HOME >> MEDICINE >> NEWS
Cholesterol treatment, including statins, may slow Alzheimer's disease progression

Cholesterol lowering drugs, including statins, may slow the progression of Alzheimer's disease, concludes a study in the Journal of Neurology Neurosurgery and Psychiatry.

The research team assessed the degree of brain function loss caused by Alzheimer's disease in 342 patients attending a memory clinic. They then monitored the progress of the disease for almost three years. The average age of the patients was 73. Most were women.

In all, 129 patients had abnormal cholesterol levels, almost half of whom were being treated exclusively with statins. Of the remainder, 105 had abnormal untreated cholesterol , and 108 had normal cholesterol levels. Drug treatment included fibrates or statins, or a mixture of both.

During the three years, all the patients deteriorated, but the disease progressed significantly more slowly in the patients given cholesterol lowering drugs. Progression of the disease was rated at 1.5 points a year in those given the drugs, 2.4 in those whose cholesterol was not treated, and 2.6 in those with normal cholesterol levels.

The risk factor profile for Alzheimer's disease, including high blood pressure and diabetes, scarcely differed between the two groups with abnormal cholesterol levels.

The authors conclude that cholesterol lowering drugs may effectively slow progression of Alzheimer's disease, but suggest that a large trial will be needed to confirm their findings.

An accompanying editorial argues that it is still too early to definitively conclude that cholesterol lowering treatment is a valid option for patients with Alzheimer's disease.

The editorial also points out that the research was not able to isolate the potential advantages of the drugs other than their ability to lower cholesterol.


'"/>

Contact: Teresa
thagan@bma.org.uk
44-207-383-6174
BMJ Specialty Journals
16-Nov-2005


Page: 1

Related medicine news :

1. Cholesterol-lowering drugs reduce risk of stroke, heart attack
2. Cholesterol in stroke patients exceeds national guidelines
3. Cholesterol-lowering drugs may be useful in an influenza pandemic
4. Cholesterol-lowering drugs not associated with increased breast cancer risk
5. Cholesterol levels discounted as a biological marker for suicide risk among alcoholics
6. Cholesterol levels and use of lipid-lowering drugs are not associated with breast cancer risk
7. Older patients with major depression live longer with appropriate treatment, Penn study shows
8. Boosting key protein in brain could improve seizure treatment, Stanford study finds
9. Cancer researchers confirm brain tumor genetic subtype informs treatment, predicts outcome
10. JRRD tipsheet: Focus on stroke, Parkinsons treatment, wheelchair durability
11. Asymptomatic HIV-infected newborns may benefit from early drug treatment, Stanford study shows

Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/18/2019)... ... April 18, 2019 , ... The Coro Medical official ... Sardis Volunteer Fire Department. , As a small, volunteer-only department in rural Mississippi, ... the community and now, is the only department with life-saving equipment of this caliber ...
(Date:4/18/2019)... , ... April 18, 2019 , ... ... its first ever Cannabis Industry Report . The study—which considers consumers’ perceptions ... intersections with retail and manufacturing, offering insight into what kinds of products consumers ...
(Date:4/17/2019)... ... 17, 2019 , ... Historically, patients have been reluctant to ... changing. Whether because of demographic or generational changes, patients seem to have become ... In the past, efforts to publish performance data about doctors and hospitals were ...
(Date:4/17/2019)... ... April 17, 2019 , ... Ramneek Kumar Talwar and Vineet ... Gwangju, Korea, and has highly evaluated and confirmed iRINGER’s technology, a product that’s ... discussion of a potential partnership since then. , After sharing relevant ...
(Date:4/17/2019)... ... April 17, 2019 , ... Purple Biosciences ... This California-made supplement was designed to lessen the negative effects of alcohol, ... purchase via GotPurpleTree.com and Amazon.com . , According to the ...
Breaking Medicine News(10 mins):
(Date:4/18/2019)... ... 2019 , ... KVC Kentucky will host the 2nd Annual ... horse farm on May 17, 2019 to raise funds to support KVC Kentucky’s ... elegant venue highlights Kentucky's stunning farmland, prized Thoroughbred horses and beautiful equine architecture. ...
(Date:4/17/2019)... , ... April 17, 2019 , ... Salt Lake ... Honorary Doctorate recipients. They will receive their degrees at SLCC’s May 3 Commencement at ... the executive vice president over Corporate Affairs and Miller Family Philanthropy. Richards is president ...
(Date:4/17/2019)... (PRWEB) , ... April 17, 2019 , ... What do ... comedy livestream show? Hosted within the Texas Medical Center’s TMC Innovation Institute, the Healthcare ... 26th, 2019, followed by a review by potential employers — all featured in a ...
Breaking Medicine Technology:
Cached News: