Columbia scientists present research findings at AHA Scientifi...( stem cell marker. They administered th...),Health

stem cell marker. They administered these cells in a rat model of heart failure by direct injection into the heart muscle and observed improvements in cardiac function and preservation of cardiac structure. They then examined the mechanisms by which these stem cells produce their beneficial effects. In examination of the rat hearts, the researchers found low rates of stem cell survival, leading them to hypothesize and then demonstrate in the second study that when these cells are injected into the heart, they release chemicals which promote the survival of cardiac muscle and the growth of new blood vessels and thereby support cardiac function. They will also present data which profiles the chemicals that these cells secrete.

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Contact: Craig LeMoult
cel2113@columbia.edu
212-305-0820
Columbia University Medical Center
14-Nov-2006

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