HOME >> MEDICINE >> NEWS
Chronic middle ear infections linked to resistant biofilm bacteria

Direct evidence of bacterial biofilms has been found on the middle ear tissue of children who suffer from chronic ear infections, according to a study published today in the Journal of the American Medical Association (JAMA) by researchers from the Allegheny Singer Research Institute (ASRI) at Allegheny General Hospital in Pittsburgh, the Medical College of Wisconsin and Children's Hospital of Wisconsin in Milwaukee.

Biofilms are antibiotic resistant colonizations of bacteria that attach to surfaces and form a slime-like barrier that acts as a formidable defense mechanism, protecting the bacteria from eradication.

The discovery of biofilms in the setting of chronic otitis media represents a landmark evolution in the medical community's understanding about a disease that afflicts millions of children world-wide each year and further endorses the emerging biofilm paradigm of chronic infectious disease, said Garth Ehrlich, Ph.D., principal investigator and executive director of the ASRI Center for Genomic Sciences.

Over the past ten years, Dr. Ehrlich and J. Christopher Post, M.D., Ph.D., FACS, an Allegheny General Hospital pediatric ear specialist and medical director of the Center for Genomic Sciences, have pioneered the biofilm theory to explain the persistence of chronic ear infections. In 2002, the team published in JAMA (Apr 2002; 287: 1710 1715) the first animal evidence of biofilms in the middle ear, setting the stage for the current clinical investigation.

According to co-investigator Joseph E. Kerschner M.D., "Today's study completely alters the concept about how physicians should approach the treatment of children with otitis media. This historic finding sheds new light on the decreasing efficacy of antibiotics in treating kids with ear infections and has serious implications about the future direction of therapeutic research." Dr. Kerschner is associate professor of otolaryngology at the Medical College and ch
'"/>

Contact: Toranj Marphetia
toranj@mcw.edu
414-456-4700
Medical College of Wisconsin
11-Jul-2006


Page: 1 2 3 4

Related medicine news :

1. Chronic gum disease associated with tongue cancer
2. Chronic pain can drive you to distraction
3. Chronic fatigue syndrome impairs a persons slow wave activity during sleep
4. Chronic family turmoil and other problems cause physical changes
5. Chronic disease management quality improvement efforts yield better care delivery
6. Chronic pain up almost 40 percent among US workers in past decade
7. Chronic diseases and injuries now number one killer in rural India
8. Chronic diseases and injuries in Latin America and the Caribbean: Time for action
9. Chronic alcohol exposure can affect brain protein expression
10. Chronically high blood sugar linked to risk of cognitive impairment
11. Mount Sinai School of Medicine receives prestigious AAMC Grant for Chronic Illness Care education

Post Your Comments:
(Date:5/19/2013)... Seattle, Wa (PRWEB) May 19, 2013 Agora ... training program that covers guides on how to increase ... an innovative memory training method that helps people re-new their ... fight stress and beat depression caused by a fatigued mind. ... their mind razor sharp for a lifetime. The author claimed ...
(Date:5/19/2013)... 2013 Beginning Wednesday, May 29 and running ... (RRVBC) will feature “Hot Dog Wednesdays" and Ice Cold Slushies ... provide hot dogs and all the fixin's to donors on ... throughout the summer. “Donors are our lifeline. The summer months ... adequate blood supply. This is a small way for ...
(Date:5/19/2013)... Florida (PRWEB) May 19, 2013 ... market access, is pleased to unveil a new and ... environment that provides a powerful array of real-time communication ... in the US and abroad. , HE-Xpo is powered ... offer attendees the look and feel of being at ...
(Date:5/19/2013)... The Da Vinci robot lawyers at Wright ... nation’s first trial involving a Da Vinci surgical robot ... Court, was filed by the widow of a man ... a robot-assisted prostate removal, according to a report from ... lawsuit alleges those complication’s hastened his death. (Estate ...
(Date:5/18/2013)... Daily Gossip issued a press release last week to announce ... Colston, Daily Gossip’s spokesperson, told the press that the magazine ... Fat Loss Plan . , Shaun Hadsall was the ... time when nutritionists and fat loss gurus constantly told people ... diet is based on the Macro-Patterning scheme, according ...
Breaking Medicine News(10 mins):Health News:How To Increase Memory Power | How “Agora Health Limited” Helps People Improve Their Memory Naturally And Effectively – Health Review 2Health News:Hot Dog Wednesdays and Ice Cold Slushies Return to Rock River Valley Blood Center for the Summer 2Health News:HealthEconomics.Com Announces HE-Xpo, a New Virtual Trade Show Devoted to Healthcare Value and Market Access 2Health News:HealthEconomics.Com Announces HE-Xpo, a New Virtual Trade Show Devoted to Healthcare Value and Market Access 3Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 2Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 3Health News:Da Vinci Surgical Robot Lawyers at Wright & Schulte LLC Note Recent Developments in Da Vinci Robot Lawsuit Trial 4
(Date:5/17/2013)... SAN DIEGO , May 17, 2013 /PRNewswire/ ... today that its Fast-Track Advanced Technology Small Business ... National Institute of Allergy and Infectious Diseases (NIAID), ... (NIH), supporting the development of novel human antibody ... S. aureus or Staph) infections, including methicillin-resistant ...
(Date:5/17/2013)... 2013  Technology advances have had a profound ... a constantly evolving communication environment, companies need to ... with internal executives. It is challenging, however, to ... and tools that are part of today,s communication ... Best Practices, LLC explores the various internal communication ...
(Date:5/17/2013)... May 17, 2013  Sony Biotechnology Inc. ("Sony") today announced ... holder and 130um sorting chip.  Sony will also be exhibiting ... new SH800 Cell Sorter, the EC800 flow cytometer, and new ... CYTO 2013, which will be held at the ... Diego, California , from May 20 - 22.  ...
Breaking Medicine Technology:Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 2Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 3Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 4Internal Communication Strategies and Tactics that Resonate with Key Stakeholders and Drive Organizational Effectiveness 2Sony Delivers New Technology for Science to CYTO 2013 2
Cached News: