HOME >> MEDICINE >> NEWS
Children's Hospital and Pitt lead national trial of hypothermia to treat pediatric brain injury

PITTSBURGH May 17, 2007 A renowned Children's Hospital of Pittsburgh of UPMC neurosurgeon will lead a $11.5 million National Institutes of Health-funded clinical trial examining the effectiveness of induced hypothermia as a therapy for brain swelling in children who have suffered traumatic brain injuries.

P. David Adelson, MD, director of the Pediatric Neurotrauma Center at Children's and the A. Leland Albright Professor of Neurosurgery at the University of Pittsburgh School of Medicine, will lead researchers at 12 sites throughout the country.

Researchers plan to enroll 340 children up to age 16 in the five-year, Phase III randomized trial, which is being funded by the National Institute of Neurological Disorders and Stroke. In Pittsburgh, Children's will serve as the clinical site for the study and Pitt will serve as the coordinating site.

A previous Phase II clinical trial of induced hypothermia therapy led by Dr. Adelson at Children's found that moderate hypothermia therapy is safe and may potentially improve outcome. Results of that study were published in the journal Neurosurgery in April 2005.

"We've proven this therapy is safe. Now if we can determine that it is effective, it would be a major breakthrough because currently there are very limited treatments that improve outcome following traumatic brain injury in children," Dr. Adelson said. "The belief is that cooling impacts the cascade of events that leads to brain swelling. Reducing brain swelling potentially could prevent further injury."

Patients in the study selected to receive hypothermia therapy will be cooled to between 3233 degrees Celsius (8990 degrees Fahrenheit), using special cooling blankets and/or cooled saline injected intravenously. They will be cooled for 48 hours and then followed by researchers for one year to track outcomes, with a battery of tests being conducted at six and 12 months following injury.


'"/>

Contact: Marc Lukasiak
marc.lukasiak@chp.edu
412-692-7919
Children's Hospital of Pittsburgh
17-May-2007


Page: 1

Related medicine news :

1. Support for Childrens Health and Medicare Protection Act given to House leaders by ACP
2. Childrens brain responses predict impact of sleep loss on attention
3. Childrens Hospital Boston presents at the American College of Cardiology Scientific Sessions
4. Childrens packed lunches: Are they even worse than Turkey Twizzlers?
5. Childrens Hospital Oakland Research Institute -- cancer study
6. Childrens Hospital Boston neurosurgeons to perform brain tumor removal during live Web cast
7. Study by Childrens Hospital and Carnegie Mellon explains crucial deficit in children with autism
8. Ear infection expert from Childrens Hospital of Pittsburgh leads interactive demo on diagnosis
9. Cincinnati Childrens researchers publish findings on potential target for leukemia treatment
10. Childrens Hospital of Pittsburgh and UPMC surgeons save two lives with domino transplant
11. Johns Hopkins Childrens Center to lead largest-ever study on kidney disease in children

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/28/2020)... ... May 28, 2020 , ... With a growing number of ... student housing are scrambling to implement practices that will help reduce residents’ risk ... beds on 38 campuses across the country, has researched best practices and identified ...
(Date:5/27/2020)... ... 2020 , ... The podiatrists and foot doctors of Advanced Foot & Ankle ... and Ann Arbor Michigan. Dr. Tomasz Biernacki states that “Podiatrists can help ... the hospital. We have been seeing patients in the hospital for the past 3 ...
(Date:5/27/2020)... ... May 27, 2020 , ... ... Pollack, University of Washington Professor of Bioengineering, Founder & Editor of scientific ... & Vapor ( https://www.amazon.com/Fourth-Phase-Water-Beyond-Liquid-ebook/dp/B00N2ASKF2 ) , https://www.voiceamerica.com/episode/123059/the-fourth-phase-of-water , * ...
(Date:5/26/2020)... ... May 26, 2020 , ... Loyale ... patient messaging and IVR Advantage™--for Loyale customers. Talksoft pre-service messaging solutions complement ... texts, IVR reminders and email messages tailored to each stage of their ...
(Date:5/26/2020)... ... , ... Sex educator, activist, humanitarian, and Wicked Pictures star jessica drake ... 2020 AASECT Audio Visual Award for jessica drake's Guide to Wicked Sex: Senior Sex. ... feature non-actors in its demonstrations and narratives and was produced and distributed by Wicked ...
Breaking Medicine News(10 mins):
(Date:5/30/2020)... , ... May 30, 2020 , ... ... dealing with a host of new issues related to COVID-19. Recently, Wellness Expert ... to help expectant moms support their pregnancy and postpartum. , A video ...
(Date:5/28/2020)... NILES, Ill. (PRWEB) , ... May 28, 2020 ... ... reliable telehealth and remote patient-care products led M&S Technologies, leader and innovator in ... the introduction of M&S Technologies ’ web-based Vision Testing has been released ...
(Date:5/27/2020)... ... May 27, 2020 , ... ... Jeffrey Taub , a biomedical engineer with more than 25 years of experience ... joined the firm as an Expert Consultant. His expertise includes quality assurance, including ...
Breaking Medicine Technology:
Cached News: