HOME >> MEDICINE >> NEWS
Cholesterol treatment, including statins, may slow Alzheimer's disease progression

Cholesterol lowering drugs, including statins, may slow the progression of Alzheimer's disease, concludes a study in the Journal of Neurology Neurosurgery and Psychiatry.

The research team assessed the degree of brain function loss caused by Alzheimer's disease in 342 patients attending a memory clinic. They then monitored the progress of the disease for almost three years. The average age of the patients was 73. Most were women.

In all, 129 patients had abnormal cholesterol levels, almost half of whom were being treated exclusively with statins. Of the remainder, 105 had abnormal untreated cholesterol , and 108 had normal cholesterol levels. Drug treatment included fibrates or statins, or a mixture of both.

During the three years, all the patients deteriorated, but the disease progressed significantly more slowly in the patients given cholesterol lowering drugs. Progression of the disease was rated at 1.5 points a year in those given the drugs, 2.4 in those whose cholesterol was not treated, and 2.6 in those with normal cholesterol levels.

The risk factor profile for Alzheimer's disease, including high blood pressure and diabetes, scarcely differed between the two groups with abnormal cholesterol levels.

The authors conclude that cholesterol lowering drugs may effectively slow progression of Alzheimer's disease, but suggest that a large trial will be needed to confirm their findings.

An accompanying editorial argues that it is still too early to definitively conclude that cholesterol lowering treatment is a valid option for patients with Alzheimer's disease.

The editorial also points out that the research was not able to isolate the potential advantages of the drugs other than their ability to lower cholesterol.


'"/>

Contact: Teresa
thagan@bma.org.uk
44-207-383-6174
BMJ Specialty Journals
16-Nov-2005


Page: 1

Related medicine news :

1. Cholesterol-lowering drugs reduce risk of stroke, heart attack
2. Cholesterol in stroke patients exceeds national guidelines
3. Cholesterol-lowering drugs may be useful in an influenza pandemic
4. Cholesterol-lowering drugs not associated with increased breast cancer risk
5. Cholesterol levels discounted as a biological marker for suicide risk among alcoholics
6. Cholesterol levels and use of lipid-lowering drugs are not associated with breast cancer risk
7. Older patients with major depression live longer with appropriate treatment, Penn study shows
8. Boosting key protein in brain could improve seizure treatment, Stanford study finds
9. Cancer researchers confirm brain tumor genetic subtype informs treatment, predicts outcome
10. JRRD tipsheet: Focus on stroke, Parkinsons treatment, wheelchair durability
11. Asymptomatic HIV-infected newborns may benefit from early drug treatment, Stanford study shows

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/27/2016)... ... 2016 , ... A revolution is underway. Brooklyn-based company, ... for the millions of people who require these medical transport services annually. ... the use of technology. Now, SmartEMS has put forth an industry-changing app that ...
(Date:6/26/2016)... ... June 26, 2016 , ... Pixel Film Studios Released ProSlice Levels, a ... can give their videos a whole new perspective by using the title layers ... Film Studios. , ProSlice Levels contains over 30 Different presets to choose from. ...
(Date:6/25/2016)... ... June 25, 2016 , ... Experts from ... at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes Convention Center ... care topics including advance care planning, healthcare costs and patient and family engagement. ...
(Date:6/25/2016)... Lewisville, TX (PRWEB) , ... June 25, 2016 , ... ... in the United States, named Dr. Sesan Ogunleye, as the Medical Director of its ... be the facility Medical Director of our new Mesquite location,” said Dr. James M. ...
(Date:6/25/2016)... ... 2016 , ... Conventional wisdom preaches the benefits of moderation, whether it’s a ... the bar too high can result in disappointment, perhaps even self-loathing. However, those who ... , Research from PsychTests.com reveals that behind the tendency to set ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016  Global Blood Therapeutics, Inc. (GBT) ... developing novel therapeutics for the treatment of grievous ... the closing of its previously announced underwritten public ... the public offering price of $18.75 per share. ... offered by GBT. GBT estimates net proceeds from ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... and Markets has announced the addition of the ... their offering. ... products and provides an updated review, including its applications ... covering the total market, which includes three main industries: ...
(Date:6/24/2016)... , June 24, 2016 The Academy ... of recommendations that would allow biopharmaceutical companies ... with entities that make formulary and coverage decisions, a ... "value" of new medicines. The recommendations address ... not appear on the drug label, a prohibition that ...
Breaking Medicine Technology:
Cached News: