Call for greater use of comparative effectiveness studies to help advance disease management

Porto [March, 31st 2007]. The largest retrospective, observational study comparing two osteoporosis therapies on the basis of fracture reduction was presented today at the Seventh European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ECCEO) in Porto, Portugal.1 Patients taking the osteoporosis treatment risedronate (Actonel, risedronate sodium) were almost half as likely to sustain a hip fracture as those taking alendronate in the first year of treatment, according to the REAL (RisedronatE, ALendronate) study.

Only a few "head-to-head" observational studies, or comparative effectiveness studies, have been conducted in the field of osteoporosis. Beyond the safety and efficacy data provided by placebo-controlled randomized trials, healthcare professionals have increasingly expressed interest in more head-to-head data comparing therapies on the relevant clinical endpoint, fracture.

Comparative effectiveness filling the knowledge gap

Today experts are highlighting that well-designed comparative effectiveness studies can help advance our clinical knowledge where little data exists. Dr. Olaf Klungel, Associate Professor, Division of Pharmacoepidemiology and Pharmacotherapy, University of Utrecht, Netherlands, is a leading expert in the field of comparative effectiveness study design.

"There is a wealth of data available from large healthcare databases that enable us to research important clinical questions," said Dr. Klungel, "Robust methodology exists for comparing different therapies through observational database analysis. We must advance physicians' understanding and evaluation of these studies so that they can confidently integrate the information into their clinical decisions, when appropriate."

Physicians want to know the impact of their clinical decisions on the disease outcomes that matter most to patients. In the cardiovascular area, observational methods have been appl

Contact: Lucie Burns

Page: 1 2

Related medicine news :

1. Childhood obesity indicates greater risk of school absenteeism, Penn study reveals
2. Small infants have greater survival rate in high level intensive care facilities
3. Full-term, low-birth-weight babies at significantly greater risk for early respiratory symptoms
4. Teens with migraine at greater risk of suicide
5. Task force recommends greater use of exercise testing in chronic disease
6. Anthrax attack posed greater potential threat than thought
7. Nonprofit hospitals, more nurses and greater availability of technology equal better patient care
8. Underweight women at greater risk of miscarriage
9. Adolescent smokers have a greater risk of developing alcohol-use disorders than nonsmokers
10. Friends have greater sway on college students beliefs on drinking behavior
11. Binge-drinking teenagers at greater risk of violence

Post Your Comments:

(Date:8/31/2020)... ... , ... Just found out your dear friend has cancer? , It’s hard to hear your ... shares their diagnosis. Once the shock wears off, the questions and fears can be overwhelming. ... best ways to help? Words are failing me. I’m scared. I want to DO something. ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... In an effort to give back to ... 10 percent of each hotel room booked with a special new rate code to ... Indiana (RMHC-CNI) , effective immediately. Donations will be applied to any room type, ...
(Date:8/28/2020)... ... 28, 2020 , ... Ernst & Young LLP (EY US) ... Of The Year® 2020 Florida Award finalist. Now in its 34th year, the ... growth and prosperity as they build and sustain successful businesses that transform our ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Integrated ... Miami is the first Florida school to deploy its breakthrough Mobile Biodefense Indoor Air ... airborne COVID-19. True North Classical Academy plans to fully reopen equipped with the filtration ...
Breaking Medicine News(10 mins):
(Date:9/1/2020)... ... September 01, 2020 , ... While coronavirus cases continue to increase across ... and community organizations remain closed. Because about 80% of blood donations are made at ... blood donors and blood drive hosts to ensure blood products are readily available for ...
(Date:8/31/2020)... (PRWEB) , ... August 31, 2020 , ... If you live in New York City ... real estate part makes sense, it’s the law of supply and demand, but are plastic ... has a significant percentage of their patients that make the four-hour trip to have ...
(Date:8/28/2020)... (PRWEB) , ... August 28, 2020 , ... Dr. ... reproductive and endoscopic surgeon and serves as a clinical professor in the Department of ... of the American Laparoscopy Society & Pacific Coast Reproductive Society and is a Clinical ...
Breaking Medicine Technology:
Cached News: