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Children's surgeon to present results of new anti-rejection protocol at World Transplant Congress

eloped in Children's Pediatric Transplant Laboratory. The first determines the risk of rejection by replicating the transplant reaction between the child and his or her donor in a test tube. Results from 45 children suggest that future use of this type of testing may be to identify when anti-rejection drugs may be reduced safely, without causing organ rejection.

The second approach evaluates whether a child's predisposition to organ rejection, rejection-free state and tolerance is based on inherited abnormalities in the genetic code for "immune response" genes. Dr. Sindhi adds that although tolerance is a rare, it is an ideal outcome, whereby anti-rejection medications are no longer required.


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Contact: Melanie Finnigan
Melanie.Finnigan@chp.edu
412-692-5016
Children's Hospital of Pittsburgh
19-Jul-2006


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