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Cedars-Sinai medical tipsheet for June 2005

MOLECULAR CHANGE OCCURRING DURING BRAIN TUMOR PROGRESSION ALSO EVIDENT IN BREAST CANCER
A molecular change that takes place in the newly formed blood vessels of progressing brain tumors have now been documented in the most common type of breast cancer, as well. The molecular shift occurs in major proteins called laminins, important constituents of blood vessels. As tumors become increasingly invasive, the laminins normally found in blood vessels become altered in the blood vessels of the tumors as part of a process that enables the tumors to grow and metastasize. Observing these changes in the tissue of individual patients may offer physicians a way to accurately diagnose breast carcinoma and predict further development. The molecular mechanism itself is seen as a future target for therapy aimed at cutting off the oxygen and nutrients tumors require.

AFTER LUNG VOLUME REDUCTION SURGERY, EMPHYSEMA PATIENT LOOKS FORWARD TO YARD WORK
Lung volume reduction surgery is undergoing a renaissance as a treatment for emphysema the nation's fourth leading cause of death in part because a major National Institutes of Health study published in 2003 identified which patients were viable candidates. Much of that research was conducted by Cedars-Sinai physicians and surgeons. Charlotte Kelley, diagnosed with emphysema more than 25 years ago, recently underwent LVRS. "There are just so many things that are a breeze now," she said. " I no longer spend every moment thinking about whether I can do this or do that, or if I'm going to be able to breathe or not."

STAR JONES REYNOLDS, PAULETTA AND DENZEL WASHINGTON AWARD SCHOLARSHIPS IN MAY 19 CEREMONY
Star Jones Reynolds, Pauletta and Denzel Washington, and neurosurgeon Keith Black awarded scholarships to two young neuroscientists during a May 19 ceremony in New York. Kimberly Idoko and Ksenia Prosolovich will conduct research in neuroscience under the direction of noted physicians a
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Contact: Glenda Collins
glenda.collins@cshs.org
310-423-2103
Cedars-Sinai Medical Center
20-Jun-2005


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4. Pauletta and Denzel Washington to present Cedars-Sinai neuroscience scholarships June 7
5. Cedars-Sinai researchers discover treatment for deadly brain tumors and infections
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8. Cedars-Sinai medical tipsheet for December 2005
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