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Chemotherapy may enhance the effectiveness of brain tumor vaccines

ding means that instead of having to receive the two therapies separately, patients might benefit from the delivery of a one-two punch to brain tumors, Sampson said.

Average survival for patients with newly diagnosed, surgically treated glioblastoma multiforme is 15 months with standard therapy, including chemotherapy. Patients who receive vaccine treatments with chemotherapy have exceeded expectations.

"Vaccines are an extremely promising new therapy for brain tumors, and the fact that their effectiveness may be augmented by chemotherapy represents the potential for an exciting new trend in brain tumor treatment," Sampson said.


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Contact: Lauren Shaftel
lauren.shaftel@duke.edu
919-452-2037
Duke University Medical Center
3-Jun-2007


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