HOME >> MEDICINE >> NEWS
Brief, high-dose steroid treatment offers extended relief to giant cell arteritis patients

ATLANTA -- A new study offers both hope and a practical treatment option for patients with giant cell arteritis (GCA). Researchers from Emory University and the Mayo Clinic have found that by treating newly diagnosed GCA patients with just three days of a high-dose intravenous steroid, patients relapsed less in the following year and were able to significantly taper off usage of an oral steroid. The study is published in the October issue of the journal Arthritis & Rheumatism.

Giant cell arteritis is characterized by inflammation of arteries, primarily in the head, and affects 20 out of every 100,000 people. GCA inflammation may lead to swelling and headaches, or, as it progresses, vision loss, strokes and aortic aneurysms. While past research has shown a genetic link to the disease, which primarily affects Caucasian women over the age of 50, there is no known cause or cure.

For the last 40 years, physicians have been able to treat and reverse some symptoms of GCA by prescribing prednisone, to be taken daily over a year or more. "Patients improve promptly and reliably, within days of when we treat them," says Cornelia M. Weyand, MD, PhD, co-director of the Kathleen B. and Mason I. Lowance Center for Human Immunology at Emory University and an author of the paper. "The problem is that patients have to take prednisone for a long time and in high doses, and they are at risk of developing side effects." Common side effects include hypertension, diabetes and osteoporosis.

While scientists have attempted to develop new drugs that would be more effective and have fewer side effects, their results have been unsuccessful. "We and others tried to look into other types of treatments that could help with this disease," says Jrg Goronzy, MD, PhD, senior author of the paper, and co-director of the Lowance Center.

"Even the modern and effective immunosuppressants do not improve the situation with these patients," says Dr. Weyan
'"/>

Contact: Holly Korschun
hkorsch@emory.edu
404-727-3990
Emory University Health Sciences Center
2-Oct-2006


Page: 1 2

Related medicine news :

1. Study examines characteristics of female high school students who report steroid use
2. Female teen steroid use not limited to athletes
3. Bronchial thermoplasty may allow severe asthma patients to wean off oral corticosteroids
4. Inhaled steroids may not be enough for some children with asthma
5. Nonsteroidal anti-inflammatory drugs use associated with higher gastrointestinal complications
6. Short-term topical corticosteroid use may offer relief for patients with acute form of psoriasis
7. Pre-clinical study suggests how steroid can reverse post-traumatic stress
8. Inhaled corticosteroids reduce death in patients with COPD
9. Non-steroidal anti-inflammatory drugs (NSAIDs) and congenital anomalies
10. National trial gives unprecedented support for steroid withdrawal in kidney transplants
11. New study adds weight to argument for steroid injections in patients with hip osteoarthritis

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/24/2017)... Houston, TX (PRWEB) , ... February 24, 2017 ... ... now offering promotions on tooth replacement options at his office, Antoine Dental Center. ... dental implants for $18,499. Some restrictions may apply, but patients can learn more ...
(Date:2/24/2017)... ... February 24, 2017 , ... WHAT: , The ... recognition opportunities as well as advocacy for the state and region‘s technology businesses, ... 23. The Council's Innovation Forecast event highlights innovation throughout the region from ...
(Date:2/24/2017)... ... ... Dr. Ronald E. Hawkins, vice president for academic affairs ... Bell, DO, MBA, HPF, FACOEP-dist., FACEP, as the new dean of Liberty ... to Liberty from the Ohio University Heritage College of Osteopathic Medicine (OU-HCOM), where ...
(Date:2/24/2017)... ... February 24, 2017 , ... In the Health Care IT ... top priority because it’s not if you will be attacked, but when.” However, he ... comes to digital health care. , Improvements in auditing and monitoring have taken security ...
(Date:2/24/2017)... ... 2017 , ... Healthcare Associates of McKinney announced today that they ... 8080 State Highway 121, Suite 210, McKinney, Texas 75070. It is in the ... As the practice has grown, the need for more space has been paramount. ...
Breaking Medicine News(10 mins):
(Date:2/27/2017)... 2017 Mederi Therapeutics today announced the ... 2468 patients who received  Stretta Therapy  to treat ... Systematic Review and Meta-Analysis of Controlled and Prospective ... of Gastroesophageal Reflux Disease ", was published in ... , MD, head of the Esophageal and Swallowing ...
(Date:2/27/2017)... Fla. , Feb. 27, 2017 ... focused on developing cerebral embolic protection devices for ... the FDA,s Circulatory System Devices Panel that convened ... need for cerebral protection following transcatheter aortic valve ... by this FDA panel support the need for ...
(Date:2/27/2017)... Feb. 27, 2017  Impax Laboratories, Inc. (NASDAQ: IPXL ) today ... Raymond James and Associates, 38 th ... 2017 in Orlando, FL. Cowen ... ET on March 7, 2017 in Boston, MA. ... 16, 2017 in Miami, FL. ...
Breaking Medicine Technology:
Cached News: