HOME >> MEDICINE >> NEWS
Breath test offers hope for early detection of lung-bacteria growth in cystic fibrosis

atory deterioration and mortality. Over time, the bacteria transforms into treatment-resistant variants, and early detection is seen as key for aggressive antibiotic treatments to delay its growth.

In the study, graduate student Michael Kambourse, working with Blake and Rowland, examined exhaled breath from people with and without cystic fibrosis using laboratory methods developed for their atmospheric chemistry work. In that work, they measure the levels of trace gases in excess of the parts-per-billion range that contribute to local and regional air pollution. Their research group is one of the few in the world recognized for its ability to measure accurately at such small amounts.

In analyzing the breath samples, the researchers monitored levels of three sulfides in the cystic fibrosis patients -- carbonyl sulfide, dimethylsulfide and carbon disulfide. Significantly, they found that cystic fibrosis patients exhaled carbonyl sulfide (OCS) at rates up to 2 times higher than people who don't have the disease, making it an attractive target for future breath analysis.

The study determined that the regular air the test subjects breathed in had about 600 parts-per-trillion volume (pptv) of OCS. The non-cystic fibrosis subjects exhaled a mean average of 350 pptv of OCS, meaning that about 250 pptv of OCS was removed from the inhaled air. The cystic fibrosis subjects exhaled a mean average 490 pptv of OCS, and the three individuals with the weakest pulmonary function exhaled as much as 800 pptv, producing an excess of OCS. This suggests a substantial OCS source, probably bacterial, exists in their lungs, in addition to poorer processing of inhaled gas.

The researchers are continuing their breath-analysis work in areas of autism, diabetes and oral glucose tolerance testing. Most relevant are ongoing studies in which they are testing the profile of gases produced by bacteria, like P. aeruginosa.

"The ultra-trace gas breath analysis tec
'"/>

Contact: Tom Vasich
tmvasich@uci.edu
949-824-6455
University of California - Irvine
17-Oct-2005


Page: 1 2 3

Related medicine news :

1. Breathing problems during sleep increase risk of depression
2. Breathing exercises can significantly cut inhaler use in mild asthma
3. Breath of the dragon: ERS-2 and Envisat reveal impact of economic growth on Chinas air quality
4. Breathing disorders during sleep are common among asthmatics, may help predict severe asthma
5. Hormone therapy offers new hope for ovarian cancer patients
6. TB test offers patients quicker and easier diagnosis
7. Panel offers guidelines on skin reactions to new class of cancer drugs
8. Supersize me mice research offers grim warning for Americas fast food consumers
9. New treatment offers relief from chronic back pain
10. Commonly used drug offers promise for premature babies
11. Stenting of abdominal arteries offers welcome relief for intestinal angina

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:10/13/2017)... TX (PRWEB) , ... October 13, 2017 , ... ... planning agency serving communities in the greater Dallas, Miami, and Raleigh regions, is ... boy fighting to overcome a rare and deadly chromosome abnormality. , After struggling ...
(Date:10/13/2017)... ... 13, 2017 , ... While it’s often important to take certain medications during ... Austin, Texas, has identified a solution. , She developed a prototype for MOTION LIGHT-UP ... such, it eliminates the need to turn on a light when taking medication during ...
(Date:10/13/2017)... ... ... PurhealthRX , a leading Health and Nutrition Company, is announcing the ... spectrum CBD oil will revolutionize the rapidly growing CBD market by reducing the amount ... into liquid products, while reducing costs to end users. , The team of researchers ...
(Date:10/13/2017)... ... ... Apple Rehab Shelton Lakes , which specializes in the delivery of sub-acute ... of a disaster drill on October 3rd. , Apple Rehab participated with the Shelton ... well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). The LTC-MAP ...
(Date:10/13/2017)... ... October 13, 2017 , ... Ellevate Network, the leading network for ... for action towards gender equality at their inaugural Summit in New York City in ... reached a social audience of over 3 million. To watch the Mobilize Women video, ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Oct. 12, 2017 AVACEN Medical , Inc. ... with their  2017 New Product Innovation Award for Its ... primary and secondary medical device market research by Frost & ... first-to-market OTC, drug-free pain relief product, the AVACEN 100, offers ... treating fibromyalgia widespread pain. ...
(Date:10/11/2017)... 11, 2017  Caris Life Sciences ® , a ... promise of precision medicine, today announced that St. Jude ... Oncology Alliance™ (POA) as its 17 th member. ... Jude Crosson Cancer Institute will help develop standards of ... tumor profiling, making cancer treatment more precise and effective. ...
(Date:10/10/2017)... --  West Pharmaceutical Services, Inc. (NYSE: WST), a ... today shared the results of a study highlighting the ... administration of polio vaccines. The study results were presented ... by Dr. Ondrej Mach , Clinical Trials and ... and recently published in the journal Vaccine. i ...
Breaking Medicine Technology:
Cached News: