HOME >> MEDICINE >> NEWS
Combined contrast enhanced MRI shows promise

Combined contrast enhanced (CCE) MRI, in which two contrast agents are used together, permits accurate non-invasive staging of liver fibrosis in non-alcoholic fatty liver disease (NAFLD), according to a new study by researchers from the University of California, San Diego.

For the study, the researchers reviewed 26 patients with NAFLD who underwent CCE MRI. Using a five-point scale, the researchers found that the staging of the NAFLD on CCE MRI closely matched the staging of NAFLD using conventional pathology.

According to the researchers, the prevalence of NAFLD is increasing in western nations and is a major health problem affecting both children and adults. It is a common cause of cirrhosis in American adults and the most common cause in children.

The definitive method of diagnosis and staging is liver biopsy, but it has several limitations, say the researchers. It is invasive, costly, has risks and only samples about 1/50,000th of the liver. "This sampling issue is important because the pathological processes that affect the NAFLD liver are not evenly distributed throughout, so that tiny changes in needle placement will result in potentially large changes in biopsy interpretation. Because of these limitations, alternative methods such as CCE MR need to be developed," said Claude Sirlin, MD, lead author of the study.

"Except for CCE MR, all other experimental techniques rely on surrogate or indirect markers of fibrosis. CCE MR attempts to directly visualize fibrosis by using two contrast agents with complementary mechanisms, iron particles to darken the background liver and gadolinium to brighten the fibrosis," said Dr. Sirlin, "Gadolinium alone and iron particles alone are not adequate for visualization of fibrosis, unless the fibrosis is extremely advanced. However, when given together, the agents show fibrosis with high clarity," he added.

The combined use of two or more complementary contrast agents is uncommon in r
'"/>

Contact: Necoya Lightsey
necoya@arrs.org
604-647-7413
American Roentgen Ray Society
1-May-2006


Page: 1 2

Related medicine news :

1. Combined molecular-targeted and hormonal therapies offer promise in treating ovarian cancer
2. Combined imaging approach may provide better identification of difficult-to-diagnose brain clots
3. Combined therapies may boost immune response and long-term protection against brain tumors
4. Combined liver-kidney transplant beneficial for patients with dual organ disease
5. Combined treatment cuts inflammatory cells in chronic obstructive pulmonary disease
6. Combined MRI and mammography more effective at detecting breast cancer in high-risk women
7. Fluorescence diffuse optical tomography provides high contrast, 3-D look at breast cancer
8. MRI contrast agent can detect heart attack in the making
9. High-resolution imaging with contrast agent shows promise in osteoarthritis research
10. Using contrast enhanced sonography improves diagnosis of liver and spleen injuries
11. Reducing contrast material injection in elderly patients can lower cost of exam and risks

Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Combined contrast enhanced MRI shows promise

(Date:3/4/2015)... New York, New York (PRWEB) March 04, 2015 ... ( http://www.lipitorlawsuitcenter.com/ ) that allege the statin drug caused ... forward in the U.S. District Court, District of South ... Conference will be convened on March 26, 2015 at ... have been directed to submit a Joint Status report ...
(Date:3/4/2015)... WV (PRWEB) March 04, 2015 TROY ... (TSPE) software, which provides the ultimate level of security ... at the Hilton Houston Plaza Medical Center located at ... , Beginning at 7 AM, TROY Healthcare Solutions ... TROY Healthcare Solutions will offer brief presentations each hour ...
(Date:3/4/2015)... FDA’s New Inspection Approach:, What Your Inspector ... 2015 — 1:30 p.m. – 3:00 p.m. EDT, ... hours of an inspection whether a manufacturer’s in trouble ... list, they’ll merely ask for reassurance that they know ... “bad” list, the manufacturer must get ready to convince ...
(Date:3/4/2015)... March 04, 2015 Cook For Your ... that teaches healthy cooking to people touched by cancer, ... Lodge. The program, run by founder Ann Ogden, will ... Sport Management. The unique partnership will expand the program ... founded CFYL in 2007. After going through her own ...
(Date:3/4/2015)... 2015 The ability of volumetric ... assessment and help improve breast cancer risk prediction ... for presentation at the European Congress of Radiology ... - eight posters and 2 session presentations - ... density and quantitative breast imaging software tools to ...
Breaking Medicine News(10 mins):Health News:Lipitor Lawsuit News: Bernstein Liebhard LLP Comments on Scheduling of Status Conference in Federal Lipitor Litigation 2Health News:Lipitor Lawsuit News: Bernstein Liebhard LLP Comments on Scheduling of Status Conference in Federal Lipitor Litigation 3Health News:TROY Healthcare to Offer Prescription Solutions that can save a Hospital $100,000 2Health News:TROY Healthcare to Offer Prescription Solutions that can save a Hospital $100,000 3Health News:FDAnews Announces: FDA’s New Inspection Approach: What Your Inspector Knows in Four Hours Webinar, March 24, 2015 2Health News:FDAnews Announces: FDA’s New Inspection Approach: What Your Inspector Knows in Four Hours Webinar, March 24, 2015 3Health News:FDAnews Announces: FDA’s New Inspection Approach: What Your Inspector Knows in Four Hours Webinar, March 24, 2015 4Health News:Drexel University and Cook for Your Life Team Up 2Health News:Drexel University and Cook for Your Life Team Up 3Health News:Drexel University and Cook for Your Life Team Up 4Health News:Drexel University and Cook for Your Life Team Up 5Health News:Research Finds Use of Volpara Solutions’ Quantitative Breast Imaging Tools Help Reduce Subjectivity in Density Assessment and Improve Breast Cancer Risk Prediction 2Health News:Research Finds Use of Volpara Solutions’ Quantitative Breast Imaging Tools Help Reduce Subjectivity in Density Assessment and Improve Breast Cancer Risk Prediction 3Health News:Research Finds Use of Volpara Solutions’ Quantitative Breast Imaging Tools Help Reduce Subjectivity in Density Assessment and Improve Breast Cancer Risk Prediction 4Health News:Research Finds Use of Volpara Solutions’ Quantitative Breast Imaging Tools Help Reduce Subjectivity in Density Assessment and Improve Breast Cancer Risk Prediction 5
(Date:3/4/2015)... 4, 2015 Following the reintroduction of ... Center (LAC) released a report today urging policymakers ... and heroin epidemic through more effective use of ... "The Case for Expanding Access to Medication-Assisted Treatment ... the health, justice, and economic advantages of medication-assisted ...
(Date:3/4/2015)...  Bayer HealthCare today announced that the U.S. ... company,s Biologics License Application (BLA) for BAY 81-8973, ... FDA approval of the investigational compound, proposed trade ... in children and adults. "Bayer ... hemophilia A patients who need them," said ...
(Date:3/4/2015)... --  HeartWare International, Inc . (NASDAQ: HTWR ... support technologies that are revolutionizing the treatment of advanced ... is scheduled to present at the 2015 Barclays ... Tuesday, March 10, 2015.  The conference is being held ... Florida . A live ...
Breaking Medicine Technology:Improved Medication-Assisted Treatment Policy Could Aid Epidemic of 20 Million Americans with Untreated Addiction 2FDA Accepts Bayer's Biologics License Application for Investigational Treatment Option in Hemophilia A 2FDA Accepts Bayer's Biologics License Application for Investigational Treatment Option in Hemophilia A 3HeartWare Presentation At The 2015 Barclays Global Healthcare Conference To Be Webcast 2
Cached News: