TWO STUDIES ON BROCCOLI SPROUTS YIELD FINDINGS ON GASTRITIS AND SKIN CANCER
(Embargoed for Release until 9 AM, ET, Monday, October 31, 2005)
Abstracts #2597 and #3442
Researchers in Japan and Baltimore have found that a daily serving of broccoli sprouts can improve chronic bacterial gastritis, a serious disorder that causes inflammation of the stomach lining. Without treatment, gastritis may lead to ulcers and in some cases, stomach cancer.
Unlike the green, treelike florets common on dinner plates, three-day-old sprouts from broccoli seeds contain ultra high concentrations of sulforaphane, a compound with documented cancer prevention effects. Now, Hopkins investigators say there is some evidence the compound has antibiotic properties to treat the bacteria that causes gastritis. Forty research participants in Japan were randomly assigned to eat 100 grams daily (enough to fill the palm of a hand) of either broccoli sprouts or a sulforaphane-free vegetable. Researchers measured levels of blood proteins that are specific indicators of gastritis and inflammation, and they measured participants' stomach colonization with the bacterium Helicobacter pylori. This year's Nobel Prize in Medicine went to the scientists who some years ago demonstrated that stomach ulcers are almost always caused by H. pylori infection, and that a course of antibiotics could cure most of them.
"The indicators of bacterial infection and gastritis were significantly reduced in the group that ate broccoli sprouts," says Jed Fahey, M.D.,
Contact: Vanessa Wasta
Johns Hopkins Medical Institutions