Columbia researchers restore memory lost in mice with A...( cond time they're placed in the cage a...)

Columbia researchers restore memory lost in mice with Alzheimer's

cond time they're placed in the cage, as they recognize the place where they were initially exposed to the stimulus. But mice with Alzheimer's-like changes do not remember the place, and continue moving within the cage. When the Alzheimer's mice were treated with Uch-L1, they acted like normal mice, and remained still.

"While this discovery is very promising, its proven effectiveness is limited to animal models and it will take some time before it could lead to therapies in humans," said Dr. Shelanski. "We continue to work towards that crucial goal." The work was supported by the National Institutes of Neurological Disease and Stroke and the Alzheimer's Center Program of the National Institute of Aging.

Contact: Craig LeMoult
cel2113@columbia.edu
212-305-3900
Columbia University Medical Center
24-Aug-2006

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