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Cinnamon, cloves improve insulin function, lower risk factors for diabetes, cardiovascular disease

who did not. At the end of the 30 days, individuals with diabetes who had been taking some level of clove supplementation showed a decrease in serum glucose from an average 225 to 150 mg/dL, triglycerides from an average 235 to 203 mg/dL, a decrease in serum total cholesterol from 273 to 239 mg/dL, and a decrease in LDL from 175 to 145 mg/dL. The individuals with diabetes who had not been taking clove capsules showed no differences. Serum HDL was not affected by consumption of cloves.

The people with diabetes who had been in the experimental group then were taken off clove supplementation and, after 10 days, their glucose, triglycerides, total cholesterol and LDL measured. Although these had begun to rise somewhat, all remained significantly lower than at the beginning of the study. Dr. Khan says the finding that intake of 1 to 3 grams of cloves per day lowered risk factors of diabetes without changing HDL concentration suggest strongly that cloves are beneficial for people with type 2 diabetes. Co-authors of the study in addition to Dr. Khan and Dr. Anderson are Dr. Syed Saceed Qadir, Agricultural University, Peshawar, Pakistan, and Dr. Khan Nawaz Khattak, HMC, Hayatabad, Peshawar, Pakistan. The research was supported by the Higher Education Commission of Pakistan.

The effect of cinnamon is a major research interest in Dr. Anderson's laboratory, where human studies are now taking place looking at how this ingredient can improve insulin functioning in women with polycystic ovary syndrome (a disease of insulin sensitivity in which perturbed hormone levels cause difficulty in getting pregnant, among other problems), people with type 2 diabetes and the prediabetic metabolic syndrome; and people who are very obese (because Dr. Anderson believes that improving insulin function will lead to improvements in weight and lean body mass).

A post doctoral fellow in the Anderson laboratory also is beginning to investigate whether impro
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Contact: Sarah Goodwin
ebpress@bellsouth.net
770-270-0989
Federation of American Societies for Experimental Biology
4-Apr-2006


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