HOME >> MEDICINE >> NEWS
Chemotherapy with bevacizumab increases risk of blood clots in arteries

Treatment with chemotherapy and bevacizumab, an anticancer drug, is associated with a greater risk of blood clots in patients arteries compared with treatment with chemotherapy only, according to a study published online August 7 in the Journal of the National Cancer Institute.

The combination of chemotherapy and bevacizumab has been shown to increase survival in patients with metastatic colorectal and nonsmall-cell lung cancer, but some previous studies suggest these patients are at an increased risk for blood clots in their arteries.

Frank Scappaticci, M.D., Ph.D., of Genentech, Inc. in South San Francisco, Calif., and colleagues analyzed data from five randomized controlled trials that included 1,745 patients with metastatic colorectal, breast, or nonsmall-cell lung cancer.

Among patients treated with the combination therapy, 3.8 percent experienced blood clots in their arteries, compared with 1.7 percent of patients on chemotherapy alone. There was no statistically significant difference in the incidence of blood clots in veins. Risk factors for blood clots in both arteries and veins included previous blood clots and older age (65 or older.)

The clinical benefit associated with bevacizumab therapy was maintained for all subgroups. Although death from [a blood clot in the artery] was uncommon, we did not capture functional disabilities from these events, and the risk factorsidentified in this study should be considered when making treatment decisions for individual patients, the authors write.


'"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
7-Aug-2007


Page: 1

Related medicine news :

1. Chemotherapy may enhance the effectiveness of brain tumor vaccines
2. Chemotherapy more effective when given before breast cancer surgery
3. Chemotherapy temporarily affects the structures of the human brain
4. Chemotherapy gel may fight breast cancer and reduce breast deformity
5. Chemotherapy given directly to the liver improves survival for patients with colorectal cancer
6. Chemotherapy after surgery extends survival for patients with advanced endometrial cancer
7. Chemotherapy errors rare, but have potential for serious consequences
8. Chemotherapy for brain tumors is boosted after vaccine targets resistance-related antigen
9. Chemotherapy options improve for patients with advanced colorectal cancer
10. Reduced greenhouse gas emissions required to avoid dangerous increases in heat stress
11. Risk of Parkinsons disease increases with pesticide exposure and head trauma

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/31/2020)... , ... August 31, 2020 , ... ... non-profit organization devoted exclusively to funding innovative lymphoma research and serving the lymphoma ... – today announced the 10th Anniversary of Blood Cancer Awareness Month (BCAM) and ...
(Date:8/31/2020)... ... August 31, 2020 , ... Colorado State University Global (CSU ... affordable online education – is proud to announce its new master’s degree in ... its kind in the nation, the 60-credit hour program is designed to provide ...
(Date:8/31/2020)... ... August 31, 2020 , ... ... both directly with persons with autism and other developmental disabilities, as well as ... intervention, parent education, adolescents with autism, school consultation, and staff development. She joined ...
(Date:8/28/2020)... ... August 28, 2020 , ... ... subscription to a customized Lighthouse Health & Wellness mobile app and web-portal. NCPCV ... project. Motorola Solutions Foundation awards grants each year to organizations, such as Destination ...
(Date:8/27/2020)... (PRWEB) , ... August 27, 2020 , ... ... has joined the Walk-in Dermatology team in its Greenvale, New York location. ... Nail and Skin Care Institute. She is certified in chemical peels, microdermabrasion, Hydrafacial ...
Breaking Medicine News(10 mins):
(Date:8/28/2020)... ... 2020 , ... Dr. Mark Surrey has been in practice for over ... clinical professor in the Department of OBGYN at UCLA’s David Geffen School of Medicine. ... Reproductive Society and is a Clinical Director of Fellowship Training for UCLA & Cedars ...
(Date:8/27/2020)... CONSHOHOCKEN, Pa. (PRWEB) , ... August 27, 2020 ... ... and care coordination software, today announced the successful completion of their 2020 System ... as well as their HITRUST® interim assessment and MARS-E compliance assessment. These achievements ...
(Date:8/27/2020)... ... 2020 , ... The flu season is right round the corner and the risk of getting ... necessary measures before it begins to harbor its effects on us. Already with the sudden ... huge impact on our lives. Hence it has become even more relevant to keep oneself ...
Breaking Medicine Technology:
Cached News: