HOME >> MEDICINE >> NEWS
Chemicals in curry and onions may help prevent colon cancer

A small but informative clinical trial by Johns Hopkins investigators shows that a pill combining chemicals found in turmeric, a spice used in curries, and onions reduces both the size and number of precancerous lesions in the human intestinal tract.

In the study, published in the August issue of Clinical Gastroenterology and Hepatology, five patients with an inherited form of precancerous polyps in the lower bowel known as familial adenomatous polyposis (FAP) were treated with regular doses of curcumin (the chemical found in turmeric) and quercetin, an antioxidant in onions, over an average of six months. The average number of polyps dropped 60.4 percent, and the average size dropped by 50.9 percent, according to a team led by Francis M. Giardiello, M.D., at the Division of Gastroenterology, The Johns Hopkins University School of Medicine, and Marcia Cruz-Correa, M.D., Ph.D., at Johns Hopkins and the University of Puerto Rico School of Medicine.

"We believe this is the first proof of principle that these substances have significant effects in patients with FAP," says Giardiello.

Familial adenomatous polyposis is a disorder that runs in families and is characterized by the development of hundreds of colorectal adenomas (polyps) and eventual colon cancer. Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been used to treat some patients with this condition, but these compounds often produce significant side effects, including gastrointestinal ulcerations and bleeding, according to Giardiello.

Previous observational studies in populations that consume large amounts of curry, as well as laboratory research on rodents have strongly suggested that curcumin -- a relatively innocuous yellow pigment extracted from turmeric, the powdered root of the herb curcuma longa and one of the main ingredients in Asian curries -- might be effective in preventing and/or treating cancer in the lower intestine, according to Cruz-Corre
'"/>

Contact: Eric Vohr
evohr1@jhmi.edu
410-955-8665
Johns Hopkins Medical Institutions
1-Aug-2006


Page: 1 2 3

Related medicine news :

1. Occupational and Environmental Exposures of Skin to Chemicals-2005
2. Chemical found in curry may help immune system clear amyloid plaques found in Alzheimers disease
3. Ingredient that makes curry yellow effective against melanoma cells
4. New tools used to control foodborne hepatitis A outbreaks related to green onions
5. Using MRI for diagnosis could help prevent breast cancer progression
6. Warfarin better than aspirin at stroke prevention in elderly people with atrial fibrillation
7. Bioengineering to prevent iron deficiency?
8. Should adult male circumcision be recommended for HIV prevention in the US?
9. Scaling up HIV prevention programs is cost effective
10. Early-morning Friday classes may prevent students from getting sloppy on thirsty Thursdays
11. Meningitis: effectiveness of preventive vaccination demonstrated

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/9/2018)... ... August 09, 2018 , ... Lyme disease is one of the fastest growing ... estimated 329,000 – a 25-fold increase since surveillance began in 1982. According to a ... all 50 states and the District of Columbia. Yet, Lyme and other insect borne ...
(Date:8/9/2018)... ... August 09, 2018 , ... ... with Smart-pill bottle and mobile applications, DoseSmart announced today the availability of ... DoseSmart medication management and medication adherence platform helps hospitals and health systems ...
(Date:8/9/2018)... ... August 09, 2018 , ... ... Coover and the company’s independent distributors, customers, and employees, the newly established ... fundraising, exceeding the $2 million goal. 100 percent of the donations will fund ...
(Date:8/7/2018)... ... ... Sussex Vision Center, a multi-site optometry practice with deep community roots in ... in Coldwater, and over the last three decades has added locations in Three Rivers ... services for patients of all ages. , “I wanted to find the right ...
(Date:8/7/2018)... CHURCH, Va. (PRWEB) , ... August 07, 2018 ... ... to announce the 30 talented nursing students selected to receive the 2018 ... encourage students to experience the rewarding field of psychiatric-mental health nursing and develop ...
Breaking Medicine News(10 mins):
(Date:8/3/2018)... ... August 03, 2018 , ... Flexefits, a pioneer in direct ... especially for its allowing participants in Direct Primary Care arrangements to keep HSA eligibility ... at $150 per individual and $300 per family per month.) , “We are very ...
(Date:8/2/2018)... , ... August 02, 2018 , ... UMD Professor Utpal ... $7.7 million over 5 years from the National Institute of Allergy and Infectious Diseases ... program to understand the immune responses of ticks that contribute to the spread of ...
(Date:8/2/2018)... (PRWEB) , ... August 02, ... ... single collaboration platform with customer relationship management (CRM), patient experience and provider ... the DirectTrust Accreditation Program for Health Information Service Providers (HISPs). DirectTrust ...
Breaking Medicine Technology:
Cached News: