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Cancer researchers describe gene that halts spread of aggressive childhood cancer

roadmap for attacking not just the primary cancer but the metastatic cascade, the metastatic disease process, as well," said Cheresh. "That is new, and very exciting. We now know the Achilles heel of the metastatic tumor cell. If we can develop drugs targeted at restoring caspase 8, we may be able to stop metastasis. That now appears feasible."

The study was co-authored by a team from St. Jude that included Tal Teitz, Ph.D., Peter Houghton, M.D., and Jill Lahti, Ph.D., as well as by UCSD scientists Matthew Potter, Ph.D., and David Mikolon. Lahti, the senior scientist in the St. Jude group, has collaborated with Stupack for several years.


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Contact: Nancy Stringer
healthscicomm@ucsd.edu
619-543-6163
University of California - San Diego
4-Jan-2006


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