HOME >> MEDICINE >> NEWS
Chemotherapy with bevacizumab increases risk of blood clots in arteries

Treatment with chemotherapy and bevacizumab, an anticancer drug, is associated with a greater risk of blood clots in patients arteries compared with treatment with chemotherapy only, according to a study published online August 7 in the Journal of the National Cancer Institute.

The combination of chemotherapy and bevacizumab has been shown to increase survival in patients with metastatic colorectal and nonsmall-cell lung cancer, but some previous studies suggest these patients are at an increased risk for blood clots in their arteries.

Frank Scappaticci, M.D., Ph.D., of Genentech, Inc. in South San Francisco, Calif., and colleagues analyzed data from five randomized controlled trials that included 1,745 patients with metastatic colorectal, breast, or nonsmall-cell lung cancer.

Among patients treated with the combination therapy, 3.8 percent experienced blood clots in their arteries, compared with 1.7 percent of patients on chemotherapy alone. There was no statistically significant difference in the incidence of blood clots in veins. Risk factors for blood clots in both arteries and veins included previous blood clots and older age (65 or older.)

The clinical benefit associated with bevacizumab therapy was maintained for all subgroups. Although death from [a blood clot in the artery] was uncommon, we did not capture functional disabilities from these events, and the risk factorsidentified in this study should be considered when making treatment decisions for individual patients, the authors write.


'"/>

Contact: Liz Savage
jncimedia@oxfordjournals.org
301-841-1287
Journal of the National Cancer Institute
7-Aug-2007


Page: 1

Related medicine news :

1. Chemotherapy may enhance the effectiveness of brain tumor vaccines
2. Chemotherapy more effective when given before breast cancer surgery
3. Chemotherapy temporarily affects the structures of the human brain
4. Chemotherapy gel may fight breast cancer and reduce breast deformity
5. Chemotherapy given directly to the liver improves survival for patients with colorectal cancer
6. Chemotherapy after surgery extends survival for patients with advanced endometrial cancer
7. Chemotherapy errors rare, but have potential for serious consequences
8. Chemotherapy for brain tumors is boosted after vaccine targets resistance-related antigen
9. Chemotherapy options improve for patients with advanced colorectal cancer
10. Reduced greenhouse gas emissions required to avoid dangerous increases in heat stress
11. Risk of Parkinsons disease increases with pesticide exposure and head trauma

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:11/11/2019)... ... November 11, 2019 , ... ... primary care and occupational medicine, is expanding its long-term partnership with 919 ... engage franchise candidates. With more than 200 locations across the country, American Family ...
(Date:11/11/2019)... (PRWEB) , ... November 11, 2019 , ... Dr. John ... Department of Health and Human Services’ (HHS) Pain Management Best Practices Task Force (Pain ... , This meeting was in follow up to the HHS Pain Task Force’s final ...
(Date:11/9/2019)... ... November 08, 2019 , ... The Women’s Dermatologic Society (WDS) announced ... concerns. The WDS Board of Directors appointed Molly Hinshaw, MD to fill the remainder ... March 2019-March 2020 term and will be presented to the membership as the 2020-2021 ...
(Date:11/9/2019)... ... November 08, 2019 , ... Mount Sinai Medical-Legal Partnership (MSMLP), ... two initiatives that provide free special education law and advocacy assistance to families and ... Sinai that also honored the work of contributions of Blaine (“Fin”) Fogg, who was ...
(Date:11/7/2019)... ... ... Atlantic Ultraviolet Corporation makes it their business to fight the flu. The first ... season starts in October until March, Atlantic Ultraviolet makes it a point to host ... get their shot. , Ann Wysocki, COO of Atlantic Ultraviolet Corporation® says, “Atlantic Ultraviolet ...
Breaking Medicine News(10 mins):
(Date:11/11/2019)... ... 10, 2019 , ... A gifted actor and generous philanthropist, Laurence Fishburne, will ... an episode of "Behind The Scenes." The growth of health management tools in health ... staff. This segment will focus on which tools are the most successful in allowing ...
(Date:11/9/2019)... ... November 08, 2019 , ... As part ... sets aside a day to help raise awareness and improve diagnosis of a ... Unlike some forms of PH, CTEPH has several treatment options, including a potentially ...
(Date:11/9/2019)... ... November 09, 2019 , ... “Strong, silent” types ... hallmark of much-loved, fictional British characters, like James Bond and Sherlock Holmes, and, ... admire about calm stoicism, even in the most perilous and dire of situations? ...
Breaking Medicine Technology:
Cached News: