis 3Health News:ATA Seeks Speakers to Present at the World’s Largest Telemedicine, mHealth and Telehealth Conference 2Health News:Vote Now; BPI SPORTS is Nominated for Eight 2014 Bodybuilding.com Supplement Awards 2Health News:Vote Now; BPI SPORTS is Nominated for Eight 2014 Bodybuilding.com Supplement Awards 3Health News:HIV clinic-based audio project emphasizes the power of patient voices 2Health News:HIV clinic-based audio project emphasizes the power of patient voices 3
(Date:7/23/2014)... -- The Board of Directors of VirtualScopics, Inc. (NASDAQ: ... trial imaging solutions, announced today that Eric T. ... executive officer, effective immediately.  Mr. Converse joined the company,s ... the positions of interim president and chief executive officer ... E. Phelps , Ph.D., chairman of the company,s Board ...
(Date:7/23/2014)... Wis. and MOUNTAIN VIEW, Calif. ... ("Surpass"), a recognized leader in translational preclinical research, today ... www.surpassinc.com ), signaling the transformation of Surpass, corporate ... innovation partner for our customers. This press release comes ... two integral hires were added to the Silicon Valley ...
(Date:7/23/2014)... 23, 2014 Pharmavite LLC announced that Timothy ... officer effective immediately. Toll recently served as Pharmavite,s executive ... category management, private label and sales administration in ... global role, Toll will expand his responsibilities to include ... "Toll,s appointment to chief customer officer is part ...
Breaking Medicine Technology:Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 2Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 3Eric T. Converse Named President And Chief Executive Officer Of VirtualScopics, Inc. 4SURPASS Launches New Company Logo and Corporate Website, Symbolizing Transformation of Company Culture to Meet the Changing Needs of Clients in the Life Science Community Today. 2SURPASS Launches New Company Logo and Corporate Website, Symbolizing Transformation of Company Culture to Meet the Changing Needs of Clients in the Life Science Community Today. 3
Cached News: