HOME >> MEDICINE >> NEWS
Causes of primary biliary cirrhosis

A case-control study of more than 2000 people has identified a number of factors that may induce primary biliary cirrhosis (PBC) in genetically susceptible individuals. These include a history of urinary tract infections, hormone replacement therapy, tobacco use, and nail polish use. The study is published in the November 2005 issue of Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD). Published by John Wiley & Sons, Inc., Hepatology is available online via Wiley InterScience at http://www.interscience.wiley.com/journal/hepatology.

PBC is a rare autoimmune disease which leads to liver failure. The cause of the disease is unknown. It is more prominent in women, and researchers have found instances of familial clustering, as well as association with urinary tract infections, tobacco smoking, and estrogen use, though some of the existing studies have offered conflicting evidence.

To better understand the origins of the disease, researchers, led by M. Eric Gershwin, M.D. of the University of California at Davis School of Medicine, conducted a case-control study including 1032 PBC patients and 1041 controls. The patients were recruited from 23 medical centers throughout the United States. The controls were generated from random telephone dialing and were matched to cases by sex, age, race and geographical location. All participants completed an extensive telephone questionnaire covering demographics, lifestyle, personal and familial medical history, and reproductive and occupational history. Researchers then analyzed and compared the data.

After multivariable statistical analyses, they found a number of factors significantly associated with PBC. These include a family history of PBC or Sjogren's syndrome, individual history of urinary tract infection, history of smoking, use of nail polish, and history of hormone replacement thera
'"/>

Contact: David Greenberg
dgreenbe@wiley.com
201-748-6484
John Wiley & Sons, Inc.
1-Nov-2005


Page: 1 2

Related medicine news :

1. CAM-oriented primary care providers result in cost savings, high patient satisfaction
2. To what extent are emergency departments being used for primary care?
3. Study finds decline in nursing faculty primary barrier to nursing program expansion
4. ACP: Residency match results for internal medicine underscore need to redesign primary care
5. Medicare payment cuts will accelerate primary care collapse
6. Psychological therapies for common anxiety disorder not readily available in primary care settings
7. VIRTUE clinical trial opens to primary immunodeficiency patients across the U.S.
8. Coordination of primary health care and hospital care reduces readmission in COPD
9. New funding for research in primary health care
10. Calorie restriction appears better than exercise at slowing primary aging
11. New book looks at menstrual disorders in primary care

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:9/3/2020)... (PRWEB) , ... September 03, 2020 , ... ... it is sponsoring the American Foundation for Suicide Prevention’s (AFSP) annual signature event, ... million people across hundreds of U.S. cities to raise awareness of suicide prevention. ...
(Date:9/2/2020)... ... 02, 2020 , ... RAM Technologies, Inc., the perennial leader ... Special Needs plans, is proud to support the 2020 National Conferences on Medicare, ... supporting the event as a sponsor and exhibitor and will be showcasing their ...
(Date:9/1/2020)... ... 01, 2020 , ... Dr. Kiran Gill is a Board ... the face, breast, and body. In 2018, she founded Aesthetics in Plastic Surgery ... aesthetic practice in Southwest Florida. Dr. Gill and her team offer surgical and ...
(Date:8/31/2020)... , ... August 31, 2020 , ... Want to get ... Cerebral Palsy Alliance Research Foundation (CPARF) is thrilled to launch its fourth annual STEPtember ... A fully virtual challenge, STEPtember meets everyone wherever they are at this moment — ...
(Date:8/31/2020)... ... , ... A Cure for Covid-19 “PTS” with Mediation & Hypnosis , At this very ... of panic, experiencing deep anxiety, immense stress, and right now are needing serious relief from ... people on the planet are experiencing a great degree of emotional discomfort, be it fear ...
Breaking Medicine News(10 mins):
(Date:8/27/2020)... MYERS, Fla. (PRWEB) , ... August 27, 2020 , ... ... Board of Directors. Dr. Friedman is an adult and pediatric neuro-oncologist who serves on ... University and as an educator at Duke University Medical School. , Internationally recognized, Dr. ...
(Date:8/26/2020)... ... August 26, 2020 , ... ... Services, Laboratory Testing division, expands its technology footprint with the addition of ... platforms available. With industry-leading biomarker solutions, complemented with traditional ligand-binding assays and ...
(Date:8/26/2020)... ... August 26, 2020 , ... Crossroads Hospice ... added CHC and CPCO to her name. , That’s thanks to her completion ... and the Certified Professional Compliance Officer (CPCO.) , The CHC is designed to ...
Breaking Medicine Technology:
Cached News: